DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7579 and galnt3

DIOPT Version :9

Sequence 1:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	XP_021334717.1	Gene:	galnt3 / 100331984	ZFINID:	ZDB-GENE-120313-1	Length:	625	Species:	Danio rerio

Alignment Length:	541	Identity:	167/541 - (30%)
Similarity:	246/541 - (45%)	Gaps:	104/541 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTETDLVDAQLQNEKYQYNAWLSERIPLKRTL-EDYRDPQCLKINYSSEKTV-------TVSIVI 57
            ::.::..:.:...||:.:|.:.|:||.|.|.| .|.|.|:|:      |:|.       |.|::|
Zfish   127 LSSSEQKEKERGEEKHCFNLYASDRISLSRDLGPDTRPPECI------EQTFRRCPPLPTTSVII 185

  Fly    58 AIQQEHPHTLLRGIYSVITQTSPYL-LKEIVLVHDGHPDLDLIRHIHHKLP-------IVIQLEM 114
            ....|...||||.:|||: .|||.| ||||:||.|...|    .|:..||.       ||..:..
Zfish   186 VFHNEAWSTLLRTVYSVL-HTSPALFLKEIILVDDASVD----EHLKDKLDEFLKQLHIVRVVRQ 245

  Fly   115 ESSKGIIHARLTGAGVATGDILVFLNGHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAY 179
            ...||:|.|||.||.|||||.|.||:.|.|...|||.|||..|..|:..|..|.:..|...:|.:
Zfish   246 HERKGLITARLLGASVATGDTLTFLDAHCECFHGWLEPLLARIAENSSAVVSPDITTIDLNTFEF 310

  Fly   180 RKLVEPEQLA-------FDWQLDHIFLPLDQHSWNSLP---------KPYP--SSQLEGRVFAID 226
            .|   |....       |||.|        ...|.:||         :.||  :....|.:|:|.
Zfish   311 MK---PSPYGQHHNRGNFDWGL--------SFGWETLPDHERRRRKDETYPIKTPTFAGGLFSIS 364

  Fly   227 RKWFWHLGGWDEGLRDYGGDALELSLKVWQCGGLILAVPCSRVGIIYKRDELEAQMAPNRNP--S 289
            |.:|:|:|.:||.:..:||:.:|:|.:||||||.:..:|||.||.:::      ..:|:..|  :
Zfish   365 RDYFYHIGSYDEEMEIWGGENIEMSFRVWQCGGQLEIIPCSVVGHVFR------TKSPHTFPKGT 423

  Fly   290 LQVQKNFKRVVDVWLDEYKLHFYRYNPKLRNLTAE----SLDKPRDLRRRLNCKSFEWYRSQVAP 350
            ..:.:|..|:.:||:|:||..|||.|.:...:..|    .:.:..|||.||.||||.||...|.|
Zfish   424 QVIARNQVRLAEVWMDDYKEIFYRRNQQAAQIAKEHSFGDVSRRVDLRERLQCKSFSWYLKNVYP 488

  Fly   351 QI----RNHFLHAGLTNYPIGKIMPFVAPHFCLSI----KGGFPVIR-KCHSTN----FEDWTLT 402
            ::    .|......:.|  :||       ..||.:    :||.|:|. .||...    ||   .:
Zfish   489 EVFMPDLNPLQFGAIRN--MGK-------EACLDVGESNEGGKPLIMYPCHGMGGNQYFE---YS 541

  Fly   403 SRCQLKHG---NMCLDVDYKNNVRATKCTKK------LSKNPWHYNYQHSSFVSNGNKCLQIDVN 458
            :..:::|.   .:|||......||..:|..|      ..:..|........:.....:||.....
Zfish   542 THHEIRHNIQKELCLDGTDGAMVRLEECQYKGHNTITSPQQKWELREDQLFYNKASKQCLSARPE 606

  Fly   459 KVGLILSACDSDVTEQRWMFT 479
            ...|:  .|:.|...|.|:||
Zfish   607 NPSLV--PCNPDDKYQLWLFT 625

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	110/315 (35%)
		pp-GalNAc-T	54..349	CDD:133004	117/326 (36%)
		RICIN	367..478	CDD:238092	28/128 (22%)
		Ricin_B_lectin	373..476	CDD:279046	25/120 (21%)
galnt3	XP_021334717.1	pp-GalNAc-T	182..487	CDD:133004	117/326 (36%)
galnt3	XP_021334717.1	Ricin_B_lectin	500..622	CDD:306998	28/135 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910