Protein Alignment CG7304 and Galnt10

DIOPT Version :10

• Sequence 1: NP_996098.1
• Gene: CG7304 / 39713
• FlyBaseID: FBgn0036527
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_598950.2
• Gene: Galnt10 / 171212
• MGIID: 1890480
• Length: 603
• Species: Mus musculus
• Alignment Length: 573
• Identity: 169/573 - (29%)
• Similarity: 270/573 - (47%)
• Gaps: 86/573 - (15%)

  Fly    32 LSSW---DGLMGPLSHPGLGENGSASYLSVPSWEIDEYTQGWRYYLYNSWLAERIPLRRSLPDLR 93
            |..|   :.:.......|.||.|.    ..|..:.:...|.:|...:|.:::::|.|.|||||:|
Mouse    71 LKDWHNKEAIRRDAQRVGYGEQGK----PYPMTDAERVDQAYRENGFNIYVSDKISLNRSLPDIR 131

  Fly    94 DHRCQKLEYDEDSDEMKPASIIMIFRNEQLVVLLRTLHSLVERTPKYLYIELILVNDHSDTDFWN 158
            ...|....|.|   .:...|||:.|.||....||||:||::.|:|..|..|::||:|.||.:...
Mouse   132 HPNCNSKLYLE---TLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLK 193

  Fly   159 DKLSLIFFDNYVHRYIHPKARILHLPEQVGLIKARNLAASEAKAENLVFVDAQVEFTNGWLSPLL 223
            ..|     ::|:  .:.|..|||...::.|||:.|.|.||.|..:.:.|:|:..|....||.|||
Mouse   194 KPL-----EDYM--ALFPSVRILRTKKREGLIRTRMLGASAATGDVVTFLDSHCEANVNWLPPLL 251

  Fly   224 DTIAEQSYTLATPILDNLDEQTLAY--QRSIERRGMYDWSLTRREVP----LSRARRSHLPWPYE 282
            |.||....|:..|::|.:|.....|  |.....||.:||.:..:.:|    |.:|..|.   |:|
Mouse   252 DRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSD---PFE 313

  Fly   283 VAAVRTSVFAIPAVWFQDISNFDNNLRGFGAAELELSFKVWCTGGRIVQVPCSRVGHLQPKDEDY 347
            ...:...:||:...||.::..:|..|..:|..:.|:|||||..|||:..:|||||||:..|...|
Mouse   314 SPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPY 378

  Fly   348 LKRYGDLHKM--GEQKSRNLKRIIEVWTGDLKSAIYKYQPHLLNISEGDLNEPRKLYKQNECQSF 410
                    |:  |...:|||||:.|||..:....||:.:|...::|.||:...:||.....|:||
Mouse   379 --------KVPAGVSLARNLKRVAEVWMDEYAEYIYQRRPEYRHLSAGDVVAQKKLRVSLNCKSF 435

  Fly   411 KEFINDIT-------PGLNHVAALNRTDYASGHVKT----LEFPKKCLTINAKSQNLFLERC--- 461
            |.|:..|.       |.:...||      |.|.::.    |....|..|:.:.   |.||.|
Mouse   436 KWFMTKIAWDLPKFYPPVEPPAA------AWGEIRNVGTGLCTDTKLGTLGSP---LRLETCIRG 491

  Fly   462 ---STNNTLQNWTLTYVKDLRVAGNICAEVRPNLRLGYSF-------------CHSLGGRQSWHY 510
               :..|::|.:|.|:.:|:|...       |.....:.|             |||:.|.|.|.|
Mouse   492 RGEAAWNSMQVFTFTWREDIRPGD-------PQHTKKFCFDAVSHTSPVTLYDCHSMKGNQLWKY 549

  Fly   511 --DSVSNQLMSNTKCLEFTD-ELNIFLAICDAANGKQRWILDNINLSVMQSAN 560
              |......:|.: |::.:: :..:|:..|:.::..|:|:.::.|.:|:::.|
Mouse   550 RKDKTLYHPVSGS-CMDCSESDHRVFMNTCNPSSLTQQWLFEHTNSTVLENFN 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	pp-GalNAc-T	113..417	CDD:133004	110/311 (35%)
		beta-trefoil_Ricin_Pgant8-like	432..549	CDD:467339	31/142 (22%)
Galnt10	NP_598950.2	Catalytic subdomain A	144..253		43/115 (37%)
		pp-GalNAc-T	148..443	CDD:133004	110/312 (35%)
		Catalytic subdomain B	311..373		25/61 (41%)
		Flexible loop. /evidence=ECO:0000250	373..384		3/18 (17%)
		beta-trefoil_Ricin_GALNT10	454..603	CDD:467354	36/165 (22%)