DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7304 and Pgant1

DIOPT Version :9

Sequence 1:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_611043.1	Gene:	Pgant1 / 36717	FlyBaseID:	FBgn0034025	Length:	601	Species:	Drosophila melanogaster

Alignment Length:	551	Identity:	160/551 - (29%)
Similarity:	244/551 - (44%)	Gaps:	84/551 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 GLGENGSASYLSVPSWEI-DEYTQGWRYYLYNSWLAERIPLRRSLPDLRDHRCQKLEYDEDSDEM 109
            ||||.|.|.:||..:.|. ||.   ::....|..|:|::...||:.|.|:..|.|..:  |||.:
  Fly    89 GLGEQGVAVHLSGAAKERGDEI---YKKIALNEELSEQLTYNRSVGDHRNPLCAKQRF--DSDSL 148

  Fly   110 KPASIIMIFRNEQLVVLLRTLHSLVERTPKYLYIELILVNDHSDTDFWNDKLSLIFFDNYVH-RY 173
            ..||:::||.||...|||||:||.:....:....|:|||:|.||......||     |.||. |.
  Fly   149 PTASVVIIFFNEPYSVLLRTVHSTLSTCNEKALKEIILVDDGSDNVELGAKL-----DYYVRTRI 208

  Fly   174 IHPKARILHLPEQVGLIKARNLAASEAKAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPIL 238
            ...|..||.|..::|||:||...|..|..:.|:|:||..|...||..|||..|.|...::..||:
  Fly   209 PSGKVTILRLKNRLGLIRARLAGARIATGDVLIFLDAHCEGNIGWCEPLLQRIKESRTSVLVPII 273

  Fly   239 DNLDEQTLAYQRS---------IERRGMYDW-SLTRREVPLSR--ARRSHLPWPYEVAAVRTSVF 291
            |.:|.....|..:         .:..|.:|| :|..||....|  .::.....|.....:...:|
  Fly   274 DVIDANDFQYSTNGYKSFQVGGFQWNGHFDWINLPEREKQRQRRECKQEREICPAYSPTMAGGLF 338

  Fly   292 AIPAVWFQDISNFDNNLRGFGAAELELSFKVWCTGGRIVQVPCSRVGHLQPKDEDYLKRYGDLHK 356
            ||...:|.::.::|..:.|:|...||:||::|..||.|..:|||||||:          :.|.|.
  Fly   339 AIDRRYFWEVGSYDEQMDGWGGENLEMSFRIWQCGGTIETIPCSRVGHI----------FRDFHP 393

  Fly   357 MGEQKSR-----NLKRIIEVWTGDLKSAIYKYQPHL-LNISEGDLNEPRKLYKQNECQSFKEFIN 415
            ......|     |..|:..||..:..:..:..:|.| .:...||:.....|.|:..|:||:.::.
  Fly   394 YKFPNDRDTHGINTARMALVWMDEYINIFFLNRPDLKFHADIGDVTHRVMLRKKLRCKSFEWYLK 458

  Fly   416 DITP----------GLNHVAALNRTDYASGHVKTLEFPKK-----CLTINAKSQNLFLERCSTNN 465
            :|.|          |...|.|:|........::..|.|..     |..:..|||   |...:..|
  Fly   459 NIYPEKFVPTKDVQGWGKVHAVNSNICLDDLLQNNEKPYNAGLYPCGKVLQKSQ---LFSFTNTN 520

  Fly   466 TLQNWTLTYVKDLRVAGNICAEVR----PNLRLGYSFC-HSLGGRQSWHYDSVSNQLMSNT-KCL 524
            .|:|       :|.     ||.|:    |..|:....| .:....:.|.|:. .:.:.||| .||
  Fly   521 VLRN-------ELS-----CATVQHSESPPYRVVMVPCMENDEFNEQWRYEH-QHIIHSNTGMCL 572

  Fly   525 EF-----TDELNIFLAICDAANGKQRWILDN 550
            :.     .|:..:  |.||..:..|||.:::
  Fly   573 DHQGLKSLDDAQV--APCDPHSESQRWTIEH 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	49/123 (40%)
		pp-GalNAc-T	113..417	CDD:133004	99/322 (31%)
		Ricin_B_lectin	433..546	CDD:279046	29/128 (23%)
		RICIN	435..548	CDD:238092	31/128 (24%)
Pgant1	NP_611043.1	WcaA	147..426	CDD:223539	91/293 (31%)
		pp-GalNAc-T	152..461	CDD:133004	99/323 (31%)
		Ricin_B_lectin	474..597	CDD:279046	32/140 (23%)
		RICIN	481..599	CDD:238092	32/135 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910