DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7304 and galnt13

DIOPT Version :9

Sequence 1:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	XP_031748551.1	Gene:	galnt13 / 550031	XenbaseID:	XB-GENE-1012445	Length:	571	Species:	Xenopus tropicalis

Alignment Length:	561	Identity:	162/561 - (28%)
Similarity:	275/561 - (49%)	Gaps:	53/561 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 VWIFI-VLLLLH----------RDLSSWDGLMGPLSH--PGLGENGSASYLSVPSWEIDEYTQGW 70
            ||:.: |.|||:          :|.|....|...:|.  .|.||.|.|  :.:|..:.::..:.:
Frog    16 VWVLLDVFLLLYFSECNKCDDRKDRSLLPALRAVISRTPEGPGELGKA--VIIPKDDQEKMKELF 78

  Fly    71 RYYLYNSWLAERIPLRRSLPDLRDHRCQKLEYDEDSDEMKPASIIMIFRNEQLVVLLRTLHSLVE 135
            :...:|...::.|.|.|||||:|...|:...|   .||:...||:::|.||....||||:||::.
Frog    79 KINQFNLMASDLIALNRSLPDVRLEGCKTKVY---PDELPNTSIVIVFHNEAWSTLLRTVHSVIN 140

  Fly   136 RTPKYLYIELILVNDHSDTDFWNDKLSLIFFDNYVHRYIHPKARILHLPEQVGLIKARNLAASEA 200
            |:|..|..|:|||:|.|:.||....|     :||| :::....:||.:.::.|||:||...|:.|
Frog   141 RSPHRLISEIILVDDSSERDFLKSPL-----ENYV-KHLEVPVKILRMEQRSGLIRARLRGANVA 199

  Fly   201 KAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPILDNLDEQTLAYQRSIERR-GMYDWSLTR 264
            |.:.:.|:||..|.|.|||.|||..|.|...|:..||:|.:.:.|..|....:.. |.::|.|..
Frog   200 KGQIITFLDAHCECTIGWLEPLLARIKEDRKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNF 264

  Fly   265 REVPLSR----ARRSHLPWPYEVAAVRTSVFAIPAVWFQDISNFDNNLRGFGAAELELSFKVWCT 325
            |..|:.:    .|:.....|.....:...:|:|...:|:::..:|:.:..:|...||:||::|..
Frog   265 RWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDKTYFEELGTYDSGMDIWGGENLEMSFRIWQC 329

  Fly   326 GGRIVQVPCSRVGHLQPKDEDYLKRYGDLHKMGEQKSRNLKRIIEVWTGDLKSAIYKYQPHLLNI 390
            ||.:..|.||.|||:..|...|....|..|.:    ::|.:|:.|||..|.|...|...|.::.:
Frog   330 GGSLEIVTCSHVGHVFRKATPYTFPGGTGHVI----NKNNRRLAEVWMDDFKDFFYIISPGVVKV 390

  Fly   391 SEGDLNEPRKLYKQNECQSFKEFINDITPGLNHVAALNRTDYASGHVKTLEFPKKCLTINAKSQN 455
            ..||::|.:.|.:..:|..|..::..:.|.    :.:.|..::.|.::.:| ..:||....:.:|
Frog   391 DYGDVSERKALRENLKCNPFSWYLETVYPD----SQIPRRYFSLGEIRNVE-TNQCLDNMGRKEN 450

  Fly   456 --LFLERCSTNNTLQNWTLTYVKDLRVAGNICAEVR----PNLRLGYSFCHSLGGRQSWHYDSVS 514
              :.:..|......|.::.|..|::| ..::|.:|.    |.:.|.   ||.:.|.|.|.||:.:
Frog   451 EKVGIFNCHGMGGNQVFSYTADKEIR-TDDLCLDVSRLNGPVIMLK---CHHMRGNQLWEYDAET 511

  Fly   515 NQLMS--NTKCLEFTD-ELNIFLAICDAANGK--QRWILDN 550
            :..:.  ...||..:: |...|....:..||:  |||.|.|
Frog   512 HTFLHIITQSCLTLSNVEDGTFGPTVEFCNGRNQQRWTLRN 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	50/122 (41%)
		pp-GalNAc-T	113..417	CDD:133004	99/308 (32%)
		Ricin_B_lectin	433..546	CDD:279046	28/123 (23%)
		RICIN	435..548	CDD:238092	30/123 (24%)
galnt13	XP_031748551.1	pp-GalNAc-T	118..418	CDD:133004	99/309 (32%)
galnt13	XP_031748551.1	Ricin_B_lectin	431..548	CDD:395527	28/121 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910