DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7579 and Galntl6

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	XP_017168336.2	Gene:	Galntl6 / 270049	MGIID:	1913581	Length:	695	Species:	Mus musculus

Alignment Length:	524	Identity:	161/524 - (30%)
Similarity:	253/524 - (48%)	Gaps:	72/524 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTETDLVDAQLQNEKYQYNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPH 65
            :||.|..|:..:..  .:|.::|..|.|:|:|.|.|...| |.....|:....||:|....|...
Mouse   187 LTEEDRDDSAYREN--GFNIFVSNNIALERSLPDIRHANC-KHKMYLERLPNTSIIIPFHNEGWT 248

  Fly    66 TLLRGIYSVITQTSPYLLKEIVLVHDGHPDLDLIRHIHHKLPIVIQ-------LEMESSKGIIHA 123
            :|||.|:|:|.:|...|:.||:|| |...|.:   |:..||...:.       :..:..:|:|..
Mouse   249 SLLRTIHSIINRTPESLIAEIILV-DDFSDRE---HLKDKLEDYMARFSKVRIVRTKKREGLIRT 309

  Fly   124 RLTGAGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYR-KLVEPEQ 187
            ||.||.||.|::|.||:.|.||...||||||..|.||::|:..|::|.|....|.|. :..:..:
Mouse   310 RLLGASVARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMR 374

  Fly   188 LAFDWQLDHIFLPLDQHSWNSLPK-PYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGGDALELS 251
            .||||::.:..:|:......:.|. |:.|..:.|.:||:||||||.|||:|.||..:||:..|:|
Mouse   375 GAFDWEMYYKRIPIPPELQRADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEIS 439

  Fly   252 LKVWQCGGLILAVPCSRVGIIYKRDELEAQMAPNRNPS-LQVQKNFKRVVDVWLDEYKLHFYRYN 315
            .|||.|||.:..|||||||.||::      ..|.:.|| ..:.:|.|||.:.|:||:..:.|:..
Mouse   440 FKVWMCGGEMFDVPCSRVGHIYRK------YVPYKVPSGTSLARNLKRVAETWMDEFAEYIYQRR 498

  Fly   316 PKLRNLTAESLDKPRDLRRRLNCKSFEWYRSQVAPQIRNHFLHAGLTNYPIGKIMP-------FV 373
            |:.|:|:...:...::||:||.||.|:|:.:.||..:..:        ||..:.:|       .|
Mouse   499 PEYRHLSTGDISAQKELRKRLKCKDFKWFMAAVAWDVPKY--------YPPVEPLPAAWGEIRSV 555

  Fly   374 APHFCLSIKGGFPVIRKCHSTNFE-------------DW------TLTSRCQLKHG------NMC 413
            |.:.|:..|.|        :|..|             .|      |...|..::.|      ..|
Mouse   556 AANLCVDSKHG--------ATGTELRLDVCVKDGSERTWSHEQLFTFGWREDIRPGEPLHTRKFC 612

  Fly   414 LD-VDYKNNVRATKCTKKLSKNPWHYNYQHSSFVSNGNKCLQIDVNKVGLILSACDSDVTEQRWM 477
            || :.:.:.|....|........|.|....:.|....|.|:..:.::..:.::.||.....|:|:
Mouse   613 LDAISHSSPVTLYDCHGMKGNQLWGYREDRTLFHPVSNSCMDCNPSEKKIFMARCDPLSETQQWI 677

  Fly   478 FTKV 481
            |..:
Mouse   678 FEHI 681

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	109/293 (37%)
		pp-GalNAc-T	54..349	CDD:133004	115/304 (38%)
		RICIN	367..478	CDD:238092	26/143 (18%)
		Ricin_B_lectin	373..476	CDD:279046	24/128 (19%)
Galntl6	XP_017168336.2	pp-GalNAc-T	237..532	CDD:133004	115/304 (38%)
Galntl6	XP_017168336.2	Ricin_B_lectin	548..676	CDD:366226	24/135 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842562
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.940