DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7304 and Galnt2

DIOPT Version :9

Sequence 1:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	XP_038953584.1	Gene:	Galnt2 / 292090	RGDID:	1310692	Length:	570	Species:	Rattus norvegicus

Alignment Length:	507	Identity:	137/507 - (27%)
Similarity:	236/507 - (46%)	Gaps:	63/507 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 YNSWLAERIPLRRSLPDLRDHRCQKLEYDEDSDEMKPASIIMIFRNEQLVVLLRTLHSLVERTPK 139
            :|...::::.:.||:||.|..:||:.::..|   :...|:::.|.||....||||:.|:::|:|.
  Rat   103 FNQVESDKLRMDRSIPDTRHDQCQRKQWRVD---LPATSVVITFHNEARSALLRTVVSVLKRSPP 164

  Fly   140 YLYIELILVNDHSDTDFWNDKLSLIFFDNYVHRYIHPKARILHLPEQVGLIKARNLAASEAKAEN 204
            :|..|:|||:|:|:.......|..|           .|.|:|....:.||:::|...|..|:|:.
  Rat   165 HLIKEIILVDDYSNDPEDGALLGKI-----------EKVRVLRNDRREGLMRSRVRGADAAQAKV 218

  Fly   205 LVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPILDNLDEQTLAY-QRSIERRGMYDWSLTRR--- 265
            |.|:|:..|....||.|||:.:||....:.:||:|.::.....| ..|.:.:|.:||:|..:
  Rat   219 LTFLDSHCECNERWLEPLLERVAEDRTRVVSPIIDVINMDNFQYVGASADLKGGFDWNLVFKWDY 283

  Fly   266 EVPLSRARRSHLPWPYEVAAVRT-----SVFAIPAVWFQDISNFDNNLRGFGAAELELSFKVWCT 325
            ..|..|..|...|    ||.::|     .:|.:..::|:::..:|..:..:|...||:||:||..
  Rat   284 MTPEQRRSRQGNP----VAPIKTPMIAGGLFVMDKLYFEELGKYDMMMDVWGGENLEISFRVWQC 344

  Fly   326 GGRIVQVPCSRVGHLQPKDEDYLKRYGDLHKMGEQKSRNLKRIIEVWTGDLKSAIYKYQPHLLNI 390
            ||.:..:|||||||:..|...|....|.    |...:||.:|..|||..:.|...|...|...|:
  Rat   345 GGSLEIIPCSRVGHVFRKQHPYTFPGGS----GTVFARNTRRAAEVWMDEFKHFYYAAVPSARNV 405

  Fly   391 SEGDLNEPRKLYKQNECQSFKEFINDITPGLNHVAALNRTDYASGHVKTLEFPKKCL-TINAKSQ 454
            ..|::....:|.|:..|:.||.:::::.|.|.   ..:..|.|.|   .|:....|| |:...:.
  Rat   406 PYGNIQSRLELRKKLGCKPFKWYLDNVYPELR---VPDHQDIAFG---ALQQGTNCLDTLGHFAD 464

  Fly   455 NLF-LERCSTNNTLQNWTLTYVKDLRVAGNICAEV---RPNLRLGYSFCHSLGGRQSWHYDSVSN 515
            .:. :..|......|.|.||..|.::.. ::|..|   .|...:....|.....||.|      .
  Rat   465 GVVGIYECHNAGGNQEWALTKEKSVKHM-DLCLTVVDRSPGSLIRLQGCRENDSRQKW------E 522

  Fly   516 QLMSNTK--------CLEFTDELN--IFLAICDAANGKQRWILDNINLSVMQ 557
            |:..|:|        ||:.....:  :.:.:|..|. .|:|   ..:|::.|
  Rat   523 QIEGNSKLRHVGSNLCLDSRTAKSGGLSVEVCGPAL-SQQW---KFSLNLQQ 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	40/122 (33%)
		pp-GalNAc-T	113..417	CDD:133004	95/312 (30%)
		Ricin_B_lectin	433..546	CDD:279046	27/127 (21%)
		RICIN	435..548	CDD:238092	27/127 (21%)
Galnt2	XP_038953584.1	pp-GalNAc-T	138..433	CDD:133004	95/313 (30%)
Galnt2	XP_038953584.1	Ricin_B_lectin	445..562	CDD:395527	27/127 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810