DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7304 and Pgant2

DIOPT Version :9

Sequence 1:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_608773.2	Gene:	Pgant2 / 33556	FlyBaseID:	FBgn0031530	Length:	633	Species:	Drosophila melanogaster

Alignment Length:	485	Identity:	137/485 - (28%)
Similarity:	220/485 - (45%)	Gaps:	74/485 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 YNSWLAERIPLRRSLPDLRDHRCQKLEYDEDSDEMKPASIIMIFRNEQLVVLLRTLHSLVERTPK 139
            :|...::.:|..|.:||.|:..|:..:|.||..|   .|:|:.|.||....||||:.|::.|:|:
  Fly   170 FNQEASDALPSNRDIPDTRNPMCRTKKYREDLPE---TSVIITFHNEARSTLLRTIVSVLNRSPE 231

  Fly   140 YLYIELILVNDHSDTDFWNDKLSLIFFDNYVHRYIHPKARILHLPEQVGLIKARNLAASEAKAEN 204
            :|..|::||:|:||..  .|.|.|...|         |.|::...::.||:::|...|..|.:..
  Fly   232 HLIREIVLVDDYSDHP--EDGLELAKID---------KVRVIRNDKREGLVRSRVKGADAAVSSV 285

  Fly   205 LVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPILDNLDEQTLAY-QRSIERRGMYDWSLTRR--- 265
            |.|:|:.||....||.|||:.:.|....:..|::|.:......| ..|.:.||.:||:|..:
  Fly   286 LTFLDSHVECNEMWLEPLLERVREDPTRVVCPVIDVISMDNFQYIGASADLRGGFDWNLIFKWEY 350

  Fly   266 EVPLSRARRSHLPWPYEVAAVRT-----SVFAIPAVWFQDISNFDNNLRGFGAAELELSFKVWCT 325
            ..|..||.|.:.|    ..|:||     .:|.|...:|..:..:|..:..:|...||:||:||..
  Fly   351 LSPSERAMRHNDP----TTAIRTPMIAGGLFVIDKAYFNKLGKYDMKMDVWGGENLEISFRVWQC 411

  Fly   326 GGRIVQVPCSRVGHLQPKDEDYLKRYGDLHKMGEQKSRNLKRIIEVWTGDLKSAIYKYQPHLLNI 390
            ||.:..:|||||||:..|...|....|.    |...:||.:|..|||..|.|...|...|...||
  Fly   412 GGSLEIIPCSRVGHVFRKRHPYTFPGGS----GNVFARNTRRAAEVWMDDYKQHYYNAVPLAKNI 472

  Fly   391 SEGDLNEPRKLYKQNECQSFKEFINDITPGLN----HVAALNRTDYAS-----GHV--------- 437
            ..|::::...|.::..|:.||.::.::.|.|.    ......|.|...     ||:
  Fly   473 PFGNIDDRLALKEKLHCKPFKWYLENVYPDLQAPDPQEVGQFRQDSTECLDTMGHLIDGTVGIFP 537

  Fly   438 -------KTLEFPKK--------CLTI--NAKSQNLFLERCSTNNTLQNWTLT---YVKDLRVAG 482
                   :...|.|:        |||:  .|:...:.|:.|..:.. |.|.:.   .|:..::
  Fly   538 CHNTGGNQEWAFTKRGEIKHDDLCLTLVTFARGSQVVLKACDDSEN-QRWIMREGGLVRHYKI-- 599

  Fly   483 NICAEVRPNLRLGYS--FCHSLGGRQSWHY 510
            |:|.:.|...:.|.|  .|:|..|.|.|.:
  Fly   600 NVCLDSRDQSQQGVSAQHCNSALGTQRWSF 629

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	42/122 (34%)
		pp-GalNAc-T	113..417	CDD:133004	99/312 (32%)
		Ricin_B_lectin	433..546	CDD:279046	23/114 (20%)
		RICIN	435..548	CDD:238092	23/107 (21%)
Pgant2	NP_608773.2	WcaA	200..>432	CDD:223539	81/249 (33%)
		pp-GalNAc-T	205..500	CDD:133004	99/313 (32%)
		Ricin_B_lectin	511..627	CDD:279046	24/118 (20%)
		RICIN	513..629	CDD:238092	25/118 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457054
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840