DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7304 and gly-10

DIOPT Version :9

Sequence 1:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001041036.2	Gene:	gly-10 / 178343	WormBaseID:	WBGene00001635	Length:	703	Species:	Caenorhabditis elegans

Alignment Length:	512	Identity:	152/512 - (29%)
Similarity:	251/512 - (49%)	Gaps:	52/512 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 YNSWLAERIPLRRSLPDLRDHRCQKLEYDEDSDEMKPASIIMIFRNEQLVVLLRTLHSLVERTPK 139
            ||:::::.|.|.||:.|:|...|:.:.|   |.::...|:|..|..|....|||:::|::.|:|.
Worm   206 YNAYISDMISLNRSIKDIRHKECKNMMY---SAKLPTVSVIFPFHEEHNSTLLRSVYSVINRSPP 267

  Fly   140 YLYIELILVNDHSDTDFWNDKLSLIFFDNYVHRYIHPKARILHLPEQVGLIKARNLAASEAKAEN 204
            .|..|:|||:|.|:.......|......|.:...:    ::|...::.|||:.|.|.|.:|..|.
Worm   268 ELLKEIILVDDFSEKPALRQPLEDFLKKNKIDHIV----KVLRTKKREGLIRGRQLGAQDATGEI 328

  Fly   205 LVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPILDNLDEQTLAYQRSIE-RRGMYDWSLTRREVP 268
            |:|:||..|....||.||||.|||...|:..|.:|.:|.:|...:...| .||.:||:...:.:|
Worm   329 LIFLDAHSEANYNWLPPLLDPIAEDYRTVVCPFVDVIDCETYEVRPQDEGARGSFDWAFNYKRLP 393

  Fly   269 LSRARRSHLPWPYEVAAVRTSVFAIPAVWFQDISNFDNNLRGFGAAELELSFKVWCTGGRIVQVP 333
            |::..|.....|:....:....|||.|.||.::..:|..|..:|..:.|||||||...||:|..|
Worm   394 LTKKDRESPTKPFNSPVMAGGYFAISAKWFWELGGYDEGLDIWGGEQYELSFKVWQCHGRMVDAP 458

  Fly   334 CSRVGHLQPKDEDYLKRYGDLHK--MGEQKSRNLKRIIEVWTGDLKSAIYKYQPHLLNISEGDLN 396
            ||||.|:      |..:|.....  ||:..|||.||:.|||..|.|..:||::|.:.|...|||.
Worm   459 CSRVAHI------YRCKYAPFKNAGMGDFVSRNYKRVAEVWMDDYKETLYKHRPGVGNADAGDLK 517

  Fly   397 EPRKLYKQNECQSFKEFINDITPGLNHVAALNRTDY---------ASGHVKTL--EFPKKCLTIN 450
            ..:.:.::.:|:||..|:.:|        |.::..|         |.|.::.:  .|   |:...
Worm   518 LMKGIREKLQCKSFDWFMKEI--------AFDQDKYYPAVEPKASAEGEIRNVGTNF---CIDTQ 571

  Fly   451 AKSQN--LFLERCSTNNT----LQNWTLTYVKDLRVAG-NICAEVRPNLRLGYSF---CHSLGGR 505
            .|.||  ..|.:|::::.    .|:..||...|:|..| .||.:...::......   |||:.|.
Worm   572 FKEQNQRFGLRKCTSDDKDGGGEQDLRLTRWHDIRPKGRKICFDCSTSVDKAPVILFDCHSMKGN 636

  Fly   506 QSWHYDSVSNQLMS--NTKCLEFTDELNIFLAI--CDAANGKQRWILDNINLSVMQS 558
            |.:.|.....|:..  :.:||...:....||.:  ||:::..|:|....::..::::
Worm   637 QLFKYRVAQKQIYHPISGQCLTADENGKGFLHMKKCDSSSDLQKWAWQTVDNELLET 693

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	42/122 (34%)
		pp-GalNAc-T	113..417	CDD:133004	106/306 (35%)
		Ricin_B_lectin	433..546	CDD:279046	31/128 (24%)
		RICIN	435..548	CDD:238092	31/128 (24%)
gly-10	NP_001041036.2	pp-GalNAc-T	241..539	CDD:133004	107/315 (34%)
		Ricin_B_lectin	555..681	CDD:279046	31/128 (24%)
		RICIN	557..681	CDD:238092	30/126 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166015
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276134at2759
OrthoFinder	1	1.000	-	-		FOG0001284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950