Protein Alignment CG7304 and GALNT17

DIOPT Version :9

• Sequence 1: NP_996098.1
• Gene: CG7304 / 39713
• FlyBaseID: FBgn0036527
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_071924.1
• Gene: GALNT17 / 64409
• HGNCID: 16347
• Length: 598
• Species: Homo sapiens
• Alignment Length: 596
• Identity: 160/596 - (26%)
• Similarity: 252/596 - (42%)
• Gaps: 145/596 - (24%)

  Fly    27 LLHRDLSSWDGLMGPL-SHPGLGENGSASYLSVPSWEIDEYTQG-WRYYLYNSWLAERIPLRRSL 89
            :::|.|:.....:|.: .:.|.|:.|..:.|| |:.|  |..:| ...|.|||:|:|:|.|.||:
Human    73 IVYRQLNGLSKSLGLIEGYGGRGKGGLPATLS-PAEE--EKAKGPHEKYGYNSYLSEKISLDRSI 134

  Fly    90 PDLRDHRCQKLEYDEDSDEMKPASIIMIFRNEQLVVLLRTLHSLVERTPKYLYIELILVNDHSDT 154
            ||.|..:|::|:|.:|..::   |||.||.||.|.|:||::||.|..||.:|..|:|||:|:||
Human   135 PDYRPTKCKELKYSKDLPQI---SIIFIFVNEALSVILRSVHSAVNHTPTHLLKEIILVDDNSD- 195

  Fly   155 DFWNDKLSLIFFDNYVHRYIHPKARILHLPEQVGLIKARNLAASEAKAENLVFVDAQVEFTNGWL 219
               .::|. :..:.|||:......:::...::.|||:||......|..:...|.||.||||.||.
Human   196 ---EEELK-VPLEEYVHKRYPGLVKVVRNQKREGLIRARIEGWKVATGQVTGFFDAHVEFTAGWA 256

  Fly   220 SPLLDTIAEQSYTLATPILDNLDEQTLAYQRSIERRGMYDWSLTRREVPLSRARRSHLPW----- 279
            .|:|..|.|....:..|.:||:.:.....||.......|.|.|....:...:      .|
Human   257 EPVLSRIQENRKRVILPSIDNIKQDNFEVQRYENSAHGYSWELWCMYISPPK------DWWDAGD 315

  Fly   280 ---PYEVAAVRTSVFAIPAVWFQDISNFDNNLRGFGAAELELSFKVWCTGGRIVQVPCSRVGHLQ 341
               |....|:....|.:...:|.:|...|..:..:|...:||..|||..||.:..:|||||.|::
Human   316 PSLPIRTPAMIGCSFVVNRKFFGEIGLLDPGMDVYGGENIELGIKVWLCGGSMEVLPCSRVAHIE 380

  Fly   342 PKDEDYLKRYGDLHKMGEQKSRNLKRIIEVWTGDLKSAIY-KYQPHLLN--ISEGDLNEPRKLYK 403
            .|.:.|....|...|      ||..|:.|||..|.||.:| .:...|.|  |..||::|.|.|.|
Human   381 RKKKPYNSNIGFYTK------RNALRVAEVWMDDYKSHVYIAWNLPLENPGIDIGDVSERRALRK 439

  Fly   404 QNECQSFKEFINDITP------------------------------------------------- 419
            ..:|::|:.:::.:.|
Human   440 SLKCKNFQWYLDHVYPEMRRYNNTVAYGELRNNKAKDVCLDQGPLENHTAILYPCHGWGPQLARY 504

  Fly   420 ---GLNHVAALNRTDYASGHVKTLEFPKKCLTINAKSQNLFLERCSTNNTLQNWTLTYVKDLRVA 481
               |..|:.||..|        ||....:||..|:||:                 |..:.|
Human   505 TKEGFLHLGALGTT--------TLLPDTRCLVDNSKSR-----------------LPQLLD---- 540

  Fly   482 GNICAEVRPNLRLGYSFCHSLGGRQSWHYDSVSNQLMSNT---KCLEFTDE----LNIFLAICDA 539
               |.:|:.:|            .:.|::  :.|..:.|.   :|||..:.    :::.|..|..
Human   541 ---CDKVKSSL------------YKRWNF--IQNGAIMNKGTGRCLEVENRGLAGIDLILRSCTG 588

  Fly   540 ANGKQRWILDN 550
                |||.:.|
Human   589 ----QRWTIKN 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	47/122 (39%)
		pp-GalNAc-T	113..417	CDD:133004	101/314 (32%)
		Ricin_B_lectin	433..546	CDD:279046	21/119 (18%)
		RICIN	435..548	CDD:238092	23/119 (19%)
GALNT17	NP_071924.1	Catalytic subdomain A	151..262		45/118 (38%)
		pp-GalNAc-T	155..454	CDD:133004	101/315 (32%)
		Catalytic subdomain B	319..381		20/61 (33%)
		RICIN	467..593	CDD:238092	28/175 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152516
Domainoid	1	1.000	43	1.000	Domainoid score	I12402
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.740