Protein Alignment CG7579 and GALNT9

DIOPT Version :10

• Sequence 1: NP_648799.1
• Gene: CG7579 / 39714
• FlyBaseID: FBgn0036528
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_001116108.1
• Gene: GALNT9 / 50614
• HGNCID: 4131
• Length: 603
• Species: Homo sapiens
• Alignment Length: 520
• Identity: 144/520 - (27%)
• Similarity: 248/520 - (47%)
• Gaps: 85/520 - (16%)

  Fly     8 DAQLQNEKYQYNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPHTLLRGIY 72
            :|:.:.|:|.|||.||:||.|.|::.|||..:|.:::|:.: ...||:|.....|....:||.::
Human   109 EAEGKYEEYGYNAQLSDRISLDRSIPDYRPRKCRQMSYAQD-LPQVSVVFIFVNEALSVILRSVH 172

  Fly    73 SVITQTSPYLLKEIVLVHDGHPDLD----LIRHIHHKLPIVIQLEMESSK-GIIHARLTGAGVAT 132
            ||:..|...||||::||.|...:::    |.::::.:.|.::::...|.: |:|.|||.|...||
Human   173 SVVNHTPSQLLKEVILVDDNSDNVELKFNLDQYVNKRYPGLVKIVRNSRREGLIRARLQGWKAAT 237

  Fly   133 GDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVEPEQLA-----FDW 192
            ..::.|.:.|:|...||..|.|..|..:.:.:..|.:|.|...:|      |.:|.|     ::|
Human   238 APVVGFFDAHVEFNTGWAEPALSRIREDRRRIVLPAIDNIKYSTF------EVQQYANAAHGYNW 296

  Fly   193 QL--DHIFLPLDQHSWNSLPKPYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGGDALELSLKVW 255
            .|  .:|..|.|.........|..:..:.|..|.:||::|..:|..|.|:..|||:.:||.::||
Human   297 GLWCMYIIPPQDWLDRGDESAPIRTPAMIGCSFVVDREYFGDIGLLDPGMEVYGGENVELGMRVW 361

  Fly   256 QCGGLILAVPCSRVGIIYKRDELEAQMAP-NRNPSLQVQKNFKRVVDVWLDEYKLHFY-RYNPKL 318
            ||||.:..:|||||.      .:|....| |.:.....::|..|..:||:|::|.|.| .:|..:
Human   362 QCGGSMEVLPCSRVA------HIERTRKPYNNDIDYYAKRNALRAAEVWMDDFKSHVYMAWNIPM 420

  Fly   319 RNLTAE--SLDKPRDLRRRLNCKSFEWYRSQVAPQIRNHFLHAGLTNYPIGKIMPFVAPHFCL-- 379
            .|...:  .:.:...||:||.|:||:||...|.|::|   ::.....|  |::....|..:||
Human   421 SNPGVDFGDVSERLALRQRLKCRSFKWYLENVYPEMR---VYNNTLTY--GEVRNSKASAYCLDQ 480

  Fly   380 -SIKGGFPVIRKCHSTNFE------DWTL------------TSRCQLKHG-------NMCLDVDY 418
             :..|...::..||..:.:      |..|            .|:|.:..|       ..|.||
Human   481 GAEDGDRAILYPCHGMSSQLVRYSADGLLQLGPLGSTAFLPDSKCLVDDGTGRMPTLKKCEDV-- 543

  Fly   419 KNNVRATKCTKKLSKNPWHYNYQHSSFVSNG-NKCLQIDVNK-----VGLILSACDSDVTEQRWM 477
                  .:.|::|    |.:. |....||.. .:||:::::|     :.|::..|..    |:||
Human   544 ------ARPTQRL----WDFT-QSGPIVSRATGRCLEVEMSKDANFGLRLVVQRCSG----QKWM 593

  Fly   478  477
            Human   594  593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	pp-GalNAc-T	54..349	CDD:133004	93/310 (30%)
		beta-trefoil_Ricin_Pgant8-like	364..479	CDD:467339	30/148 (20%)
GALNT9	NP_001116108.1	Catalytic subdomain A	150..261		34/110 (31%)
		pp-GalNAc-T	154..453	CDD:133004	93/310 (30%)
		Catalytic subdomain B	318..380		25/67 (37%)
		beta-trefoil_Ricin_GALNT9	456..600	CDD:467351	31/160 (19%)