DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7579 and CG7304

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster

Alignment Length:	499	Identity:	167/499 - (33%)
Similarity:	265/499 - (53%)	Gaps:	34/499 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VDAQLQNEKYQ-YNAWLSERIPLKRTLEDYRDPQCLKINY--SSEKTVTVSIVIAIQQEHPHTLL 68
            :|...|..:|. ||:||:|||||:|:|.|.||.:|.|:.|  .|::....||::..:.|....||
  Fly    63 IDEYTQGWRYYLYNSWLAERIPLRRSLPDLRDHRCQKLEYDEDSDEMKPASIIMIFRNEQLVVLL 127

  Fly    69 RGIYSVITQTSPYLLKEIVLVHDGHPDLD-------LI-------RHIHHKLPIVIQLEMESSKG 119
            |.::|::.:|..||..|::||:| |.|.|       ||       |:||.|..|   |.:....|
  Fly   128 RTLHSLVERTPKYLYIELILVND-HSDTDFWNDKLSLIFFDNYVHRYIHPKARI---LHLPEQVG 188

  Fly   120 IIHARLTGAGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVE 184
            :|.||...|..|..:.|||::..:|.|.|||.|||:.|...:.|:..||:|.:..::.||::.:|
  Fly   189 LIKARNLAASEAKAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPILDNLDEQTLAYQRSIE 253

  Fly   185 PEQLAFDWQLDHIFLPLDQHSWNSLPKPYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGGDALE 249
            ...: :||.|....:||.:...:.||.||..:.:...||||...||..:..:|..||.:|...||
  Fly   254 RRGM-YDWSLTRREVPLSRARRSHLPWPYEVAAVRTSVFAIPAVWFQDISNFDNNLRGFGAAELE 317

  Fly   250 LSLKVWQCGGLILAVPCSRVGIIYKRDE-LEAQMAPNRNPSLQVQKNFKRVVDVWLDEYKLHFYR 313
            ||.|||..||.|:.|||||||.:..:|| ...:.........|..:|.||:::||..:.|...|:
  Fly   318 LSFKVWCTGGRIVQVPCSRVGHLQPKDEDYLKRYGDLHKMGEQKSRNLKRIIEVWTGDLKSAIYK 382

  Fly   314 YNPKLRNLTAESLDKPRDLRRRLNCKSFEWYRSQVAPQIRNHFLHAGLTNYPIGKIMPFVAPHFC 378
            |.|.|.|::...|::||.|.::..|:||:.:.:.:.|.: ||......|:|..|.:.....|..|
  Fly   383 YQPHLLNISEGDLNEPRKLYKQNECQSFKEFINDITPGL-NHVAALNRTDYASGHVKTLEFPKKC 446

  Fly   379 LSI--KGGFPVIRKCHSTN-FEDWTLTSRCQLK-HGNMCLDVDYKNNVRA--TKCTKKLSKNPWH 437
            |:|  |.....:.:|.:.| .::||||....|: .||:|.:|  :.|:|.  :.|.....:..||
  Fly   447 LTINAKSQNLFLERCSTNNTLQNWTLTYVKDLRVAGNICAEV--RPNLRLGYSFCHSLGGRQSWH 509

  Fly   438 YNYQHSSFVSNGNKCLQIDVNKVGLILSACDSDVTEQRWMFTKV 481
            |:...:..:|| .|||:. .:::.:.|:.||:...:|||:...:
  Fly   510 YDSVSNQLMSN-TKCLEF-TDELNIFLAICDAANGKQRWILDNI 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	104/298 (35%)
		pp-GalNAc-T	54..349	CDD:133004	107/309 (35%)
		RICIN	367..478	CDD:238092	34/116 (29%)
		Ricin_B_lectin	373..476	CDD:279046	31/108 (29%)
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	43/126 (34%)
		pp-GalNAc-T	113..417	CDD:133004	107/308 (35%)
		Ricin_B_lectin	433..546	CDD:279046	32/116 (28%)
		RICIN	435..548	CDD:238092	34/116 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468123
Domainoid	1	1.000	43	1.000	Domainoid score	I12312
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG29074
OrthoDB	1	1.010	-	-		D276134at2759
OrthoFinder	1	1.000	-	-		FOG0001284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.860