DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7579 and Galnt2

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_644678.2	Gene:	Galnt2 / 108148	MGIID:	894694	Length:	570	Species:	Mus musculus

Alignment Length:	492	Identity:	147/492 - (29%)
Similarity:	237/492 - (48%)	Gaps:	57/492 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 QYNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPHTLLRGIYSVITQTSPY 81
            ::|...|:::.:.|.:.|.|..||.:..:..:...| |:||....|....|||.:.||:.::.|:
Mouse   102 KFNQVESDKLHMDRGIPDTRHDQCQRKQWRVDLPAT-SVVITFHNEARSALLRTVVSVLKRSPPH 165

  Fly    82 LLKEIVLVHDGHPDLD---LIRHIHHKLPIVIQLEMESSKGIIHARLTGAGVATGDILVFLNGHM 143
            |:|||:||.|...|.:   |:    .|:..|..|..:..:|::.:|:.||..|...:|.||:.|.
Mouse   166 LIKEIILVDDYSNDPEDGALL----GKIEKVRVLRNDRREGLMRSRVRGADAAQAKVLTFLDSHC 226

  Fly   144 EVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVEPEQLAFDWQL----DHIFLPLDQH 204
            |....||.||||.:..:...|..||:|.|:.::|.|.......:..|||.|    |:: .|..:.
Mouse   227 ECNERWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDYM-TPEQRR 290

  Fly   205 SWNSLP-KPYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGGDALELSLKVWQCGGLILAVPCSR 268
            |....| .|..:..:.|.:|.:|:.:|..||.:|..:..:||:.||:|.:||||||.:..:||||
Mouse   291 SRQGNPVAPIKTPMIAGGLFVMDKLYFEELGKYDMMMDVWGGENLEISFRVWQCGGSLEIIPCSR 355

  Fly   269 VGIIYKRDELEAQMAPNRNP---SLQVQKNFKRVVDVWLDEYKLHFYRYNPKLRNLTAESLDKPR 330
            ||.::::..      |...|   .....:|.:|..:||:||||..:|...|..||:...::....
Mouse   356 VGHVFRKQH------PYTFPGGSGTVFARNTRRAAEVWMDEYKHFYYAAVPSARNVPYGNIQSRL 414

  Fly   331 DLRRRLNCKSFEWYRSQVAPQIR--NH------FLHAGLTNYPIGKIMPFVAPHFCLSIKG---- 383
            :||::|.||.|:||...|.|::|  :|      .|..| ||              ||...|
Mouse   415 ELRKKLGCKPFKWYLDNVYPELRVPDHQDIAFGALQQG-TN--------------CLDTLGHFAD 464

  Fly   384 GFPVIRKCHST-NFEDWTLTSRCQLKHGNMCLDVDYKNN---VRATKCTKKLSKNPWHYNYQHSS 444
            |...|.:||:. ..::|.||....:||.::||.|..::.   :|...|.:..|:..|.....:|.
Mouse   465 GVVGIYECHNAGGNQEWALTKEKSVKHMDLCLTVVDRSPGSLIRLQGCRENDSRQKWEQIEGNSK 529

  Fly   445 FVSNG-NKCLQIDVNKV-GLILSACDSDVTEQRWMFT 479
            ....| |.||.....|. ||.:..|...:::| |.|:
Mouse   530 LRHVGSNLCLDSRTAKSGGLSVEVCGPALSQQ-WKFS 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	95/294 (32%)
		pp-GalNAc-T	54..349	CDD:133004	100/305 (33%)
		RICIN	367..478	CDD:238092	30/120 (25%)
		Ricin_B_lectin	373..476	CDD:279046	29/112 (26%)
Galnt2	NP_644678.2	Catalytic subdomain A	134..239		38/109 (35%)
		pp-GalNAc-T	138..433	CDD:133004	100/305 (33%)
		Catalytic subdomain B	299..361		25/61 (41%)
		Ricin_B_lectin	445..562	CDD:279046	33/132 (25%)
		RICIN	455..564	CDD:238092	30/109 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810