DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7579 and Galnt4

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_056552.1	Gene:	Galnt4 / 14426	MGIID:	894692	Length:	578	Species:	Mus musculus

Alignment Length:	532	Identity:	170/532 - (31%)
Similarity:	248/532 - (46%)	Gaps:	90/532 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTETDLVDAQLQNEKYQYNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPH 65
            :.|.:|...:...|:|..|.:||:||.|.|.:||.|..:|....:......|.|::||...|...
Mouse    85 LNEGELKQQEELIERYAINIYLSDRISLHRHIEDKRMYECKAKKFHYRSLPTTSVIIAFYNEAWS 149

  Fly    66 TLLRGIYSVITQTSP-YLLKEIVLVHDGHPDLDLIRHIHHKLPIVIQLEMESS------------ 117
            ||||.|:||: :||| .|||||:||.|          :..::.:..|||...|
Mouse   150 TLLRTIHSVL-ETSPAVLLKEIILVDD----------LSDRIYLKAQLETYISNLERVRLIRTNK 203

  Fly   118 -KGIIHARLTGAGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFA-YR 180
             :|::.|||.||..||||:|.||:.|.|...|||.||||.|..:...:..|::|.|...:|. |.
Mouse   204 REGLVRARLIGATFATGDVLTFLDCHCECNTGWLEPLLERISRDETAIVCPVIDTIDWNTFEFYM 268

  Fly   181 KLVEPEQLAFDWQLDHIFLPLDQHSWNSLPK-----------PYPSSQLEGRVFAIDRKWFWHLG 234
            :..||....|||:|        ...|:|:||           |..|..:.|.:||:.:|:|.:||
Mouse   269 QTGEPMIGGFDWRL--------TFQWHSVPKHERDRRTSRIDPIRSPTMAGGLFAVSKKYFQYLG 325

  Fly   235 GWDEGLRDYGGDALELSLKVWQCGGLILAVPCSRVGIIYKRDELEAQMAPNRNPSLQVQKNFKRV 299
            .:|.|:..:||:.||||.:||||||.:...|||.||.::.:      .||...|:.  .:|..|.
Mouse   326 TYDTGMEVWGGENLELSFRVWQCGGKLEIHPCSHVGHVFPK------RAPYARPNF--LQNTARA 382

  Fly   300 VDVWLDEYKLHFYRYNPKLRNLTAESLDKPRDLRRRLNCKSFEWYRSQV-----APQIRNHFLHA 359
            .:||:||||.|||..||..|......|.:.:.||.||.||||:||...|     .|:.|..: |.
Mouse   383 AEVWMDEYKEHFYNRNPPARKEAYGDLSERKLLRERLKCKSFDWYLKNVFSNLHVPEDRPGW-HG 446

  Fly   360 GLTNYPI-GKIMPFVAPH-----FCLSIKGGFPVIRKCHSTN----FEDWTLTSRCQLKHGN--- 411
            .:.:..| .:.:.:.||.     ..||:.|       ||...    ||   .||..:::..:
Mouse   447 AIRSMGISSECLDYNAPDNNPTGANLSLFG-------CHGQGGNQFFE---YTSNKEIRFNSVTE 501

  Fly   412 MCLDV-DYKNNVRATKCTKKLSKNP----WHYNYQHSSFVSNGNKCL---QIDVNKVGLILSACD 468
            :|.:| ..|:.|....|.|.....|    ||:....:.|..:...||   :....:..:.:..||
Mouse   502 LCAEVPQQKDYVGMQNCPKDGLPVPVNIIWHFKEDGTIFHPHTRLCLSAYRTAEGRPSVHMKTCD 566

  Fly   469 SDVTEQRWMFTK 480
            :....|.|.|.|
Mouse   567 ALDKNQLWRFEK 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	113/309 (37%)
		pp-GalNAc-T	54..349	CDD:133004	121/325 (37%)
		RICIN	367..478	CDD:238092	27/130 (21%)
		Ricin_B_lectin	373..476	CDD:279046	26/122 (21%)
Galnt4	NP_056552.1	WcaA	133..430	CDD:223539	121/323 (37%)
		Catalytic subdomain A	134..243		48/119 (40%)
		pp-GalNAc-T	138..432	CDD:133004	120/320 (38%)
		Catalytic subdomain B	303..365		28/61 (46%)
		RICIN	446..576	CDD:238092	28/139 (20%)
		Ricin_B_lectin	446..574	CDD:279046	27/137 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810