DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7579 and Galnt16

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_001074890.1	Gene:	Galnt16 / 108760	MGIID:	1917754	Length:	558	Species:	Mus musculus

Alignment Length:	494	Identity:	145/494 - (29%)
Similarity:	233/494 - (47%)	Gaps:	61/494 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KYQYNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPHTLLRGIYSVITQTS 79
            ::.:|...|:::...|.:.|.|...|..::|||:...| |::|....|...||||.:.||:.:|.
Mouse    88 QHAFNQLESDKLSSDRPIRDTRHYSCPSLSYSSDLPAT-SVIITFHNEARSTLLRTVKSVLNRTP 151

  Fly    80 PYLLKEIVLVHDGHPD----LDLIRHIHHKLPIVIQLEMESSKGIIHARLTGAGVATGDILVFLN 140
            ..|::||:||.|...|    |.|.|     :|.|..|..:..:|:|.:|:.||.||...:|.||:
Mouse   152 ASLIQEIILVDDFSSDPEDCLLLTR-----IPKVKCLRNDKREGLIRSRVRGADVAGATVLTFLD 211

  Fly   141 GHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVEPEQLAFDWQLDHIF--LPLDQ 203
            .|.||...||.|:|:.::.::..|..||:|.||.::|||.......:..|||.|...:  :||:|
Mouse   212 SHCEVNVEWLQPMLQRVMEDHTRVVSPIIDVISLDNFAYLAASADLRGGFDWSLHFKWEQIPLEQ 276

  Fly   204 HSWNSLP-KPYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGGDALELSLKVWQCGGLILAVPCS 267
            ....:.| ||..:..:.|.:|.||:.||.|||.:|..:..:||:..|||.:||.|||.:..||||
Mouse   277 KMTRTDPTKPIRTPVIAGGIFVIDKSWFNHLGKYDAQMDIWGGENFELSFRVWMCGGSLEIVPCS 341

  Fly   268 RVGIIYKRDELEAQMAPNRNP-------SLQVQKNFKRVVDVWLDEYKLHFYRYNPKLRNLTAES 325
            |||.::::          |:|       :|...:|.||..:||:||||.::|...|........|
Mouse   342 RVGHVFRK----------RHPYNFPEGNALTYIRNTKRTAEVWMDEYKQYYYEARPSAIGKAFGS 396

  Fly   326 LDKPRDLRRRLNCKSFEWYRSQVAPQIRNHFLHAGLTNYPIGKIMPFVAPH--FCLSIKG----- 383
            :....:.|::::||||.||...|.|::          ..|:.:::|.|...  .||..:|
Mouse   397 VATRIEQRKKMDCKSFRWYLENVYPEL----------TVPVKEVLPGVIKQGVNCLESQGQNTAG 451

  Fly   384 ----GFPVIR-------KCHSTNFEDWTLTSRCQLKHGNMCLDVDYKNNVRATKCTKKLSKNPWH 437
                |..:.|       ...:..|.|..:..:.:.......|.....:.|....|..|..|..|.
Mouse   452 DLLLGMGICRGSAKSPPPAQAWLFSDHLIQQQGKCLAATSTLMSSPGSPVILQTCNPKEGKQKWR 516

  Fly   438 YNYQHSSFVSNGNKCLQIDVNKVGLILSACDSDVTEQRW 476
               :..||:.:....|.::.....|:.|.|.:|...|:|
Mouse   517 ---RKGSFIQHSVSGLCLETKPAQLVTSKCQTDAQAQQW 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	103/297 (35%)
		pp-GalNAc-T	54..349	CDD:133004	108/308 (35%)
		RICIN	367..478	CDD:238092	24/128 (19%)
		Ricin_B_lectin	373..476	CDD:279046	22/120 (18%)
Galnt16	NP_001074890.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	34..53
		Catalytic subdomain A	122..227		41/110 (37%)
		pp-GalNAc-T	126..420	CDD:133004	108/308 (35%)
		Catalytic subdomain B	286..348		28/61 (46%)
		Ricin_B_lectin	441..552	CDD:306998	21/113 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842510
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740