Protein Alignment CG7579 and GALNT6

DIOPT Version :10

• Sequence 1: NP_648799.1
• Gene: CG7579 / 39714
• FlyBaseID: FBgn0036528
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_009141.2
• Gene: GALNT6 / 11226
• HGNCID: 4128
• Length: 622
• Species: Homo sapiens
• Alignment Length: 534
• Identity: 157/534 - (29%)
• Similarity: 240/534 - (44%)
• Gaps: 102/534 - (19%)

  Fly     7 VDAQLQNEKYQ---YNAWLSERIPLKRTL-EDYRDPQCLKINY-SSEKTVTVSIVIAIQQEHPHT 66
            ::.|.:.|.|:   :||:.|:||.|:|:| .|.|.|:|:...: ......|.|::|....|...|
Human   128 LETQEKEEGYKKHCFNAFASDRISLQRSLGPDTRPPECVDQKFRRCPPLATTSVIIVFHNEAWST 192

  Fly    67 LLRGIYSVITQTSPYLLKEIVLVHDGHPDLDLIRHIHHK-------LPIVIQLEMESSKGIIHAR 124
            |||.:|||:..|...|||||:||.|...:    .|:..|       |.:|..:..|..||:|.||
Human   193 LLRTVYSVLHTTPAILLKEIILVDDASTE----EHLKEKLEQYVKQLQVVRVVRQEERKGLITAR 253

  Fly   125 LTGAGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVEPEQL- 188
            |.||.||..::|.||:.|.|...|||.|||..|..:...|..|.:..|...:|.:.|.|:..::
Human   254 LLGASVAQAEVLTFLDAHCECFHGWLEPLLARIAEDKTVVVSPDIVTIDLNTFEFAKPVQRGRVH 318

  Fly   189 ---AFDWQLDHIFLPLDQHSWNSLP---------KPYP--SSQLEGRVFAIDRKWFWHLGGWDEG 239
               .|||.|        ...|.:||         :.||  |....|.:|:|.:.:|.|:|.:|..
Human   319 SRGNFDWSL--------TFGWETLPPHEKQRRKDETYPIKSPTFAGGLFSISKSYFEHIGTYDNQ 375

  Fly   240 LRDYGGDALELSLKVWQCGGLILAVPCSRVGIIYKRDELEAQMAPNRNP--SLQVQKNFKRVVDV 302
            :..:||:.:|:|.:||||||.:..:|||.||.:::      ..:|:..|  :..:.:|..|:.:|
Human   376 MEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFR------TKSPHTFPKGTSVIARNQVRLAEV 434

  Fly   303 WLDEYKLHFYRYNPKLRNLTAE----SLDKPRDLRRRLNCKSFEWYRSQVAPQIRNHFLHAGLTN 363
            |:|.||..|||.|.:...:..|    .:.:...||.:|:|.:|.||...|.|::
Human   435 WMDSYKKIFYRRNLQAAKMAQEKSFGDISERLQLREQLHCHNFSWYLHNVYPEM----------- 488

  Fly   364 YPIGKIMPFVAPHF-----------CLSI----KGGFPVIR-KCHSTN----FEDWTLTSRCQLK 408
                 .:|.:.|.|           ||.:    :||.|:|. .||...    ||   .|::..|:
Human   489 -----FVPDLTPTFYGAIKNLGTNQCLDVGENNRGGKPLIMYSCHGLGGNQYFE---YTTQRDLR 545

  Fly   409 HG---NMCLDVDYKNNVRATKC--TKKLSKNP----WHYNYQHSSFVSNGNKCLQIDVNKVGLIL 464
            |.   .:||.|. |..:....|  |.|.|:.|    |..........|....||.....|..  :
Human   546 HNIAKQLCLHVS-KGALGLGSCHFTGKNSQVPKDEEWELAQDQLIRNSGSGTCLTSQDKKPA--M 607

  Fly   465 SACDSDVTEQRWMF 478
            :.|:.....|.|:|
Human   608 APCNPSDPHQLWLF 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	pp-GalNAc-T	54..349	CDD:133004	105/322 (33%)
		beta-trefoil_Ricin_Pgant8-like	364..479	CDD:467339	34/144 (24%)
GALNT6	NP_009141.2	Catalytic subdomain A	176..285		46/112 (41%)
		pp-GalNAc-T	180..485	CDD:133004	105/322 (33%)
		Catalytic subdomain B	348..410		24/61 (39%)
		beta-trefoil_Ricin_GALNT6	495..622	CDD:467348	33/133 (25%)