DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7579 and Pgant7

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_001285406.1	Gene:	Pgant7 / 32836	FlyBaseID:	FBgn0030930	Length:	591	Species:	Drosophila melanogaster

Alignment Length:	502	Identity:	154/502 - (30%)
Similarity:	251/502 - (50%)	Gaps:	54/502 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KYQYNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPHTLLRGIYSVITQTS 79
            :|..|...|:.|.:.|::.|.|..:|...:|..:...| |::|....|....|:|.::|||.::.
  Fly   107 EYGMNIACSDEISMHRSVRDTRLEECRHWDYPFDLPRT-SVIIVFHNEGFSVLMRTVHSVIDRSP 170

  Fly    80 PYLLKEIVLVHDGHPDLDLIR-----HIHHKLPIVIQLEMESSKGIIHARLTGAGVATGDILVFL 139
            .::|.||:|| |...|.:.:|     ::.....:|..:..:..:|:|..|..||..|||:::|||
  Fly   171 THMLHEIILV-DDFSDKENLRSQLDEYVLQFKGLVKVIRNKEREGLIRTRSRGAMEATGEVIVFL 234

  Fly   140 NGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVEPE---QLAFDWQLDHIFLPL 201
            :.|.||...||||||.||..:...:|.||:|.|..::|.||.:...:   :..|:|.:
  Fly   235 DAHCEVNTNWLPPLLAPIYRDRTVMTVPIIDGIDHKNFEYRPVYGTDNHFRGIFEWGM------- 292

  Fly   202 DQHSWNSLPK-----------PYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGGDALELSLKVW 255
             .:..|.:|:           ||.|....|.:|||:|::|..||.:|.||..:||:..|||.|:|
  Fly   293 -LYKENEVPRREQRRRAHNSEPYRSPTHAGGLFAINREYFLELGAYDPGLLVWGGENFELSFKIW 356

  Fly   256 QCGGLILAVPCSRVGIIYKR------DELEAQMAPNRNPSLQVQKNFKRVVDVWLDE-YKLHFYR 313
            ||||.|..|||||||.:|:.      .:|.::   .:.|.:.:  |:|||::.|.|: :|.:||.
  Fly   357 QCGGSIEWVPCSRVGHVYRGFMPYNFGKLASK---KKGPLITI--NYKRVIETWFDDTHKEYFYT 416

  Fly   314 YNPKLRNLTAESLDKPRDLRRRLNCKSFEWYRSQVAPQIRNHFLHAGL-TNYPIGKIMPFVAPHF 377
            ..|..|.|....:.:...|::|||||||:|:...:|..:.:.|  .|| .|...|::.. ||...
  Fly   417 REPLARYLDMGDISEQLALKKRLNCKSFQWFMDHIAYDVYDKF--PGLPANLHWGELRS-VASDG 478

  Fly   378 CLSIKGGFPV----IRKCH-STNFEDWTLTSRCQLKHGNMCLDVDYKNNVRATKCTKKLSKNPWH 437
            ||...|..|.    :..|| ..|.:...|.:..||..|..|::.| :..::...|.......||.
  Fly   479 CLDSMGHQPPAIMGLTYCHGGGNNQLVRLNAAGQLGVGERCVEAD-RQGIKLAVCRLGTVDGPWQ 542

  Fly   438 YNYQHSSFVSN--GNKCLQIDVNKVGLILSACDSDVTEQRWMFTKVQ 482
            || :|:..:.:  ..||:.:......|.|..||.:.:.|:|.|.:::
  Fly   543 YN-EHTKHLMHRVHKKCMALHPATQQLSLGHCDVNDSYQQWWFKEIR 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	101/309 (33%)
		pp-GalNAc-T	54..349	CDD:133004	108/320 (34%)
		RICIN	367..478	CDD:238092	30/117 (26%)
		Ricin_B_lectin	373..476	CDD:279046	28/109 (26%)
Pgant7	NP_001285406.1	Glyco_tranf_2_3	142..373	CDD:290369	85/240 (35%)
		pp-GalNAc-T	145..452	CDD:133004	108/320 (34%)
		Ricin_B_lectin	468..582	CDD:279046	29/116 (25%)
		RICIN	469..584	CDD:238092	30/117 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457030
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840