DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7579 and galnt6.2

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	XP_031753046.1	Gene:	galnt6.2 / 100486937	XenbaseID:	XB-GENE-1000674	Length:	623	Species:	Xenopus tropicalis

Alignment Length:	532	Identity:	146/532 - (27%)
Similarity:	245/532 - (46%)	Gaps:	86/532 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 TETDLVDAQLQNEKYQYNAWLSERIPLKRTL-EDYRDPQCLKINYSSEKTV-TVSIVIAIQQEHP 64
            ||.::.:.:...:|:.:||:.|:||.|.|.| .|.|..:|::..:....:: |.||:|....|..
Frog   124 TEEEVEEKEKGFDKHCFNAFASDRISLHRALGPDTRPLECIEQKFKRCPSLPTTSIIIVFHNEAW 188

  Fly    65 HTLLRGIYSVITQTSPYLLKEIVLVHDGHPDLDLIRHIHHK-------LPIVIQLEMESSKGIIH 122
            .||||.:|||:..:...|||||:||.|...|    .::..|       |.||.....:..||:|.
Frog   189 STLLRTVYSVLYTSPAILLKEIILVDDASED----EYLKEKLDDYVKALQIVKIARQKERKGLIT 249

  Fly   123 ARLTGAGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVEPEQ 187
            |||.||.:|||::|.||:.|.|...|||.|||..:..::..|..|.:.||:..:|.:.|.|:..:
Frog   250 ARLLGASIATGEVLTFLDAHCECFHGWLEPLLSRVAEDHTAVVSPDITAINYNTFEFGKPVQQGK 314

  Fly   188 L----AFDWQLDHIFLPLDQHSWNSLP---------KPYP--SSQLEGRVFAIDRKWFWHLGGWD 237
            :    .|||.|        ..:|.::|         :.||  :....|.:|:|.:.:|.|:|.:|
Frog   315 MNSRGNFDWSL--------AFNWEAIPAADEKQRKDETYPIKTPTFAGGLFSISKAYFEHIGSYD 371

  Fly   238 EGLRDYGGDALELSLKVWQCGGLILAVPCSRVGIIYKRDELEAQMAPNRNP--SLQVQKNFKRVV 300
            |.:..:||:.:|:|.:||||||.:..:|||.||.:::      ..:|:..|  :..:.:|..|:.
Frog   372 EEMEIWGGENVEMSFRVWQCGGKLEIIPCSVVGHVFR------TKSPHTFPKGTQVILRNQVRLA 430

  Fly   301 DVWLDEYKLHFYRYNPKLRNLTAE----SLDKPRDLRRRLNCKSFEWYRSQVAPQI----RNHFL 357
            :||:|:||:.:||.|.:...:..|    .:.|...|:..|.||:|.||...:.|::    |:...
Frog   431 EVWMDDYKVLYYRRNEQAAKIAKEKSFGDISKRLKLKADLQCKNFTWYLENIYPEMFVPDRDPTY 495

  Fly   358 HAGLTNYPIGKIMPFVAPHFCLSI------KGGFPVIRKCHSTN----FEDWTLTSRCQLKHG-- 410
            :..:.|         .....|:.:      ....|::..||...    ||   .::..:|:|.
Frog   496 YGAIKN---------EGTQNCIDVGENNNYGSQLPIMYPCHGMGGNQYFE---YSTHKELRHNLK 548

  Fly   411 -NMCLDVDYK-NNVRATKC------TKKLSKNPWHYNYQHSSFVSNGNKCLQIDVNKVGLILSAC 467
             .:||...|: ..|:...|      |.......|.:...........|.||....:...  .:.|
Frog   549 TQLCLCSKYEPGPVKLVDCQYKGQNTTVPGNEEWEFTKDRLIRNVGSNMCLTAQGDHPS--TAEC 611

  Fly   468 DSDVTEQRWMFT 479
            :.|..:|.|.|:
Frog   612 NPDDIDQLWSFS 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	100/311 (32%)
		pp-GalNAc-T	54..349	CDD:133004	105/322 (33%)
		RICIN	367..478	CDD:238092	22/130 (17%)
		Ricin_B_lectin	373..476	CDD:279046	21/122 (17%)
galnt6.2	XP_031753046.1	OppC_N	1..>27	CDD:403960
		pp-GalNAc-T	178..483	CDD:133004	105/322 (33%)
		Ricin_B_lectin	496..620	CDD:395527	22/137 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910