DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7304 and gly-8

DIOPT Version :9

Sequence 1:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001366981.1	Gene:	gly-8 / 176595	WormBaseID:	WBGene00001633	Length:	421	Species:	Caenorhabditis elegans

Alignment Length:	448	Identity:	107/448 - (23%)
Similarity:	203/448 - (45%)	Gaps:	76/448 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 KYIVLPVWIFIVLLLL---------------HRDLSSWDGLMGPLS----HPGLGENGSASYLSV 58
            :::||.:::|..::..               :.:|..|..|. ||:    :..|.||.:.:....
Worm     3 RHVVLSIFVFAGIVFAAEEAEKLPKCEHVDPYENLEGWLDLK-PLTERKCNHTLKENLTEAESKK 66

  Fly    59 PSWEIDEYTQGWRYYLYNSWLAERIPLRRSLPDLRDHRCQKLEYDEDSDEMKPASIIMIFRNEQL 123
            ..|       |.:.:.:::..:|::...|::.......|::.:||....    .|:::|..||.|
Worm    67 SEW-------GIKSFAFDALSSEKLGPNRNVGKQAHKLCEEEKYDASYS----TSVVVIHHNEAL 120

  Fly   124 VVLLRTLHSLVERTPKYLYIELILVNDHSDTDFWNDKLSLIFFDNYVHRYIHPKARILHLPEQV- 187
            ..:||.::.::|.|||.|..|::|..|.|:.            |:.:.:::...|:|..|.:::
Worm   121 STILRMINGIIEFTPKSLLKEIVLYEDASEE------------DHVLTKHLEKFAKIKGLEDKLI 173

  Fly   188 --------GLIKARNLAASEAKAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPILDNLDEQ 244
                    |||:|:..|:..|..|.:||:|:..|....||.|||..|.|...::..|::|.::..
Worm   174 IKRSEYRQGLIRAKVHASRLATGEVIVFMDSHCEVAERWLEPLLQPIKEDPKSIVLPVVDLINPV 238

  Fly   245 TLAYQRSIERRGMYDWSLTRREVPLSRARRSHLPW-----------PYEVAAVRTSVFAIPAVWF 298
            :..|..|:..:..:||..|.:.:        :|||           |:...|:...:.|:...:|
Worm   239 SFDYSPSMVAKSGFDWGFTFKWI--------YLPWEYFETPENNVKPFNSPAMPGGLLAMRKEYF 295

  Fly   299 QDISNFDNNLRGFGAAELELSFKVWCTGGRIVQVPCSRVGHLQPKDEDYLKRYGDLHKMGEQKSR 363
            .::..:|..:..:|:..:|||.|.|..|||:|..|||||||:......|..:.|     .:....
Worm   296 VELGEYDMGMEIWGSENIELSLKAWLCGGRVVVAPCSRVGHVFRMRRPYTSKPG-----MDTALY 355

  Fly   364 NLKRIIEVWTGDLKSAIYKYQPHLLNISEGDLNEPRKLYKQNECQSFKEFINDITPGL 421
            |..|:.:.|.|:.:|..:..:|....:..|||.||.::..:.:|:..|.||.::.|.|
Worm   356 NAVRVAKTWLGEYESKFFAVKPRGAKMVFGDLTEPMQVKDRLKCKDMKWFIENVYPEL 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	38/131 (29%)
		pp-GalNAc-T	113..417	CDD:133004	87/323 (27%)
		Ricin_B_lectin	433..546	CDD:279046
		RICIN	435..548	CDD:238092
gly-8	NP_001366981.1	pp-GalNAc-T	110..410	CDD:133004	87/324 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG29074
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820