DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7579 and Galnt6

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_001165534.1	Gene:	Galnt6 / 100361647	RGDID:	2319726	Length:	622	Species:	Rattus norvegicus

Alignment Length:	542	Identity:	157/542 - (28%)
Similarity:	239/542 - (44%)	Gaps:	110/542 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ETDLVDAQLQNEKYQ---YNAWLSERIPLKRTL-EDYRDPQCLKINY-SSEKTVTVSIVIAIQQE 62
            |..|::.|.::|.|:   :||:.|:||.|:|:| .|.|.|:|:...: ......|.|:||....|
  Rat   124 EWTLLETQEKDEGYKKHCFNAFASDRISLQRSLGPDTRPPECVDQKFRRCPPLPTTSVVIVFHNE 188

  Fly    63 HPHTLLRGIYSVITQTSPYLLKEIVLVHDGHPDLDLIRHIHHKLPIVIQ-------LEMESSKGI 120
            ...||||.:|||:..:...|||||:||.|...|    .|:..||...:|       :..:..||:
  Rat   189 AWSTLLRTVYSVLHTSPAILLKEIILVDDASTD----EHLKEKLERYVQQLQIVRVVRQQERKGL 249

  Fly   121 IHARLTGAGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVEP 185
            |.|||.||.||..::|.||:.|.|...|||.|||..|..:...|..|.:..|...:|.:.|.:..
  Rat   250 ITARLLGASVAQAEVLTFLDAHCECFHGWLEPLLARIAEDKTAVVSPDIVTIDLNTFQFSKPMRR 314

  Fly   186 EQL----AFDWQLDHIFLPLDQHSWNSLPK-----------PYPSSQLEGRVFAIDRKWFWHLGG 235
            .:.    .|||.|        ...|..||:           |..|....|.:|:|.:.:|.|:|.
  Rat   315 GKAHSRGNFDWSL--------TFGWEMLPEHEKQRRKDETYPIKSPTFAGGLFSISKAYFEHIGT 371

  Fly   236 WDEGLRDYGGDALELSLKVWQCGGLILAVPCSRVGIIYKRDELEAQMAPNRNP--SLQVQKNFKR 298
            :|..:..:||:.:|:|.:||||||.:..:|||.||.:::      ..:|:..|  :..:.:|..|
  Rat   372 YDNQMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFR------TKSPHTFPKGTSVIARNQVR 430

  Fly   299 VVDVWLDEYKLHFYRYNPKLRNLTAESLDKPRD---------LRRRLNCKSFEWYRSQVAPQIRN 354
            :.:||:|:||..|||     |||.|..:.|..:         ||.:|:|.:|.||...|.|::
  Rat   431 LAEVWMDDYKKIFYR-----RNLQAAKMAKENNFGDVSERLRLREQLHCHNFSWYLHNVYPEM-- 488

  Fly   355 HFLHAGLTNYPIGKIMPFVAPHF-----------CLSI----KGGFPVIR-KCHSTN----FEDW 399
                          .:|.:.|.|           ||.:    :||.|:|. .||:..    ||
  Rat   489 --------------FVPDLNPTFSGAIKNLGTSQCLDVGENNRGGKPLIMYVCHNLGGNQYFE-- 537

  Fly   400 TLTSRCQLKHG---NMCLDVDYKN-NVRATKCTKKLSKNP----WHYNYQHSSFVSNGNKCLQID 456
             .||:..|:|.   .:||...... .:|..:...|.|:.|    |...............||...
  Rat   538 -YTSQRDLRHNIGKQLCLHASGSTLGLRNCQFIGKNSEVPKDEEWELTQDQLIRNLGSGTCLTSK 601

  Fly   457 VNKVGLILSACDSDVTEQRWMF 478
            ..|..  ::.|:.....|.|:|
  Rat   602 DKKPA--MAPCNPSDPYQLWLF 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	102/316 (32%)
		pp-GalNAc-T	54..349	CDD:133004	106/327 (32%)
		RICIN	367..478	CDD:238092	30/138 (22%)
		Ricin_B_lectin	373..476	CDD:279046	28/130 (22%)
Galnt6	NP_001165534.1	pp-GalNAc-T	180..485	CDD:133004	106/327 (32%)
Galnt6	NP_001165534.1	Ricin_B_lectin	497..619	CDD:395527	27/126 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346002
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840