DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7579 and GALNTL5

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	XP_016867282.1	Gene:	GALNTL5 / 168391	HGNCID:	21725	Length:	496	Species:	Homo sapiens

Alignment Length:	374	Identity:	128/374 - (34%)
Similarity:	193/374 - (51%)	Gaps:	44/374 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 TETDLVDAQLQNE--KYQYNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHP 64
            |:.:..:.:|..|  ||.:|..:|..:.::|.:.|.|...||:.:|.: :..|.||||....|..
Human   137 TDFNHTNPELHKELLKYGFNVIISRSLGIEREVPDTRSKMCLQKHYPA-RLPTASIVICFYNEEC 200

  Fly    65 HTLLRGIYSVITQTSPYLLKEIVLVHDGHPDLDLIRHIHHKLPI----VIQLEMESSKGIIHARL 125
            :.|.:.:.||...|..|.|:||:||.|.....||...:.:.|..    |..:..:..:|:|.|||
Human   201 NALFQTMSSVTNLTPHYFLEEIILVDDMSKVDDLKEKLDYHLETFRGKVKIIRNKKREGLIRARL 265

  Fly   126 TGAGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVEPEQL-- 188
            .||..|:||:||||:.|.||.|.||.|||..|..:.:.|..|::|.|...:..|:    |..|
Human   266 IGASHASGDVLVFLDSHCEVNRVWLEPLLHAIAKDPKMVVCPLIDVIDDRTLEYK----PSPLVR 326

  Fly   189 -AFDWQLDHIFLPLDQHSWNSL-----------PKPYPSSQLEGRVFAIDRKWFWHLGGWDEGLR 241
             .|||.|        |..|:::           .||..|..:.|.:|||.|.:|..:|.:|:.:.
Human   327 GTFDWNL--------QFKWDNVFSYEMDGPEGSTKPIRSPAMSGGIFAIRRHYFNEIGQYDKDMD 383

  Fly   242 DYGGDALELSLKVWQCGGLILAVPCSRVGIIYKRDELEAQMAPNRNPSLQVQ---KNFKRVVDVW 303
            .:|.:.|||||::|.|||.:..:||||||.|.|:.        ...||..:.   .|:.|:|.||
Human   384 FWGRENLELSLRIWMCGGQLFIIPCSRVGHISKKQ--------TGKPSTIISAMTHNYLRLVHVW 440

  Fly   304 LDEYKLHFYRYNPKLRNLTAESLDKPRDLRRRLNCKSFEWYRSQVAPQI 352
            |||||..|:...|.|:.:|..::.:..:||:||.||||:||...|.|::
Human   441 LDEYKEQFFLRKPGLKYVTYGNIRERVELRKRLGCKSFQWYLDNVFPEL 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	105/304 (35%)
		pp-GalNAc-T	54..349	CDD:133004	112/315 (36%)
		RICIN	367..478	CDD:238092
		Ricin_B_lectin	373..476	CDD:279046
GALNTL5	XP_016867282.1	GT2	187..437	CDD:224137	91/269 (34%)
GALNTL5	XP_016867282.1	pp-GalNAc-T	190..486	CDD:133004	112/315 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152523
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740