Protein Alignment CG7304 and GALNT1

DIOPT Version :9

• Sequence 1: NP_996098.1
• Gene: CG7304 / 39713
• FlyBaseID: FBgn0036527
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_001371367.1
• Gene: GALNT1 / 2589
• HGNCID: 4123
• Length: 559
• Species: Homo sapiens
• Alignment Length: 575
• Identity: 162/575 - (28%)
• Similarity: 286/575 - (49%)
• Gaps: 56/575 - (9%)

  Fly    12 FKY--IVLP---VWIFIVLLLL-------------HRDLSSWDGLMGPLS--HPGLGENGSASYL 56
            |.|  :||.   :|:.:.:.||             .|.|.:.| ::.|:.  |.|.||.|..  :
Human     4 FAYCKVVLATSLIWVLLDMFLLLYFSECNKCDEKKERGLPAGD-VLEPVQKPHEGPGEMGKP--V 65

  Fly    57 SVPSWEIDEYTQGWRYYLYNSWLAERIPLRRSLPDLRDHRCQKLEYDEDSDEMKPASIIMIFRNE 121
            .:|..:.::..:.::...:|...:|.|.|.|||||:|...|:...|   .|.:...|::::|.||
Human    66 VIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVY---PDNLPTTSVVIVFHNE 127

  Fly   122 QLVVLLRTLHSLVERTPKYLYIELILVNDHSDTDFWNDKLSLIFFDNYVHRYIHPKARILHLPEQ 186
            ....||||:||::.|:|:::..|::||:|.|:.||....|     ::||.:...| ..::.:.::
Human   128 AWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPL-----ESYVKKLKVP-VHVIRMEQR 186

  Fly   187 VGLIKARNLAASEAKAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPILDNLDEQTLAYQRS 251
            .|||:||...|:.:|.:.:.|:||..|.|.|||.|||..|.....|:..||:|.:.:.|..|...
Human   187 SGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAG 251

  Fly   252 IERR-GMYDWSLTRREVPLSR----ARRSHLPWPYEVAAVRTSVFAIPAVWFQDISNFDNNLRGF 311
            .:.. |.::|.|..|..|:.:    .|:.....|.....:...:|:|...:||:|..:|..:..:
Human   252 SDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIW 316

  Fly   312 GAAELELSFKVWCTGGRIVQVPCSRVGHLQPKDEDYLKRYGDLHKMGEQKSRNLKRIIEVWTGDL 376
            |...||:||::|..||.:..|.||.|||:..|...|....|    .|:..::|.:|:.|||..:.
Human   317 GGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGG----TGQIINKNNRRLAEVWMDEF 377

  Fly   377 KSAIYKYQPHLLNISEGDLNEPRKLYKQNECQSFKEFINDITPGLNHVAALNRTDYASGHVKTLE 441
            |:..|...|.:..:..||::....|..:.:|:.|..::.:|.|.    :.:.|..::.|.::.:|
Human   378 KNFFYIISPGVTKVDYGDISSRVGLRHKLQCKPFSWYLENIYPD----SQIPRHYFSLGEIRNVE 438

  Fly   442 FPKKCLTINAKSQN--LFLERCSTNNTLQNWTLTYVKDLRVAGNICAEV-RPNLRLGYSFCHSLG 503
             ..:||...|:.:|  :.:..|......|.::.|..|::| ..::|.:| :.|..:....||.|.
Human   439 -TNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIR-TDDLCLDVSKLNGPVTMLKCHHLK 501

  Fly   504 GRQSWHYDSV--SNQLMSNTKCLE-FTDELNIFLAICDAANG--KQRWILDNINL 553
            |.|.|.||.|  :.|.:::.:||: .|:|.:...:|.| .||  .|:|:|.|:.|
Human   502 GNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRD-CNGSRSQQWLLRNVTL 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	42/122 (34%)
		pp-GalNAc-T	113..417	CDD:133004	92/308 (30%)
		Ricin_B_lectin	433..546	CDD:279046	33/120 (28%)
		RICIN	435..548	CDD:238092	34/120 (28%)
GALNT1	NP_001371367.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	45..65		7/22 (32%)
		Catalytic subdomain A	115..225		41/115 (36%)
		pp-GalNAc-T	119..419	CDD:133004	92/309 (30%)
		Catalytic subdomain B	285..347		21/61 (34%)
		Ricin_B_lectin	432..548	CDD:395527	33/118 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810