DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7579 and gly-7

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_503512.1	Gene:	gly-7 / 178661	WormBaseID:	WBGene00001632	Length:	601	Species:	Caenorhabditis elegans

Alignment Length:	512	Identity:	153/512 - (29%)
Similarity:	242/512 - (47%)	Gaps:	62/512 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ETDLVDAQLQNEKYQYNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPHTL 67
            |..:...:...:::.:|.::|:.|.:.||:.|.|..:|...:| .||..|||:|:....|....|
Worm   109 EEGMAAGRAAEKEFGFNTYVSDMISMNRTIPDIRPEECKHWDY-PEKLPTVSVVVVFHNEGWTPL 172

  Fly    68 LRGIYSVITQTSPYLLKEIVLVHDGHPDLDLIRHIHHKLP--------IVIQLEMESSKGIIHAR 124
            ||.::||:.::.|.|::::|:|.|   |.|. .|:..||.        .||.:..|..:|:|:||
Worm   173 LRTVHSVLLRSPPELIEQVVMVDD---DSDK-PHLKEKLDKYVTRFNGKVIVVRTEQREGLINAR 233

  Fly   125 LTGAGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVEPEQL- 188
            ..||..:||::::||:.|.||...||||||.||..|.:.:|.|::|.|...|:.||.:......
Worm   234 SIGAKHSTGEVVLFLDAHCEVNTNWLPPLLAPIKRNRKVMTVPVIDGIDSNSWEYRSVYGSPNAH 298

  Fly   189 ---AFDWQLDHIFLPLDQ-----HSWNSLPKPYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGG 245
               .|:|.|.:....:.:     ...||  :|:.|....|.:|||:|.||..||.:||||:.:||
Worm   299 HSGIFEWGLLYKETQITERETAHRKHNS--QPFRSPTHAGGLFAINRLWFKELGYYDEGLQIWGG 361

  Fly   246 DALELSLKVWQCGGLILAVPCSRVGIIYKRDELEAQMAPNRNPSLQVQKNFKRVVDVWLDEYKLH 310
            :..|||.|:|||||.|:.||||.||.:|:.....:....:..|.:.:  |..|||..|:|:|..:
Worm   362 EQYELSFKIWQCGGGIVFVPCSHVGHVYRSHMPYSFGKFSGKPVISI--NMMRVVKTWMDDYSKY 424

  Fly   311 FYRYNPKLRNLTAESLDKPRDLRRRLNCKSFEWYRSQVAPQIRNHFLHAGLTNYPIGKIMPFVAP 375
            :....|:..|:....:.....||.:|.||||:||...||              |.:.|..|.:.|
Worm   425 YLTREPQATNVNPGDISAQLALRDKLQCKSFKWYMENVA--------------YDVLKSYPMLPP 475

  Fly   376 H------------FCLSIKGGFP---VIRKCHSTNFEDW-TLTSRCQLKHGNMCLDVDYKNNVR- 423
            :            .||...||.|   ....||....... .|..:.|:..|..||..   |.:|
Worm   476 NDVWGEARNPATGKCLDRMGGIPGPMGATGCHGYGGNQLIRLNVQGQMAQGEWCLTA---NGIRI 537

  Fly   424 -ATKCTKKLSKNPWHYNYQHSSFV-SNGNKCLQIDVNKVGLILSACDSDVTEQRWMF 478
             |..|.|......|.|:.:....: |...:|:.:..:...:.|..|..|...|::::
Worm   538 QANHCVKGTVNGFWSYDRKTKQIIHSQKRQCITVSESGSEVTLQTCTEDNERQKFVW 594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	103/300 (34%)
		pp-GalNAc-T	54..349	CDD:133004	108/311 (35%)
		RICIN	367..478	CDD:238092	28/129 (22%)
		Ricin_B_lectin	373..476	CDD:279046	26/121 (21%)
gly-7	NP_503512.1	pp-GalNAc-T	159..463	CDD:133004	108/311 (35%)
		Ricin_B_lectin	479..592	CDD:279046	25/115 (22%)
		RICIN	486..592	CDD:238092	25/108 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810