DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7579 and galnt6

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_998361.1	Gene:	galnt6 / 406477	ZFINID:	ZDB-GENE-040426-2272	Length:	619	Species:	Danio rerio

Alignment Length:	556	Identity:	163/556 - (29%)
Similarity:	246/556 - (44%)	Gaps:	133/556 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTETDLVDAQLQNEKYQYNAWLSERIPLKRTL-EDYRDPQCLKINYSSEKTV-TVSIVIAIQQEH 63
            ||:.:..:.|....::.:|.:.|:||.|.||| :|.|.|:|:...:.....: |.|::|....|.
Zfish   120 MTKEEEKEKQEGMTRHCFNQFASDRISLHRTLGDDTRPPECVDRKFRRCPALPTTSVIIVFHNEA 184

  Fly    64 PHTLLRGIYSVITQTSPYLLKEIVLVHDGHPDLDLIRHIHHK-------LPIVIQLEMESSKGII 121
            ..||||.:|||:..:....||||::|.|.    ....|:|.|       |.||..:.....||:|
Zfish   185 WSTLLRTVYSVLHTSPAAFLKEIIMVDDA----STAEHLHGKLEEYVKALKIVKVVRQPERKGLI 245

  Fly   122 HARLTGAGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVEPE 186
            .|||.||..|.|:||.||:.|.|...|||.|||..|:.....|..|.:..|...:|.:.|.|...
Zfish   246 TARLLGASKAEGEILTFLDAHCECFHGWLEPLLARIVEEPTAVVSPEITTIDLNTFQFHKPVATA 310

  Fly   187 QL----AFDWQLDHIFLPLDQHSWNSLP---------KPYP--SSQLEGRVFAIDRKWFWHLGGW 236
            :.    .|||.|        ...|..:|         :.||  :....|.:|:|.:.:|..:|.:
Zfish   311 RAHNRGNFDWSL--------TFGWEGIPDYENAKRKDETYPVKTPTFAGGLFSISKAYFEKIGTY 367

  Fly   237 DEGLRDYGGDALELSLKVWQCGGLILAVPCSRVGIIYKRDELEAQMAPNRNP--SLQVQKNFKRV 299
            |:.:..:||:.:|:|.:||||||.:..:|||.||.:::      ..:|:..|  :..:.:|..|:
Zfish   368 DDKMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFR------TKSPHTFPKGTEVITRNQVRL 426

  Fly   300 VDVWLDEYKLHFYRYNPKLRNLTAESLDKPR---------DLRRRLNCKSFEWYRSQVAPQIRNH 355
            .:||:|:|||.|||     |:.:|..:.|.:         .||..|.||:|.||.|.|.|:
Zfish   427 AEVWMDDYKLIFYR-----RSQSAAKMAKEKGFGDISDRLKLREDLQCKNFSWYLSNVYPE---- 482

  Fly   356 FLHAGLTNYPIGKIMPFVAP-----------HFCLSI----KGGFPVIR-KCHSTN----FEDWT 400
                        ..:|.::|           ..||.:    .||.|||. .||:..    ||
Zfish   483 ------------AFVPDLSPVKFGALKNRGAQQCLDVGESNNGGKPVIMYTCHNMGGNQYFE--- 532

  Fly   401 LTSRCQLKHG---NMCLDVD-YKNNVRATKCTKK------------------LSKNPWHYNYQHS 443
            .||..:|:|.   .:||... |...|:...||.|                  |.|||
Zfish   533 YTSHKELRHNIGKQLCLQASPYPEPVKIELCTLKGKGSSLAPEQEWLITEEQLLKNP-------- 589

  Fly   444 SFVSNGNKCLQIDVNKVGLILSACDSDVTEQRWMFT 479
               |:| |||....:|:  ::|.|:.|...|:|.|:
Zfish   590 ---SSG-KCLHKKGDKI--LMSPCNPDDHHQQWAFS 619

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	99/316 (31%)
		pp-GalNAc-T	54..349	CDD:133004	105/327 (32%)
		RICIN	367..478	CDD:238092	39/152 (26%)
		Ricin_B_lectin	373..476	CDD:279046	37/144 (26%)
galnt6	NP_998361.1	pp-GalNAc-T	175..480	CDD:133004	105/327 (32%)
		Ricin_B_lectin	493..616	CDD:279046	36/139 (26%)
		RICIN	494..618	CDD:238092	37/140 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586978
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830