DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7304 and galnt11

DIOPT Version :9

Sequence 1:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	XP_031759178.1	Gene:	galnt11 / 448751	XenbaseID:	XB-GENE-981830	Length:	601	Species:	Xenopus tropicalis

Alignment Length:	576	Identity:	161/576 - (27%)
Similarity:	261/576 - (45%)	Gaps:	102/576 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 MGPLSHPGLGENGS----------ASYLSVPSWEIDEYTQ--GWRYYLYNSWLAERIPLRRSLPD 91
            ||..|.|..|.||:          :..|.:...|.|:..:  |::.:.:|..::.|:...|.:||
Frog    64 MGQHSDPRKGHNGNQLETEANADLSPELGMIFNEQDQDVRDVGYQKHAFNLLISNRLGYHRDVPD 128

  Fly    92 LRDHRCQKLEYDEDSDEMKPASIIMIFRNEQLVVLLRTLHSLVERTPKYLYIELILVNDHSDTDF 156
            .||.:|.|..|..|   :..|||::.|.||....||||:||:::|||..|..|:|||:|:|:.|.
Frog   129 TRDSKCAKKTYPPD---LPMASIVICFYNEAFSALLRTVHSVLDRTPAQLLHEIILVDDNSELDD 190

  Fly   157 WNDKLSLIFFDNYVHRYIHPKARILHLPEQVGLIKARNLAASEAKAENLVFVDAQVEFTNGWLSP 221
            ....|     |.|:...:..|.:::...::.|||:.|.:.||.|..:.|||:|:..|....||.|
Frog   191 LKKDL-----DGYMQENLSKKVKLVRNKQREGLIRGRMVGASHATGDVLVFLDSHCEVNEMWLQP 250

  Fly   222 LLDTIAEQSYTLATPILDNLDEQTLAYQRSIERRGMYDWSLTRREVPLSRARRSHLPW------- 279
            ||..|.|...|:..|::|.:...||.|..|...||.::|.|             |..|
Frog   251 LLAPIKENPRTVVCPVIDIISADTLIYSSSPVVRGGFNWGL-------------HFKWDPVPLAE 302

  Fly   280 ---------PYEVAAVRTSVFAIPAVWFQDISNFDNNLRGFGAAELELSFKVWCTGGRIVQVPCS 335
                     |:....:...:||:...:|..:..:|:.:..:|...||:||::|..||.::.||||
Frog   303 LGGPEGFSAPFRSPTMAGGLFAMDREYFNMLGQYDSGMDIWGGENLEISFRIWMCGGSLLIVPCS 367

  Fly   336 RVGHLQPKDEDYLKRYGDLHKMGEQKSRNLKRIIEVWTGDLKSAIYKYQPHLLNISEGDLNEPRK 400
            ||||:..|...|....|.     :..:.|..|:..||..:.|...:..:|.|.|...||:.|...
Frog   368 RVGHIFRKRRPYGSPGGH-----DTMAHNSLRLAHVWMDEYKDQYFALRPELRNRDFGDIRERLA 427

  Fly   401 LYKQNECQSFKEFINDITP-------------------GLNHVAALNRTDYASGHVKTLEFPKKC 446
            |.::..|:|||.::::|.|                   |......|.|     |.:..:: ..:|
Frog   428 LRRRLNCKSFKWYLDNIYPEMQVSGPNAKPQPPVFMNKGQKRPKILQR-----GRLINMQ-TNRC 486

  Fly   447 LTI----NAKSQNLFLERCSTNNTLQNWTLTYVKDLRVAGNIC---AEVR----PNLRLGYSFCH 500
            |..    :.|...:..:.|..|::.|.|:.....:|.::..:|   :|.|    |.|..    ||
Frog   487 LVAQGHPSQKGGLVVAKECDYNDSEQVWSYNEEHELILSNLLCLDMSETRSSDPPRLMK----CH 547

  Fly   501 SLGGRQSWHYDSVSNQL--MSNTKCLEFTDELN----IFLAICDAANGKQRWILDN 550
            ..||.|.|.:.. ||:|  :|..:||:..|.::    :.:|||| .:..|:|.|:|
Frog   548 GSGGSQQWVFGK-SNRLYQVSVGQCLKLVDPMSRKGYVSMAICD-GSPSQQWHLEN 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	46/122 (38%)
		pp-GalNAc-T	113..417	CDD:133004	98/319 (31%)
		Ricin_B_lectin	433..546	CDD:279046	32/129 (25%)
		RICIN	435..548	CDD:238092	33/129 (26%)
galnt11	XP_031759178.1	pp-GalNAc-T	147..445	CDD:133004	98/320 (31%)
galnt11	XP_031759178.1	Ricin_B_lectin	476..597	CDD:395527	32/127 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910