DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7304 and GALNTL5

DIOPT Version :9

Sequence 1:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	XP_016867282.1	Gene:	GALNTL5 / 168391	HGNCID:	21725	Length:	496	Species:	Homo sapiens

Alignment Length:	454	Identity:	123/454 - (27%)
Similarity:	207/454 - (45%)	Gaps:	74/454 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 VWIFIVLLLLHRD-LSSWD-GLMGPLS--HPGLGENGSASYLS--VPSWEI-------------- 63
            :|..::.:.||.: :|||. ....|||  .||...:....|.|  :|...:
Human    71 IWTALLFIYLHHNHVSSWQKKSQEPLSAWSPGKKVHQQIIYGSEQIPKPHVIVKRTDEDKAKSML 135

  Fly    64 --------DEYTQGWRYYLYNSWLAERIPLRRSLPDLRDHRCQKLEYDEDSDEMKPASIIMIFRN 120
                    .|..:....|.:|..::..:.:.|.:||.|...|.:..|..   .:..|||::.|.|
Human   136 GTDFNHTNPELHKELLKYGFNVIISRSLGIEREVPDTRSKMCLQKHYPA---RLPTASIVICFYN 197

  Fly   121 EQLVVLLRTLHSLVERTPKYLYIELILVNDHSDTDFWNDKLSLIFFDNYVHRYIHPKARILHLPE 185
            |:...|.:|:.|:...||.|...|:|||:|.|..|...:||      :|.......|.:|:...:
Human   198 EECNALFQTMSSVTNLTPHYFLEEIILVDDMSKVDDLKEKL------DYHLETFRGKVKIIRNKK 256

  Fly   186 QVGLIKARNLAASEAKAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPILDNLDEQTLAYQR 250
            :.|||:||.:.||.|..:.|||:|:..|....||.|||..||:....:..|::|.:|::||.|:.
Human   257 REGLIRARLIGASHASGDVLVFLDSHCEVNRVWLEPLLHAIAKDPKMVVCPLIDVIDDRTLEYKP 321

  Fly   251 SIERRGMYDWSLTRREVPLSRARRSHLPW----------------PYEVAAVRTSVFAIPAVWFQ 299
            |...||.:||:|             ...|                |....|:...:|||...:|.
Human   322 SPLVRGTFDWNL-------------QFKWDNVFSYEMDGPEGSTKPIRSPAMSGGIFAIRRHYFN 373

  Fly   300 DISNFDNNLRGFGAAELELSFKVWCTGGRIVQVPCSRVGHLQPKDEDYLKRYGDLHKMGEQKSRN 364
            :|..:|.::..:|...||||.::|..||::..:|||||||:..      |:.|....:....:.|
Human   374 EIGQYDKDMDFWGRENLELSLRIWMCGGQLFIIPCSRVGHISK------KQTGKPSTIISAMTHN 432

  Fly   365 LKRIIEVWTGDLKSAIYKYQPHLLNISEGDLNEPRKLYKQNECQSFKEFINDITPGLNHVAALN 428
            ..|::.||..:.|...:..:|.|..::.|::.|..:|.|:..|:||:.:::::.|.|.  |::|
Human   433 YLRLVHVWLDEYKEQFFLRKPGLKYVTYGNIRERVELRKRLGCKSFQWYLDNVFPELE--ASVN 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	44/122 (36%)
		pp-GalNAc-T	113..417	CDD:133004	95/319 (30%)
		Ricin_B_lectin	433..546	CDD:279046
		RICIN	435..548	CDD:238092
GALNTL5	XP_016867282.1	GT2	187..437	CDD:224137	84/274 (31%)
GALNTL5	XP_016867282.1	pp-GalNAc-T	190..486	CDD:133004	95/320 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152525
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740