DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7579 and galnt1

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	XP_009290644.1	Gene:	galnt1 / 559073	ZFINID:	ZDB-GENE-030131-2360	Length:	557	Species:	Danio rerio

Alignment Length:	509	Identity:	168/509 - (33%)
Similarity:	251/509 - (49%)	Gaps:	53/509 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LVDAQLQNEKY-------QYNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEH 63
            :|.|:.|.||.       |:|...||.|.|.|:|.|.|...|....|..:...| |:||....|.
Zfish    63 VVIAKDQQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDDLPRT-SVVIVFHNEA 126

  Fly    64 PHTLLRGIYSVITQTSPYLLKEIVLVHDGHPDLDLIRHIHH---KLPIVIQ-LEMESSKGIIHAR 124
            ..||||.::|||.::..:||:|||||.|......|.|.:.|   ||.:.:: :.||...|:|.||
Zfish   127 WTTLLRTVHSVIDRSPRHLLEEIVLVDDASERDFLKRQLEHYVRKLEVPVRVVRMEQRSGLIRAR 191

  Fly   125 LTGAGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVEPEQLA 189
            |.||.::||.::.||:.|.|.|.|||.|||..|.|:.:||..||:|.||.::|.|....:.....
Zfish   192 LKGASISTGQVITFLDAHCECTTGWLEPLLSRIKLDKKTVVCPIIDVISDDTFEYMAGSDMTYGG 256

  Fly   190 FDWQLDHIFLPLDQHSWN------SLPKPYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGGDAL 248
            |:|:|:..:.|:.|...:      :||...|:  :.|.:|:|||.:|..:|.:|.|:..:||:.|
Zfish   257 FNWKLNFRWYPVPQREMDRRKGDRTLPVRTPT--MAGGLFSIDRDYFQEIGTYDAGMDIWGGENL 319

  Fly   249 ELSLKVWQCGGLILAVPCSRVGIIYKRDELEAQMAPNRNP---SLQVQKNFKRVVDVWLDEYKLH 310
            |:|.::|||||.:..|.||.||.::::      ..|...|   ...:.||.:|:.:||:||:|..
Zfish   320 EISFRIWQCGGTLEIVTCSHVGHVFRK------ATPYTFPGGTGQIINKNNRRLAEVWMDEFKNF 378

  Fly   311 FYRYNPKLRNLTAESLDKPRDLRRRLNCKSFEWYRSQVAP--QIRNHFLHAGLTNYPIGKIMPFV 373
            ||..:|.:..:....:.....||:||.||.|.||...|.|  ||..|:       |.:|:|.. |
Zfish   379 FYIISPGVTKVDYGDISTRTSLRQRLQCKPFSWYLENVYPDSQIPRHY-------YSLGEIRN-V 435

  Fly   374 APHFCL-------SIKGGFPVIRKCHSTNFED-WTLTSRCQLKHGNMCLDVDYKNN-VRATKCTK 429
            ..:.||       :.|.|   |..||...... ::.|:..:::..::||||...|. |...||..
Zfish   436 ETNQCLDNMARKENEKVG---IFNCHGMGGNQVFSYTANKEIRTDDLCLDVSKLNGPVMMLKCHH 497

  Fly   430 KLSKNPWHYNYQHSSFVS-NGNKCLQIDVNKVGLILSACD-SDVTEQRWMFTKV 481
            ......|.|:....|.|. |.|:||.........:.|..| |....|:|:...|
Zfish   498 LKGNQLWEYDPVKLSLVHVNSNQCLDKASEDDSQVPSVRDCSGARSQQWLLRNV 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	105/296 (35%)
		pp-GalNAc-T	54..349	CDD:133004	111/307 (36%)
		RICIN	367..478	CDD:238092	32/121 (26%)
		Ricin_B_lectin	373..476	CDD:279046	29/113 (26%)
galnt1	XP_009290644.1	pp-GalNAc-T	117..417	CDD:133004	111/307 (36%)
		RICIN	430..548	CDD:238092	32/121 (26%)
		Ricin_B_lectin	430..546	CDD:279046	31/119 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810