Protein Alignment CG7304 and Galnt1

DIOPT Version :10

• Sequence 1: NP_996098.1
• Gene: CG7304 / 39713
• FlyBaseID: FBgn0036527
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_077349.1
• Gene: Galnt1 / 79214
• RGDID: 620358
• Length: 559
• Species: Rattus norvegicus
• Alignment Length: 573
• Identity: 160/573 - (27%)
• Similarity: 282/573 - (49%)
• Gaps: 52/573 - (9%)

  Fly    12 FKY--IVLP---VWIFIVLLLL-------------HRDLSSWDGL-MGPLSHPGLGENGSASYLS 57
            |.|  :||.   ||:.:.:.||             .|.|.:.|.| :....|.|.||.|..  :.
  Rat     4 FAYCKVVLATSLVWVLLDMFLLLYFSECNKCEEKKERGLPAGDVLELVQKPHEGPGEMGKP--VV 66

  Fly    58 VPSWEIDEYTQGWRYYLYNSWLAERIPLRRSLPDLRDHRCQKLEYDEDSDEMKPASIIMIFRNEQ 122
            :|..:.::..:.::...:|...:|.|...|||||:|...|:...|   .|.:...|::::|.||.
  Rat    67 IPKEDQEKMKEMFKINQFNLMASEMIAFNRSLPDVRLEGCKTKVY---PDSLPTTSVVIVFHNEA 128

  Fly   123 LVVLLRTLHSLVERTPKYLYIELILVNDHSDTDFWNDKLSLIFFDNYVHRYIHPKARILHLPEQV 187
            ...||||:||::.|:|:::..|::||:|.|:.||....|     ::||.:...| ..::.:.::.
  Rat   129 WSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPL-----ESYVKKLKVP-VHVIRMEQRS 187

  Fly   188 GLIKARNLAASEAKAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPILDNLDEQTLAYQRSI 252
            |||:||...|:.:|.:.:.|:||..|.|.|||.|||..|.....|:..||:|.:.:.|..|....
  Rat   188 GLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAGS 252

  Fly   253 ERR-GMYDWSLTRREVPLSR----ARRSHLPWPYEVAAVRTSVFAIPAVWFQDISNFDNNLRGFG 312
            :.. |.::|.|..|..|:.:    .|:.....|.....:...:|:|...:||:|..:|..:..:|
  Rat   253 DMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWG 317

  Fly   313 AAELELSFKVWCTGGRIVQVPCSRVGHLQPKDEDYLKRYGDLHKMGEQKSRNLKRIIEVWTGDLK 377
            ...||:||::|..||.:..|.||.|||:..|...|....|    .|:..::|.:|:.|||..:.|
  Rat   318 GENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGG----TGQIINKNNRRLAEVWMDEFK 378

  Fly   378 SAIYKYQPHLLNISEGDLNEPRKLYKQNECQSFKEFINDITPGLNHVAALNRTDYASGHVKTLEF 442
            :..|...|.:..:..||::....|..:.:|:.|..::.:|.|.    :.:.|..::.|.::.:|
  Rat   379 NFFYIISPGVTKVDYGDISSRVGLRHKLQCKPFSWYLENIYPD----SQIPRHYFSLGEIRNVE- 438

  Fly   443 PKKCLTINAKSQN--LFLERCSTNNTLQNWTLTYVKDLRVAGNICAEV-RPNLRLGYSFCHSLGG 504
            ..:||...|:.:|  :.:..|......|.::.|..|::| ..::|.:| :.|..:....||.|.|
  Rat   439 TNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIR-TDDLCLDVSKLNGPVTMLKCHHLKG 502

  Fly   505 RQSWHYDSV--SNQLMSNTKCLE-FTDELNIFLAICDAANGK-QRWILDNINL 553
            .|.|.||.|  :.|.:::.:||: .|:|.:...:|.|....: |:|:|.|:.|
  Rat   503 NQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCTGSRSQQWLLRNVTL 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	pp-GalNAc-T	113..417	CDD:133004	92/308 (30%)
		beta-trefoil_Ricin_Pgant8-like	432..549	CDD:467339	32/123 (26%)
Galnt1	NP_077349.1	Catalytic subdomain A	115..225		41/115 (36%)
		pp-GalNAc-T	119..419	CDD:133004	92/309 (30%)
		Catalytic subdomain B	285..347		21/61 (34%)
		beta-trefoil_Ricin_GALNT1	426..552	CDD:467344	34/127 (27%)