DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7579 and Pgant5

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_001036338.1	Gene:	Pgant5 / 326151	FlyBaseID:	FBgn0031681	Length:	630	Species:	Drosophila melanogaster

Alignment Length:	515	Identity:	168/515 - (32%)
Similarity:	244/515 - (47%)	Gaps:	77/515 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DLVDAQLQNEKY---QYNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPHT 66
            |:.|  |..||:   |:|...|:.|.|.|:|.|.|...|.:.:|:| |..|.||||....|...|
  Fly   141 DMKD--LMKEKFKENQFNLLASDMISLNRSLTDVRHEGCRRKHYAS-KLPTTSIVIVFHNEAWTT 202

  Fly    67 LLRGIYSVITQTSPYLLKEIVLVHDGHPDLDLIRHIHH---KLPI-VIQLEMESSKGIIHARLTG 127
            |||.::|||.::...|||||:||.|......|.:.:..   |||: ...|..|...|:|.|||.|
  Fly   203 LLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYVAKLPVKTFVLRTEKRSGLIRARLLG 267

  Fly   128 AGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVEPEQLAFDW 192
            |...:|:::.||:.|.|.|.|||.|||..|:.|.:||..||:|.||.|:|.|....:.....|:|
  Fly   268 AEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCPIIDVISDETFEYITASDSTWGGFNW 332

  Fly   193 QLDHIFLPLDQHSWNSLPK------------PYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGG 245
            :|:        ..|..:|.            |..:..:.|.:|:||:.:|:.:|.:|||:..:||
  Fly   333 KLN--------FRWYRVPSREMARRNNDRTAPLRTPTMAGGLFSIDKDYFYEIGSYDEGMDIWGG 389

  Fly   246 DALELSLKVWQCGGLILAVPCSRVGIIYKRDELEAQMAPNRNP---SLQVQKNFKRVVDVWLDEY 307
            :.||:|.:||.|||::...||||||.::::.      .|...|   :..|..|..|:|:||||::
  Fly   390 ENLEMSFRVWMCGGVLEIAPCSRVGHVFRKS------TPYTFPGGTTEIVNHNNARLVEVWLDDW 448

  Fly   308 KLHFYRYNPKLRNLTAESLDKPRDLRRRLNCKSFEWYRSQVAPQIRNHFLHAGLTNYPIGKIMPF 372
            |..:|.:.|..|..:|..:...:.||.||.||||.||...|.|:..     ..|..|.:|:|..
  Fly   449 KEFYYSFYPGARKASAGDVSDRKALRDRLKCKSFRWYLENVYPESL-----MPLDYYYLGEIRN- 507

  Fly   373 VAPHFCLSIKGGFPVIRK---------CHSTNFED-WTLTSRCQLKHGNMCLDVDYKNN-VRATK 426
            .....||...|     ||         ||...... :..|.|.|:...::|||....|. |...:
  Fly   508 AETETCLDTMG-----RKYNEKVGISYCHGLGGNQVFAYTKRQQIMSDDLCLDASSSNGPVNMVR 567

  Fly   427 CTKKLSKNPWHYN-----YQHSSFVSNGNKCLQ----IDVNKVGLILSACDSDVTEQRWM 477
            |........|.|:     .:|    :|..:|||    .|.|..  :|..| |....|:|:
  Fly   568 CHNMGGNQEWVYDAEEKWIRH----TNTGQCLQRATRDDANTP--LLRPC-SYGKGQQWL 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	106/302 (35%)
		pp-GalNAc-T	54..349	CDD:133004	113/313 (36%)
		RICIN	367..478	CDD:238092	32/131 (24%)
		Ricin_B_lectin	373..476	CDD:279046	29/122 (24%)
Pgant5	NP_001036338.1	pp-GalNAc-T	190..490	CDD:133004	113/313 (36%)
Pgant5	NP_001036338.1	Ricin_B_lectin	503..619	CDD:395527	31/128 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457046
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840