Protein Alignment CG7304 and GALNT3

DIOPT Version :9

• Sequence 1: NP_996098.1
• Gene: CG7304 / 39713
• FlyBaseID: FBgn0036527
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_004473.2
• Gene: GALNT3 / 2591
• HGNCID: 4125
• Length: 633
• Species: Homo sapiens
• Alignment Length: 564
• Identity: 158/564 - (28%)
• Similarity: 255/564 - (45%)
• Gaps: 119/564 - (21%)

  Fly    48 GENGSA---SYLSVPSWEIDEYTQGWRYYLYNSWLAERIPLRRSL-PDLRDHRCQKLEYDEDSDE 108
            |.:|.|   :.|||.  |..|..:|...:.:|::.::||.|.|.| ||.|...|.:.:: :....
Human   122 GASGKAFKTTNLSVE--EQKEKERGEAKHCFNAFASDRISLHRDLGPDTRPPECIEQKF-KRCPP 183

  Fly   109 MKPASIIMIFRNEQLVVLLRTLHSLVERTPKYLYIELILVNDHSDTDFWNDKLSLIFFDNYVHRY 173
            :...|:|::|.||....||||:||::..:|..|..|:|||:|.|..::.:|||     |.||.::
Human   184 LPTTSVIIVFHNEAWSTLLRTVHSVLYSSPAILLKEIILVDDASVDEYLHDKL-----DEYVKQF 243

  Fly   174 IHPKARILHLPEQVGLIKARNLAASEAKAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPIL 238
              ...:|:...|:.|||.||.|.|:.|.||.|.|:||..|...|||.|||..|||....:.:|.:
Human   244 --SIVKIVRQRERKGLITARLLGATVATAETLTFLDAHCECFYGWLEPLLARIAENYTAVVSPDI 306

  Fly   239 DNLDEQTLAYQR-----SIERRGMYDWSLTRREVPL---SRARRSHLPWPYEVAAVRTSVFAIPA 295
            .::|..|..:.:     |...||.:||||:.....|   .:.||....:|.:.......:|:|..
Human   307 ASIDLNTFEFNKPSPYGSNHNRGNFDWSLSFGWESLPDHEKQRRKDETYPIKTPTFAGGLFSISK 371

  Fly   296 VWFQDISNFDNNLRGFGAAELELSFKVWCTGGRIVQVPCSRVGHLQPKDEDYLKRYGDLHKMGEQ 360
            .:|:.|.::|..:..:|...:|:||:||..||::..:|||.|||:      :..:.......|.|
Human   372 EYFEYIGSYDEEMEIWGGENIEMSFRVWQCGGQLEIMPCSVVGHV------FRSKSPHSFPKGTQ 430

  Fly   361 K-SRNLKRIIEVWTGDLKSAIYKYQPHLLNISE----GDLNEPRKLYKQNECQSFKEFINDITPG 420
            . :||..|:.|||..:.|...|:.......|.:    |||::..::..:.:|::|..::|:|.|.
Human   431 VIARNQVRLAEVWMDEYKEIFYRRNTDAAKIVKQKAFGDLSKRFEIKHRLQCKNFTWYLNNIYPE 495

  Fly   421 LNHVAALNRTDYASGHVKTLEFPKKCLTINAKSQNLFLERCSTNNTLQNWTLTYVKDLRVAGNIC 485
            : :|..||  ...||::|::..| .||.:...:|.        ...|..:|
Human   496 V-YVPDLN--PVISGYIKSVGQP-LCLDVGENNQG--------GKPLIMYT-------------- 534

  Fly   486 AEVRPNLRLGYSFCHSLGGRQSWHYDSVSNQLMSNTK---CLEFT-------------------- 527
                         ||.|||.|.:.| |..:::..|.:   ||...
Human   535 -------------CHGLGGNQYFEY-SAQHEIRHNIQKELCLHAAQGLVQLKACTYKGHKTVVTG 585

  Fly   528 --------DEL--NIFLAICDAANGK-------------QRWIL 548
                    |:|  |.||.:|.:|||:             |:|||
Human   586 EQIWEIQKDQLLYNPFLKMCLSANGEHPSLVSCNPSDPLQKWIL 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	51/122 (42%)
		pp-GalNAc-T	113..417	CDD:133004	101/316 (32%)
		Ricin_B_lectin	433..546	CDD:279046	30/158 (19%)
		RICIN	435..548	CDD:238092	30/158 (19%)
GALNT3	NP_004473.2	Catalytic subdomain A	184..293		48/115 (42%)
		pp-GalNAc-T	188..493	CDD:133004	101/317 (32%)
		Catalytic subdomain B	356..418		20/67 (30%)
		Ricin_B_lectin	506..627	CDD:306998	30/157 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810