Protein Alignment CG7304 and GALNT4

DIOPT Version :10

• Sequence 1: NP_996098.1
• Gene: CG7304 / 39713
• FlyBaseID: FBgn0036527
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_003765.2
• Gene: GALNT4 / 8693
• HGNCID: 4126
• Length: 578
• Species: Homo sapiens
• Alignment Length: 590
• Identity: 165/590 - (27%)
• Similarity: 257/590 - (43%)
• Gaps: 78/590 - (13%)

  Fly     9 NCCFKYIVLPVWIFIVLLL--LH-------------RDLSSWDGLMGPLSHP----------GLG 48
            :|.....:...:||:.||:  .|             |.||........||.|          .||
Human    11 SCLLLAFLTVAYIFVELLVSTFHASAGAGRARELGSRRLSDLQKNTEDLSRPLYKKPPADSRALG 75

  Fly    49 ENGSASYLSVPSWEIDEYTQGWRYYLYNSWLAERIPLRRSLPDLRDHRC--QKLEYDEDSDEMKP 111
            |.|.||.|.:...|:.:..:....|..|.:|::||.|.|.:.|.|.:.|  ||..|    ..:..
Human    76 EWGKASKLQLNEDELKQQEELIERYAINIYLSDRISLHRHIEDKRMYECKSQKFNY----RTLPT 136

  Fly   112 ASIIMIFRNEQLVVLLRTLHSLVERTPKYLYIELILVNDHSDTDFWNDKLSLIFFDNYVHRYIH- 175
            .|:|:.|.||....||||:||::|.:|..|..|:|||:|.||.         ::....:..||.
Human   137 TSVIIAFYNEAWSTLLRTIHSVLETSPAVLLKEIILVDDLSDR---------VYLKTQLETYISN 192

  Fly   176 -PKARILHLPEQVGLIKARNLAASEAKAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPILD 239
             .:.|::...::.||::||.:.|:.|..:.|.|:|...|..:|||.|||:.|......:..|::|
Human   193 LDRVRLIRTNKREGLVRARLIGATFATGDVLTFLDCHCECNSGWLEPLLERIGRDETAVVCPVID 257

  Fly   240 NLDEQTLAYQRSIERR--GMYDWSLTRR--EVP-LSRARRSHLPWPYEVAAVRTSVFAIPAVWFQ 299
            .:|..|..:...|...  |.:||.||.:  .|| ..|.||.....|.....:...:||:...:||
Human   258 TIDWNTFEFYMQIGEPMIGGFDWRLTFQWHSVPKQERDRRISRIDPIRSPTMAGGLFAVSKKYFQ 322

  Fly   300 DISNFDNNLRGFGAAELELSFKVWCTGGRIVQVPCSRVGHLQPKDEDYLKRYGDLHKMGEQKSRN 364
            .:..:|..:..:|...|||||:||..||::...|||.|||:.||...|.:         ....:|
Human   323 YLGTYDTGMEVWGGENLELSFRVWQCGGKLEIHPCSHVGHVFPKRAPYAR---------PNFLQN 378

  Fly   365 LKRIIEVWTGDLKSAIYKYQPHLLNISEGDLNEPRKLYKQNECQSFKEFINDITPGLNHVAALNR 429
            ..|..|||..:.|...|...|.....:.||::|.:.|.::..|:||..::.::.|.| ||.. :|
Human   379 TARAAEVWMDEYKEHFYNRNPPARKEAYGDISERKLLRERLRCKSFDWYLKNVFPNL-HVPE-DR 441

  Fly   430 TDYASGHVKTLEFPKKCLTINAKSQ-----NLFLERCSTNNTLQNWTLTYVKDLRV--AGNICAE 487
            ..: .|.:::.....:||..|:...     ||.|..|......|.:..|..|::|.  ...:|||
Human   442 PGW-HGAIRSRGISSECLDYNSPDNNPTGANLSLFGCHGQGGNQFFEYTSNKEIRFNSVTELCAE 505

  Fly   488 VRPNLR--LGYSFCHSLG----GRQSWHYDSVSNQLMSNT-KCLEF--TDE--LNIFLAICDAAN 541
            | |..:  :|...|...|    ....||:.........:: .||..  |.|  .::.:..|||.:
Human   506 V-PEQKNYVGMQNCPKDGFPVPANIIWHFKEDGTIFHPHSGLCLSAYRTPEGRPDVQMRTCDALD 569

  Fly   542 GKQRW 546
            ..|.|
Human   570 KNQIW 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	pp-GalNAc-T	113..417	CDD:133004	96/310 (31%)
		beta-trefoil_Ricin_Pgant8-like	432..549	CDD:467339	31/133 (23%)
GALNT4	NP_003765.2	Catalytic subdomain A	134..243		40/117 (34%)
		pp-GalNAc-T	138..432	CDD:133004	96/311 (31%)
		Catalytic subdomain B	303..365		22/61 (36%)
		beta-trefoil_Ricin_GALNT4	442..577	CDD:467347	31/135 (23%)