DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7579 and CG31776

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_722909.2	Gene:	CG31776 / 33568	FlyBaseID:	FBgn0051776	Length:	630	Species:	Drosophila melanogaster

Alignment Length:	503	Identity:	182/503 - (36%)
Similarity:	272/503 - (54%)	Gaps:	41/503 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LVDAQLQNEKYQ-YNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPHTLLR 69
            |.:|:|..:.:| :.|.||:||||.|:|.|.|...|.|..| .|....|:::||...||...|||
  Fly   122 LPNAKLNPDDFQDFYAELSDRIPLNRSLPDTRPISCRKRKY-LENLPNVTVIIAFHDEHLSVLLR 185

  Fly    70 GIYSVITQTSPYLLKEIVLVHDGH--PDL--DLIRHIHHKLPIVIQ-LEMESSKGIIHARLTGAG 129
            .|.|:|.::...|||:||||.|..  |:|  .|...:....|.:|. |.:...:|.|.||:....
  Fly   186 SITSIINRSPVELLKQIVLVDDDSNLPELGQQLEEIVAQNFPKIIHILRLPERRGSIKARMEAIR 250

  Fly   130 VATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVEPEQLAFDWQL 194
            |::..:||||:.|:||...|||||||||::|...||.||:|||||::|||.|.....:..|:|.|
  Fly   251 VSSCQVLVFLDSHIEVNTNWLPPLLEPIVINPHIVTRPILDAISRKTFAYAKQNTMTRSGFNWWL 315

  Fly   195 DHIFLPLDQHSWNSLPKPYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGGDALELSLKVWQCGG 259
            :...||:.....:....||.:..|.| ..||||.:|.:|||:||.|..:..:..|:|.|||.|||
  Fly   316 ESESLPIFPEDKSPDSTPYRTPVLSG-AMAIDRNYFLNLGGFDEQLDTWEAEKFEISFKVWMCGG 379

  Fly   260 LILAVPCSRVGIIYKRDELEAQMAPNRNPSLQVQKNFKRVVDVWLDEYKLHFYRYNPKLRNL-TA 323
            ::|.|||:|||.|.|| .:::..:|..:..|  .:|:|||.:||:|.||.:.|..||||..: .|
  Fly   380 MMLYVPCARVGHIGKR-PMKSISSPGYHNFL--ARNYKRVAEVWMDNYKKYVYDKNPKLYKMANA 441

  Fly   324 ESLDKPRDLRRRLNCKSFEWYRSQVAPQIRNHFLHAGLTNYPI---GKIMPFVAPHFC---LSIK 382
            ..|.:.:..|..|.||:|:||.::|||.....:|   ..:.|:   |.|.....|.||   |:.:
  Fly   442 GLLFQRKTKRNALECKTFDWYMTKVAPDFLKRYL---ALDSPLVFSGVIESVAFPGFCVDSLNCR 503

  Fly   383 GGFPVI-RKCHSTN-----FEDWTLTSRCQLKHGNM---CLDVD--YKNNVRATKCTKKLSKNPW 436
            ...||: .:|...|     .::|:||...:::..|.   ||:..  ...:|...:|.|......|
  Fly   504 HTKPVVLARCTGHNSMPGEHQNWSLTQDHEIQLTNSKDDCLEAQGLRSKSVWLFRCHKNGGNQYW 568

  Fly   437 HYNYQHSSFVSNGN---KCLQIDV---NKVGLILS--ACDSDVTEQRW 476
            :||::| .::..|.   .||:..:   :|||.:|:  .||.:..||:|
  Fly   569 YYNHRH-RWIQQGQIWVWCLEAQLASGHKVGKVLANKICDKNQLEQQW 615

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	117/289 (40%)
		pp-GalNAc-T	54..349	CDD:133004	122/300 (41%)
		RICIN	367..478	CDD:238092	35/132 (27%)
		Ricin_B_lectin	373..476	CDD:279046	32/124 (26%)
CG31776	NP_722909.2	GT2	167..495	CDD:224137	131/334 (39%)
		pp-GalNAc-T	170..467	CDD:133004	122/300 (41%)
		Ricin_B_lectin	483..615	CDD:279046	34/132 (26%)
		RICIN	485..616	CDD:238092	35/132 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468130
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276134at2759
OrthoFinder	1	1.000	-	-		FOG0001284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850