Protein Alignment CG7304 and Galnt11

DIOPT Version :10

• Sequence 1: NP_996098.1
• Gene: CG7304 / 39713
• FlyBaseID: FBgn0036527
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_659157.1
• Gene: Galnt11 / 231050
• MGIID: 2444392
• Length: 608
• Species: Mus musculus
• Alignment Length: 570
• Identity: 168/570 - (29%)
• Similarity: 269/570 - (47%)
• Gaps: 95/570 - (16%)

  Fly    36 DGLM-GPLSHPGLGENGSASYLSVPSWEIDEYTQ--GWRYYLYNSWLAERIPLRRSLPDLRDHRC 97
            |.|| ..:..|..|.:.|:|.|.:...|.|:..:  |::.:.:|..::.|:...|.:||.|:..|
Mouse    77 DRLMNNHIEDPDKGLSKSSSELGMIFNERDQELRDLGYQKHAFNMLISNRLGYHRDVPDTRNAEC 141

  Fly    98 QKLEYDEDSDEMKPASIIMIFRNEQLVVLLRTLHSLVERTPKYLYIELILVNDHSDTDFWNDKLS 162
            ::..|..|   :..|||::.|.||....||||:||:|:|||.:|..|:|||:|.||.|....:|
Mouse   142 RRKSYPTD---LPTASIVICFYNEAFSALLRTVHSVVDRTPAHLLHEIILVDDSSDFDDLKGEL- 202

  Fly   163 LIFFDNYVHRYIHPKARILHLPEQVGLIKARNLAASEAKAENLVFVDAQVEFTNGWLSPLLDTIA 227
                |.|:.||:..|.:::...::.|||:.|.:.|:.|..|.|||:|:..|....||.|||..|.
Mouse   203 ----DEYIQRYLPAKVKVIRNMKREGLIRGRMIGAAHATGEVLVFLDSHCEVNVMWLQPLLAIIL 263

  Fly   228 EQSYTLATPILDNLDEQTLAYQRSIERRGMYDWSLTRREVPLSRARRSHLPW------------- 279
            |..:|:..|::|.:...||||..|...||.::|.|             |..|
Mouse   264 EDPHTVVCPVIDIISADTLAYSSSPVVRGGFNWGL-------------HFKWDLVPVSELGGPDG 315

  Fly   280 ---PYEVAAVRTSVFAIPAVWFQDISNFDNNLRGFGAAELELSFKVWCTGGRIVQVPCSRVGHLQ 341
               |.....:...:||:...:|.|:..:|:.:..:|...||:||::|..||::..:|||||||:.
Mouse   316 ATAPIRSPTMAGGLFAMNRQYFNDLGQYDSGMDIWGGENLEISFRIWMCGGKLFILPCSRVGHIF 380

  Fly   342 PKDEDYLKRYGDLHKMGEQKSRNLKRIIEVWTGDLKSAIYKYQPHLLNISEGDLNEPRKLYKQNE 406
            .|...|....|.     :..:.|..|:..||..:.|...:..:|.|.|.|.|:::|..:|.|:..
Mouse   381 RKRRPYGSPEGQ-----DTMTHNSLRLAHVWLDEYKEQYFSLRPDLKNKSFGNISERVELRKKLG 440

  Fly   407 CQSFKEFINDI-----TPGLN----HVAALNRTD-----------YASGHVKTLEFPKKCLTINA 451
            |||||.::::|     .||.|    ....:||..           |   |::|    .|||....
Mouse   441 CQSFKWYLDNIYPEMQIPGPNAKPQQPVLINRGPKRPRVLQRGRLY---HLQT----NKCLVAQG 498

  Fly   452 KSQN----LFLERCSTNNTLQNWTLTYVKDLRVAGNIC---AEVR----PNLRLGYSFCHSLGGR 505
            :|..    :.|:.|...:..|.|......:|.:...:|   :|.|    |.|..    ||..||.
Mouse   499 RSSQKGGLVLLKTCDYGDPTQVWIYNEDHELILNNLLCLDMSETRSSDPPRLMK----CHGSGGS 559

  Fly   506 QSWHYDSVSNQL--MSNTKCLEFTDELN----IFLAICDAANGKQRWILD 549
            |.|.:.. :|:|  :|..:||...|.::    :.:||||.:: .|:|.|:
Mouse   560 QQWTFGK-NNRLYQVSVGQCLRVMDLMDQKGYVGMAICDGSS-SQQWRLE 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	pp-GalNAc-T	113..417	CDD:133004	105/319 (33%)
		beta-trefoil_Ricin_Pgant8-like	432..549	CDD:467339	35/133 (26%)
Galnt11	NP_659157.1	Catalytic subdomain A	150..261		48/115 (42%)
		pp-GalNAc-T	154..452	CDD:133004	105/320 (33%)
		Catalytic subdomain B	319..381		21/61 (34%)
		beta-trefoil_Ricin_GALNT11	478..604	CDD:467318	34/138 (25%)