DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7304 and Galntl5

DIOPT Version :9

Sequence 1:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_080725.2	Gene:	Galntl5 / 67909	MGIID:	1915159	Length:	431	Species:	Mus musculus

Alignment Length:	433	Identity:	133/433 - (30%)
Similarity:	216/433 - (49%)	Gaps:	53/433 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 YIVLPVWIFIVLLLLHRDLSSWDGLMGP----LSHPGLGENG---SASYLSVPSWEID----EYT 67
            ::.:.:|..::||.||  |...|.|...    |....||:|.   :.....|...|::    |..
Mouse    13 FLAIGLWASMLLLFLH--LEQEDMLENEKEELLKKRSLGKNAHQQTRHSEDVTHDEVNFSDPELI 75

  Fly    68 QGWRYYLYNSWLAERIPLRRSLPDLRDHRCQKLEYDEDSDEMKPASIIMIFRNEQLVVLLRTLHS 132
            ||.|.|..|:.::.|:.:.|.:||.||..||:..|..:   :..||||:.|.||:...|||.:.|
Mouse    76 QGLRRYGLNAIMSRRLGIEREVPDSRDKICQQKHYPFN---LPTASIIICFYNEEFNTLLRAVSS 137

  Fly   133 LVERTPKYLYIELILVNDHSDTDFWNDKLSLIFFDNYVHRYIHPKARILHLPEQVGLIKARNLAA 197
            :|..:|::|..|:|||:|.|:.|...|||      :|.......|.:::...::.|||:::.:.|
Mouse   138 VVNLSPQHLLEEIILVDDMSEFDDLKDKL------DYYLEIFRGKVKLIRNKKREGLIRSKMIGA 196

  Fly   198 SEAKAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPILDNLDEQTLAYQRSIERRGMYDWSL 262
            |.|..:.|||:|:..|....||.|||..||:....:..||:|.::|.||.|..:...||.:||:|
Mouse   197 SRASGDILVFLDSHCEVNRVWLEPLLHAIAKDHKMVVCPIIDVINELTLDYMAAPIVRGAFDWNL 261

  Fly   263 TRR------------EVPLSRARRSHLPWPYEVAAVRTSVFAIPAVWFQDISNFDNNLRGFGAAE 315
            ..|            |.|.:         |....|:...:|||...:|.::..:||.:...|...
Mouse   262 NLRWDNVFAYELDGPEGPST---------PIRSPAMTGGIFAINRHYFNELGQYDNGMDICGGEN 317

  Fly   316 LELSFKVWCTGGRIVQVPCSRVGHLQPKDEDYLKRYGDLHKMGEQK--SRNLKRIIEVWTGDLKS 378
            :|||.::|..||::..:||||||        |..:....|:...|.  ||||.|::.||..:.|.
Mouse   318 VELSLRIWMCGGQLFILPCSRVG--------YNSKALSQHRRANQSALSRNLLRVVHVWLDEYKG 374

  Fly   379 AIYKYQPHLLNISEGDLNEPRKLYKQNECQSFKEFINDITPGL 421
            ..:..:|.|..:|.|:::|..:|.|:..|:||:.::::|.|.|
Mouse   375 NFFLQRPSLTYVSCGNISERVELRKRLGCKSFQWYLDNIFPEL 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	44/122 (36%)
		pp-GalNAc-T	113..417	CDD:133004	100/317 (32%)
		Ricin_B_lectin	433..546	CDD:279046
		RICIN	435..548	CDD:238092
Galntl5	NP_080725.2	Catalytic subdomain A	114..224		42/115 (37%)
		pp-GalNAc-T	118..414	CDD:133004	100/318 (31%)
		Glyco_tranf_2_2	118..380	CDD:287123	90/284 (32%)
		Catalytic subdomain B	282..344		22/69 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842585
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740