DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7579 and Pgant4

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_001137779.1	Gene:	Pgant4 / 261610	FlyBaseID:	FBgn0051956	Length:	644	Species:	Drosophila melanogaster

Alignment Length:	529	Identity:	185/529 - (34%)
Similarity:	271/529 - (51%)	Gaps:	65/529 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DAQLQNEKYQ---YNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPHTLLR 69
            :.||:.|.|:   :|..:|:||.:.|::.|.|...|....|.: |...:|::.....||.:||||
  Fly   133 EKQLEKEHYEMNGFNGLISDRISVNRSVPDLRLEACKTRKYLA-KLPNISVIFIFFNEHFNTLLR 196

  Fly    70 GIYSVITQTSPYLLKEIVLVHDGHPDLDLIR---------HIHHKLPIVIQLEMESSKGIIHARL 125
            .|||||.:|.|.|||:||||.|| .:.|:::         |..|.:.||...|.:   |:|.||:
  Fly   197 SIYSVINRTPPELLKQIVLVDDG-SEWDVLKQPLDDYVQQHFPHLVTIVRNPERQ---GLIGARI 257

  Fly   126 TGAGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAY---RKLVEPEQ 187
            .||.||.|.::||.:.|:||...|||||:|||.:|.:..|.|:||.||.|.|:|   .|  :..:
  Fly   258 AGAKVAVGQVMVFFDSHIEVNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSYFSGNK--DGAR 320

  Fly   188 LAFDWQLDHIFLPLDQHSWNSLPK-------PYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGG 245
            ..|||::.:..||:       ||:       ||.|..:.|.:|||:..:||.|||:|:.|..:||
  Fly   321 GGFDWKMLYKQLPV-------LPEDALDKSMPYRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGG 378

  Fly   246 DALELSLKVWQCGGLILAVPCSRVGIIYKRDELEAQMAPNRNPSLQ--VQKNFKRVVDVWLDEYK 308
            :..|||.|:|.|||::|.||||||..|::     ..|.|..||...  |.||.|||.:||:||||
  Fly   379 EQYELSFKIWMCGGMLLDVPCSRVAHIFR-----GPMKPRGNPRGHNFVAKNHKRVAEVWMDEYK 438

  Fly   309 LHFYRYNPK-LRNLTAESLDKPRDLRRRLNCKSFEWYRSQVAPQIRNHFLHAGLTNYPIGKIMPF 372
            .:.|:.:|| ..||.|..|.:.|.:|.||.||||.|:.::|||.....|......:|..|.|...
  Fly   439 QYVYKRDPKTYDNLDAGDLTRQRGVRERLKCKSFHWFMTEVAPDFLVKFPPVEPPSYAAGIIQNV 503

  Fly   373 VAPHFCLSIKGGFP---------VIRKCHSTNFEDWTLTSRCQLK---HGNMCLDVDYKNNVRAT 425
            ..|.:||...|...         ...:.|....:.|.|:....|:   ..::|||| ::....||
  Fly   504 ANPVYCLDNMGKSTEEAVGMFSCADNRTHPQPNQFWELSIFRDLRMKGFDSVCLDV-HEGPPNAT 567

  Fly   426 ----KCTKKLSKNPWHYNYQHSSFV--SNGNKCLQ--IDVNKVGLILSACDSDVTEQRWMFTKVQ 482
                .|..:.....|:|:.|....|  .|..:||:  ::.....::.::|::....|||.|..|.
  Fly   568 VWMWSCHSQGGNQFWYYDRQTQRLVHGENNKRCLEGFVENGIAKVVANSCENGNDRQRWEFGFVN 632

  Fly   483 DFKLDHMRD 491
            ...||...|
  Fly   633 HTMLDTFYD 641

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	126/305 (41%)
		pp-GalNAc-T	54..349	CDD:133004	133/316 (42%)
		RICIN	367..478	CDD:238092	28/130 (22%)
		Ricin_B_lectin	373..476	CDD:279046	24/122 (20%)
Pgant4	NP_001137779.1	BcsA	169..>403	CDD:224136	101/247 (41%)
		pp-GalNAc-T	181..480	CDD:133004	133/316 (42%)
		Ricin_B_lectin	496..626	CDD:279046	26/130 (20%)
		RICIN	498..628	CDD:238092	28/130 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468129
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276134at2759
OrthoFinder	1	1.000	-	-		FOG0001284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850