Protein Alignment CG7304 and GALNT1

DIOPT Version :10

• Sequence 1: NP_996098.1
• Gene: CG7304 / 39713
• FlyBaseID: FBgn0036527
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_065207.2
• Gene: GALNT1 / 2589
• HGNCID: 4123
• Length: 559
• Species: Homo sapiens
• Alignment Length: 575
• Identity: 162/575 - (28%)
• Similarity: 286/575 - (49%)
• Gaps: 56/575 - (9%)

  Fly    12 FKY--IVLP---VWIFIVLLLL-------------HRDLSSWDGLMGPLS--HPGLGENGSASYL 56
            |.|  :||.   :|:.:.:.||             .|.|.:.| ::.|:.  |.|.||.|..  :
Human     4 FAYCKVVLATSLIWVLLDMFLLLYFSECNKCDEKKERGLPAGD-VLEPVQKPHEGPGEMGKP--V 65

  Fly    57 SVPSWEIDEYTQGWRYYLYNSWLAERIPLRRSLPDLRDHRCQKLEYDEDSDEMKPASIIMIFRNE 121
            .:|..:.::..:.::...:|...:|.|.|.|||||:|...|:...|   .|.:...|::::|.||
Human    66 VIPKEDQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVY---PDNLPTTSVVIVFHNE 127

  Fly   122 QLVVLLRTLHSLVERTPKYLYIELILVNDHSDTDFWNDKLSLIFFDNYVHRYIHPKARILHLPEQ 186
            ....||||:||::.|:|:::..|::||:|.|:.||....|     ::||.:...| ..::.:.::
Human   128 AWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPL-----ESYVKKLKVP-VHVIRMEQR 186

  Fly   187 VGLIKARNLAASEAKAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPILDNLDEQTLAYQRS 251
            .|||:||...|:.:|.:.:.|:||..|.|.|||.|||..|.....|:..||:|.:.:.|..|...
Human   187 SGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVCPIIDVISDDTFEYMAG 251

  Fly   252 IERR-GMYDWSLTRREVPLSR----ARRSHLPWPYEVAAVRTSVFAIPAVWFQDISNFDNNLRGF 311
            .:.. |.::|.|..|..|:.:    .|:.....|.....:...:|:|...:||:|..:|..:..:
Human   252 SDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIW 316

  Fly   312 GAAELELSFKVWCTGGRIVQVPCSRVGHLQPKDEDYLKRYGDLHKMGEQKSRNLKRIIEVWTGDL 376
            |...||:||::|..||.:..|.||.|||:..|...|....|    .|:..::|.:|:.|||..:.
Human   317 GGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGG----TGQIINKNNRRLAEVWMDEF 377

  Fly   377 KSAIYKYQPHLLNISEGDLNEPRKLYKQNECQSFKEFINDITPGLNHVAALNRTDYASGHVKTLE 441
            |:..|...|.:..:..||::....|..:.:|:.|..::.:|.|.    :.:.|..::.|.::.:|
Human   378 KNFFYIISPGVTKVDYGDISSRVGLRHKLQCKPFSWYLENIYPD----SQIPRHYFSLGEIRNVE 438

  Fly   442 FPKKCLTINAKSQN--LFLERCSTNNTLQNWTLTYVKDLRVAGNICAEV-RPNLRLGYSFCHSLG 503
             ..:||...|:.:|  :.:..|......|.::.|..|::| ..::|.:| :.|..:....||.|.
Human   439 -TNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIR-TDDLCLDVSKLNGPVTMLKCHHLK 501

  Fly   504 GRQSWHYDSV--SNQLMSNTKCLE-FTDELNIFLAICDAANG--KQRWILDNINL 553
            |.|.|.||.|  :.|.:::.:||: .|:|.:...:|.| .||  .|:|:|.|:.|
Human   502 GNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRD-CNGSRSQQWLLRNVTL 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	pp-GalNAc-T	113..417	CDD:133004	92/308 (30%)
		beta-trefoil_Ricin_Pgant8-like	432..549	CDD:467339	34/124 (27%)
GALNT1	NP_065207.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	45..65		7/22 (32%)
		Catalytic subdomain A	115..225		41/115 (36%)
		pp-GalNAc-T	119..419	CDD:133004	92/309 (30%)
		Catalytic subdomain B	285..347		21/61 (34%)
		beta-trefoil_Ricin_GALNT1	426..552	CDD:467344	36/128 (28%)