DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7304 and Galnt3

DIOPT Version :9

Sequence 1:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001015032.2	Gene:	Galnt3 / 366061	RGDID:	1306443	Length:	633	Species:	Rattus norvegicus

Alignment Length:	526	Identity:	152/526 - (28%)
Similarity:	248/526 - (47%)	Gaps:	81/526 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 PGL-GENGSASYLSVPSWEIDEYTQGWRYYLYNSWLAERIPLRRSL-PDLRDHRCQKLEYDEDSD 107
            ||. |:....::|| |. |..|..:|...:.:|::.::||.|.|.| ||.|...|.:.:: :...
  Rat   121 PGASGKPFKITHLS-PE-EQKEKERGETKHCFNAFASDRISLHRDLGPDTRPPECIEQKF-KRCP 182

  Fly   108 EMKPASIIMIFRNEQLVVLLRTLHSLVERTPKYLYIELILVNDHSDTDFWNDKLSLIFFDNYVHR 172
            .:...|:|::|.||....||||:||::..:|..|..|:|||:|.|..|:.::||     :.|:.:
  Rat   183 PLPTTSVIIVFHNEAWSTLLRTVHSVLYSSPAILLKEIILVDDASVDDYLHEKL-----EEYIKQ 242

  Fly   173 YIHPKARILHLPEQVGLIKARNLAASEAKAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPI 237
            :  ...:|:...|:.|||.||.|.|:.|.||.|.|:||..|...|||.|||..|||....:.:|.
  Rat   243 F--SIVKIVRQQERKGLITARLLGAAVATAETLTFLDAHCECFYGWLEPLLARIAENYTAVVSPD 305

  Fly   238 LDNLDEQTLAYQR-----SIERRGMYDWSLTRREVPL---SRARRSHLPWPYEVAAVRTSVFAIP 294
            :.::|..|..:.:     |...||.:||||:.....|   .:.||....:|.:.......:|:|.
  Rat   306 IASIDLNTFEFNKPSPYGSNHNRGNFDWSLSFGWESLPDHEKQRRKDETYPIKTPTFAGGLFSIS 370

  Fly   295 AVWFQDISNFDNNLRGFGAAELELSFKVWCTGGRIVQVPCSRVGHLQPKDEDYLKRYGDLHKMGE 359
            ..:|:.|.::|..:..:|...:|:||:||..||::..:|||.|||:      :..:.......|.
  Rat   371 RDYFEHIGSYDEEMEIWGGENIEMSFRVWQCGGQLEIMPCSVVGHV------FRSKSPHTFPKGT 429

  Fly   360 QK-SRNLKRIIEVWTGDLKSAIYKYQPHLLNI----SEGDLNEPRKLYKQNECQSFKEFINDITP 419
            |. :||..|:.|||..:.|...|:.......|    |.|||::..::.|:.:|::|..::|.|.|
  Rat   430 QVIARNQVRLAEVWMDEYKEIFYRRNTDAAKIVKQKSFGDLSKRFEIKKRLQCKNFTWYLNTIYP 494

  Fly   420 GLNHVAALNRTDYASGHVKTLEFPKKCLTINAKSQNLFLERCSTNNTLQNWTLTYVKDLRVAGNI 484
            .: :|..||  ...||::|::..| .||.:...:|.        :..|..:|
  Rat   495 EV-YVPDLN--PVISGYIKSVGQP-LCLDVGENNQG--------DKPLILYT------------- 534

  Fly   485 CAEVRPNLRLGYSFCHSLGGRQSWHYDSVSNQLMSNTK---CLEFTDELNIFLAIC------DAA 540
                          ||.|||.|.:.| |...::..|.:   ||..|..: :.|..|      ..|
  Rat   535 --------------CHGLGGNQYFEY-SAQREIRHNIQKELCLHATQGV-VQLKACVYKGHRTIA 583

  Fly   541 NGKQRW 546
            .|:|.|
  Rat   584 PGEQIW 589

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	49/122 (40%)
		pp-GalNAc-T	113..417	CDD:133004	101/316 (32%)
		Ricin_B_lectin	433..546	CDD:279046	26/121 (21%)
		RICIN	435..548	CDD:238092	26/121 (21%)
Galnt3	NP_001015032.2	pp-GalNAc-T	188..493	CDD:133004	101/317 (32%)
		Ricin_B_lectin	506..627	CDD:279046	27/122 (22%)
		RICIN	507..629	CDD:238092	26/121 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900