DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7304 and galnt11

DIOPT Version :9

Sequence 1:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001070030.2	Gene:	galnt11 / 558716	ZFINID:	ZDB-GENE-060929-998	Length:	590	Species:	Danio rerio

Alignment Length:	529	Identity:	161/529 - (30%)
Similarity:	252/529 - (47%)	Gaps:	86/529 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 GWRYYLYNSWLAERIPLRRSLPDLRDHRCQKLEYDEDSDEMKPASIIMIFRNEQLVVLLRTLHSL 133
            |:..:.:|..::.|:...|.:||.|..:|:...|   |..:..|||::.|.||....||||:||:
Zfish    99 GYHKHAFNVLISNRLGYHRDVPDTRTDKCRDRAY---SVSLPTASIVICFFNEAFSALLRTVHSV 160

  Fly   134 VERTPKYLYIELILVNDHSDTDFWNDKLSLIFFDNYVHRYIHPKARILHLPEQVGLIKARNLAAS 198
            ::|||.||..|:|||:|||:.|...:.|     |:||.:::..|.:::...::.|||:.|.:.||
Zfish   161 LDRTPNYLLHEIILVDDHSELDDLKEDL-----DSYVQQHLQKKVKVVRNEKREGLIRGRMIGAS 220

  Fly   199 EAKAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPILDNLDEQTLAYQRSIERRGMYDWSLT 263
            .|..|.|||:|:..|....||.|||..|.|...|:..|::|.:...||.|..|...||.::|.|
Zfish   221 HATGEVLVFLDSHCEVNEAWLQPLLTPIKENRKTVVCPVIDIISADTLVYTPSPIVRGGFNWGL- 284

  Fly   264 RREVPLSRARRSHLPW-PYEVA-------AVRT-----SVFAIPAVWFQDISNFDNNLRGFGAAE 315
                        |..| |..::       |:|:     .:||:...:|.::..:|..:..:|...
Zfish   285 ------------HFKWDPVPMSELNSPDGAIRSPTMAGGLFAMDRNYFYELGQYDRGMDIWGGEN 337

  Fly   316 LELSFKVWCTGGRIVQVPCSRVGHLQPKDEDYLKRYGDLHKMGEQKSRNLKRIIEVWTGDLKSAI 380
            ||:||::|..||:::.||||||||:..|...|....|.     :..:.|..|:..||..|.|...
Zfish   338 LEISFRIWMCGGQLLIVPCSRVGHIFRKRRPYGSPGGQ-----DTMAHNSLRLAHVWMDDYKEQY 397

  Fly   381 YKYQPHLLNISEGDLNEPRKLYKQNECQSFKEFINDITP------------------GLNHVAAL 427
            :..:|.|.|...||::|...:.|:.:|.|||.::::|.|                  ||.....|
Zfish   398 FALRPELRNRDYGDISERVSIRKRLQCHSFKWYLDNIYPEMQVSSPHKPQQPVFINKGLKRPKVL 462

  Fly   428 NRTDYASGHVKTLEFPKKCLTINAK-SQN---LFLERCSTNNTLQNWTLTYVKDLRVAGNIC--- 485
            .|     |.::.| ...|||....: ||.   :.::.|...:..|.|......:|.:||.:|
Zfish   463 QR-----GRLRNL-LADKCLVAQGRPSQKGGAVVVKDCDPQDPEQEWAYDEEHELVLAGLLCLDM 521

  Fly   486 AEVR----PNLRLGYSFCHSLGGRQSWHYDSVSNQL--MSNTKCLEFTDELNI----FLAICDAA 540
            :|:|    |.|..    ||..||.|.|.... .|.|  :|..:||...|.|:|    .:||||.:
Zfish   522 SEIRSSDPPRLMK----CHGSGGSQQWTLGK-KNWLYQVSVGQCLAVGDPLSIKGYVSMAICDDS 581

  Fly   541 NGKQRWILD 549
            . .|:|.|:
Zfish   582 R-SQQWQLE 589

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	50/122 (41%)
		pp-GalNAc-T	113..417	CDD:133004	105/316 (33%)
		Ricin_B_lectin	433..546	CDD:279046	37/129 (29%)
		RICIN	435..548	CDD:238092	38/129 (29%)
galnt11	NP_001070030.2	GT2	135..468	CDD:224137	113/360 (31%)
		pp-GalNAc-T	140..435	CDD:133004	105/317 (33%)
		Ricin_B_lectin	465..586	CDD:279046	37/127 (29%)
		RICIN	465..586	CDD:238092	37/127 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810