DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7304 and Galnt16

DIOPT Version :9

Sequence 1:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001094333.1	Gene:	Galnt16 / 362760	RGDID:	1310202	Length:	558	Species:	Rattus norvegicus

Alignment Length:	524	Identity:	143/524 - (27%)
Similarity:	223/524 - (42%)	Gaps:	83/524 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 PLSHPGLGENG--SASYLSVPSWEIDEYTQGWRYYLYNSWLAERIPLRRSLPDLRDHRCQKLEYD 103
            ||...|....|  ..:|||....:..|  ..:|.:.:|...::::...|.:.|.|.:.|..|.|
  Rat    57 PLIVTGTPSKGFDEKAYLSAKQLKPGE--DPYRQHAFNQLESDKLSPDRPIRDTRHYSCPSLSY- 118

  Fly   104 EDSDEMKPASIIMIFRNEQLVVLLRTLHSLVERTPKYLYIELILVNDHSDTDFWNDKLSLIFFDN 168
              |.::...|:|:.|.||....||||:.|::.|||..|..|:|||:|.|...  .|.|.|...
  Rat   119 --SSDLPATSVIITFHNEARSTLLRTVKSVLNRTPAGLIQEIILVDDFSSDP--EDCLLLTRI-- 177

  Fly   169 YVHRYIHPKARILHLPEQVGLIKARNLAASEAKAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTL 233
                   ||.:.|...::.|||::|...|..|.|..|.|:|:..|....||.|:|..:.|....:
  Rat   178 -------PKVKCLRNDKREGLIRSRVRGADVAGASVLTFLDSHCEVNVEWLQPMLQRVMEDHTRV 235

  Fly   234 ATPILDNLDEQTLAY-QRSIERRGMYDWSLTRR--EVPL-SRARRSHLPWPYEVAAVRTSVFAIP 294
            .:||:|.:.....|| ..|.:.||.:||||..:  ::|| .:..|:....|.....:...:|.|.
  Rat   236 VSPIIDVISLDNFAYLAASADLRGGFDWSLHFKWEQIPLEQKMTRTDPTKPIRTPVIAGGIFVID 300

  Fly   295 AVWFQDISNFDNNLRGFGAAELELSFKVWCTGGRIVQVPCSRVGHLQPKDEDYLKRYGDLHKMGE 359
            ..||..:..:|..:..:|....||||:||..||.:..||||||||:      :.||:......|.
  Rat   301 KSWFNHLGKYDAQMDIWGGENFELSFRVWMCGGSLEIVPCSRVGHV------FRKRHPYNFPEGN 359

  Fly   360 QKS--RNLKRIIEVWTGDLKSAIYKYQPHLLNISEGDLNEPRKLYKQNECQSFKEFINDITPGLN 422
            ..:  ||.||..|||..:.|...|:.:|..:..:.|.:....:..|:.:|:||:.::.::.|.|
  Rat   360 ALTYIRNTKRTAEVWMDEYKQYYYEARPSAIGKAFGSVATRIEQRKKMDCKSFRWYLENVYPEL- 423

  Fly   423 HVAALNRTDYASGHVKTLEFPKKCLTINAKSQNLFLERCSTNNTLQNWTLTYVKDLRVAGNICAE 487
               .:...:...|.:|.   ...||  .::.||                        .||
  Rat   424 ---TVPVKEVLPGVIKQ---GVNCL--ESQGQN------------------------TAG----- 451

  Fly   488 VRPNLRLGYSFCH----SLGGRQSWHYDSVSNQLMSNTKCLEFTDEL------NIFLAICDAANG 542
               :|.||...|.    |....|:|.:.  .:.:....|||..|..|      .:.|..|:...|
  Rat   452 ---DLLLGMGICRGSAKSPPPAQAWLFS--DHLIQQQGKCLAATSTLMSSPGSPVVLQSCNPKEG 511

  Fly   543 KQRW 546
            ||:|
  Rat   512 KQKW 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	42/122 (34%)
		pp-GalNAc-T	113..417	CDD:133004	98/309 (32%)
		Ricin_B_lectin	433..546	CDD:279046	25/122 (20%)
		RICIN	435..548	CDD:238092	26/122 (21%)
Galnt16	NP_001094333.1	pp-GalNAc-T	126..420	CDD:133004	98/310 (32%)
		WcaA	126..>222	CDD:223539	38/106 (36%)
		Ricin_B_lectin	441..543	CDD:279046	24/111 (22%)
		RICIN	441..543	CDD:238092	24/111 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345962
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740