DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7579 and Galnt9

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_938048.2	Gene:	Galnt9 / 231605	MGIID:	2677965	Length:	604	Species:	Mus musculus

Alignment Length:	518	Identity:	146/518 - (28%)
Similarity:	249/518 - (48%)	Gaps:	71/518 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ETDLVDAQLQNEKYQYNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPHTL 67
            :.|..:.:.:.|.:.|||.||:||.|.||:.|||..:|.:|.| ||....:|:|.....|....:
Mouse   105 QDDSQETEGKFEDFGYNAQLSDRISLDRTIPDYRPKRCRQITY-SEDLPQISVVFIFVNEALSVI 168

  Fly    68 LRGIYSVITQTSPYLLKEIVLVHDGHPDLD----LIRHIHHKLPIVIQLEMESSK-GIIHARLTG 127
            ||.::||:..|...||||::||.|...:::    |.:::|.:.|.::::...|.: |:|.|||.|
Mouse   169 LRSVHSVVNHTPSQLLKEVILVDDNSDNVELKFNLDQYVHKRYPGLVKVVRNSRREGLIRARLQG 233

  Fly   128 AGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVEPEQLA--- 189
            ..|||..|:.|.:.|:|...||..|.|..|..:.:.:..|.:|.|...:|      |.:|.|
Mouse   234 WKVATAPIVGFFDAHVEFNTGWAEPALARIQEDRRRIILPAIDNIKYSTF------EVQQYASAA 292

  Fly   190 --FDWQL--DHIFLPLDQHSWNSLPKPYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGGDALEL 250
              ::|.|  .:|..|.|.........|..:..:.|..|.:||::|..:|..|.|:..||.:.:||
Mouse   293 HGYNWGLWCMYIIPPQDWLDRGDESAPIRTPAMIGCSFVVDREYFGDIGLLDPGMEVYGAENIEL 357

  Fly   251 SLKVWQCGGLILAVPCSRVGIIYKRDELEAQMAP-NRNPSLQVQKNFKRVVDVWLDEYKLHFY-R 313
            .::||||||.:..:|||||.      .:|....| |.:.....::|..|..:||:|::|.|.| .
Mouse   358 GMRVWQCGGSMEVLPCSRVA------HIERTKKPYNNDIDYYAKRNALRAAEVWMDDFKSHVYMA 416

  Fly   314 YNPKLRNLTAE--SLDKPRDLRRRLNCKSFEWYRSQVAPQIRNHFLHAGLTNYPIGKIMPFVAPH 376
            :|..:.|...:  .:.:...||.:|.|:||:||...|.|::|   ::.....|  |::....|..
Mouse   417 WNIPMTNPGVDFGDVSERLALREKLKCRSFKWYLENVYPEMR---IYNNTLTY--GEVRNSKASG 476

  Fly   377 FCLSIKGG----FPVIRKCHSTNFEDWTLTSRCQLKHG----------NMCLDVDYKNNV-RATK 426
            :||. :|.    ..::..||..:.:....::...|:.|          :.||..|.:..: ...|
Mouse   477 YCLD-QGAEDDDRAILYPCHGMSSQLVRYSAEGLLQLGPLGSTAFLPDSKCLVDDGRGRMPTLKK 540

  Fly   427 C------TKKLSKNPWHYNYQHSSFVS-NGNKCLQIDVNK-----VGLILSACDSDVTEQRWM 477
            |      |::|    |.:. |....|| :..:||:::::|     :.|::..|..    |:||
Mouse   541 CEDVARPTQRL----WDFT-QSGPIVSRDTGRCLEVEMSKDANFGLRLVVQRCSG----QKWM 594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	88/299 (29%)
		pp-GalNAc-T	54..349	CDD:133004	94/310 (30%)
		RICIN	367..478	CDD:238092	28/138 (20%)
		Ricin_B_lectin	373..476	CDD:279046	25/129 (19%)
Galnt9	NP_938048.2	pp-GalNAc-T	155..454	CDD:133004	94/310 (30%)
		Ricin_B_lectin	465..593	CDD:279046	27/139 (19%)
		RICIN	467..595	CDD:238092	28/138 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842536
Domainoid	1	1.000	43	1.000	Domainoid score	I12312
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.830