DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7304 and Galnt9

DIOPT Version :9

Sequence 1:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001116116.1	Gene:	Galnt9 / 304571	RGDID:	1311523	Length:	604	Species:	Rattus norvegicus

Alignment Length:	561	Identity:	162/561 - (28%)
Similarity:	251/561 - (44%)	Gaps:	89/561 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 DGLMGPL----SHPGLGENGSASYLSVPSWEIDEYTQG-WRYYLYNSWLAERIPLRRSLPDLRDH 95
            :||..|:    ...|||:.|.|:.|...|.|    |:| :..:.||:.|::||.|.|::||.|..
  Rat    80 NGLAKPIGLVEGPGGLGQGGVAATLQDDSQE----TEGKFEDFGYNAQLSDRISLDRTIPDYRPK 140

  Fly    96 RCQKLEYDEDSDEMKPASIIMIFRNEQLVVLLRTLHSLVERTPKYLYIELILVNDHSDTDFWNDK 160
            ||:::.|.||..::   |::.||.||.|.|:||::||:|..||..|..|:|||:|:|      |.
  Rat   141 RCRQITYSEDLPQI---SVVFIFVNEALSVILRSVHSVVNHTPSQLLKEIILVDDNS------DN 196

  Fly   161 LSLIF-FDNYVHRYIHPKARILHLPEQVGLIKARNLAASEAKAENLVFVDAQVEFTNGWLSPLLD 224
            :.|.| .|.|||:......:::....:.|||:||......|.|..:.|.||.|||..||..|.|.
  Rat   197 VELKFNLDQYVHKRYPGLVKVVRNSRREGLIRARLQGWKVATAPIVGFFDAHVEFNTGWAEPALA 261

  Fly   225 TIAEQSYTLATPILDNLDEQTLAYQRSIERRGMYDWSLTRREV--PLSRARRSHLPWPYEVAAVR 287
            .|.|....:..|.:||:...|...|:.......|:|.|....:  |.....|.....|....|:.
  Rat   262 RIQEDRRRIILPAIDNIKYSTFEVQQYASAAHGYNWGLWCMYIIPPQDWLDRGDESAPIRTPAMI 326

  Fly   288 TSVFAIPAVWFQDISNFDNNLRGFGAAELELSFKVWCTGGRIVQVPCSRVGHLQ------PKDED 346
            ...|.:...:|.||...|..:..:||..:||..:||..||.:..:|||||.|::      ..|.|
  Rat   327 GCSFVVDREYFGDIGLLDPGMEVYGAENIELGMRVWQCGGSMEVLPCSRVAHIERTKKPYNNDID 391

  Fly   347 YLKRYGDLHKMGEQKSRNLKRIIEVWTGDLKSAIY-KYQPHLLN--ISEGDLNEPRKLYKQNECQ 408
            |..:            ||..|..|||..|.||.:| .:...:.|  :..||::|...|.::.:|:
  Rat   392 YYAK------------RNALRAAEVWMDDFKSHVYMAWNIPMTNPGVDFGDVSERLALRQKLKCR 444

  Fly   409 SFKEFINDITPGLNHVAALNRTDYASGHVKTLEFPKKCLTINAKSQN---LF--------LERCS 462
            |||.::.::.|   .:...|.| ...|.|:..:....||...|:..:   |:        |.|.|
  Rat   445 SFKWYLENVYP---EMRIYNNT-LTYGEVRNSKASGYCLDQGAEDDDRAILYPCHGMSSQLVRYS 505

  Fly   463 TNNTLQNWTL---TYVKDLRV-----AGNI-----CAEV-RPNLRLGYSFCHSLGGRQSWHYDSV 513
            .:..||...|   .::.|.:.     .|.:     |.:| ||..||             |.: :.
  Rat   506 ADGLLQLGPLGSTAFLPDSKCLVDDGRGRMPTLKKCEDVARPTQRL-------------WDF-TQ 556

  Fly   514 SNQLMSNT--KCL--EFTDELNIFLAICDAANGKQRWILDN 550
            |..::|..  :||  |.:.:.|..|.:.......|:|::.|
  Rat   557 SGPIVSRDTGRCLEVEMSKDANFGLRLVVQRCSGQKWMIRN 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	47/123 (38%)
		pp-GalNAc-T	113..417	CDD:133004	100/315 (32%)
		Ricin_B_lectin	433..546	CDD:279046	29/141 (21%)
		RICIN	435..548	CDD:238092	30/141 (21%)
Galnt9	NP_001116116.1	pp-GalNAc-T	155..454	CDD:133004	100/316 (32%)
		Ricin_B_lectin	465..593	CDD:279046	29/141 (21%)
		RICIN	467..595	CDD:238092	30/141 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345988
Domainoid	1	1.000	43	1.000	Domainoid score	I12053
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.830