DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7304 and Galntl6

DIOPT Version :9

Sequence 1:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	XP_017168336.2	Gene:	Galntl6 / 270049	MGIID:	1913581	Length:	695	Species:	Mus musculus

Alignment Length:	568	Identity:	173/568 - (30%)
Similarity:	274/568 - (48%)	Gaps:	75/568 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LLHRDLSSWDGLMGPLSHPGLGENGSASYLSVPSWEIDEYTQGWRYYLYNSWLAERIPLRRSLPD 91
            |..:|...::.:.......|.||:|.    ..|..|.|.....:|...:|.:::..|.|.|||||
Mouse   158 LRRKDWHDYESIQRDALRSGKGEHGK----PYPLTEEDRDDSAYRENGFNIFVSNNIALERSLPD 218

  Fly    92 LRDHRCQKLEYDEDSDEMKPASIIMIFRNEQLVVLLRTLHSLVERTPKYLYIELILVNDHSDTDF 156
            :|...|:...|.|   .:...|||:.|.||....||||:||::.|||:.|..|:|||:|.||.:.
Mouse   219 IRHANCKHKMYLE---RLPNTSIIIPFHNEGWTSLLRTIHSIINRTPESLIAEIILVDDFSDREH 280

  Fly   157 WNDKLSLIFFDNYVHRYIHPKARILHLPEQVGLIKARNLAASEAKAENLVFVDAQVEFTNGWLSP 221
            ..|||     ::|:.|:  .|.||:...::.|||:.|.|.||.|:.|.|.|:|:..|....||.|
Mouse   281 LKDKL-----EDYMARF--SKVRIVRTKKREGLIRTRLLGASVARGEVLTFLDSHCEVNVNWLPP 338

  Fly   222 LLDTIAEQSYTLATPILDNLDEQTLAY--QRSIERRGMYDWSLTRREVP----LSRARRSHLPWP 280
            ||:.||....|:..|::|.:|.....|  |.....||.:||.:..:.:|    |.||..|.   |
Mouse   339 LLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRADPSD---P 400

  Fly   281 YEVAAVRTSVFAIPAVWFQDISNFDNNLRGFGAAELELSFKVWCTGGRIVQVPCSRVGHLQPKDE 345
            :|...:...:||:...||.::..:|..|..:|..:.|:|||||..||.:..||||||||:..|..
Mouse   401 FESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRKYV 465

  Fly   346 DYLKRYGDLHKM--GEQKSRNLKRIIEVWTGDLKSAIYKYQPHLLNISEGDLNEPRKLYKQNECQ 408
            .|        |:  |...:|||||:.|.|..:....||:.:|...::|.||::..::|.|:.:|:
Mouse   466 PY--------KVPSGTSLARNLKRVAETWMDEFAEYIYQRRPEYRHLSTGDISAQKELRKRLKCK 522

  Fly   409 SFKEFINDIT-------PGLNHVAALNRTDYASGHVKTLEFPKKCLTI--NAKSQNLFLERCSTN 464
            .||.|:..:.       |.:..:.|      |.|.::::. ...|:..  .|....|.|:.|..:
Mouse   523 DFKWFMAAVAWDVPKYYPPVEPLPA------AWGEIRSVA-ANLCVDSKHGATGTELRLDVCVKD 580

  Fly   465 NTLQNW------TLTYVKDLRV-----AGNICAEVRPNLRLGYSF------CHSLGGRQSWHY-- 510
            .:.:.|      |..:.:|:|.     ....|.:.     :.:|.      ||.:.|.|.|.|
Mouse   581 GSERTWSHEQLFTFGWREDIRPGEPLHTRKFCLDA-----ISHSSPVTLYDCHGMKGNQLWGYRE 640

  Fly   511 DSVSNQLMSNTKCLEFT-DELNIFLAICDAANGKQRWILDNINLSVMQ 557
            |......:||: |::.. .|..||:|.||..:..|:||.::||::|::
Mouse   641 DRTLFHPVSNS-CMDCNPSEKKIFMARCDPLSETQQWIFEHINMTVLE 687

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	51/122 (42%)
		pp-GalNAc-T	113..417	CDD:133004	114/311 (37%)
		Ricin_B_lectin	433..546	CDD:279046	30/134 (22%)
		RICIN	435..548	CDD:238092	30/134 (22%)
Galntl6	XP_017168336.2	pp-GalNAc-T	237..532	CDD:133004	114/312 (37%)
Galntl6	XP_017168336.2	Ricin_B_lectin	548..676	CDD:366226	30/134 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842564
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.940