Protein Alignment CG7304 and GALNT15

DIOPT Version :10

• Sequence 1: NP_996098.1
• Gene: CG7304 / 39713
• FlyBaseID: FBgn0036527
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_473451.3
• Gene: GALNT15 / 117248
• HGNCID: 21531
• Length: 639
• Species: Homo sapiens
• Alignment Length: 526
• Identity: 148/526 - (28%)
• Similarity: 235/526 - (44%)
• Gaps: 106/526 - (20%)

  Fly    79 LAERIPLRRSLPDLRDHRCQKLEYDEDSDEMKPASIIMIFRNEQLVVLLRTLHSLVERTPKYLYI 143
            |:.||||:|:||::|...|.: ::.:||  :..||:|:.|.:|....||||:||:::..|:....
Human   163 LSARIPLQRALPEVRHPLCLQ-QHPQDS--LPTASVILCFHDEAWSTLLRTVHSILDTVPRAFLK 224

  Fly   144 ELILVNDHSDTDFWNDKLSLIFFDNYVHRYIHPKARILHLPEQVGLIKARNLAASEAKAENLVFV 208
            |:|||:|.|........||     .||.|.  ...::|...:::|.|:||.|.|:.|..:.|||:
Human   225 EIILVDDLSQQGQLKSALS-----EYVARL--EGVKLLRSNKRLGAIRARMLGATRATGDVLVFM 282

  Fly   209 DAQVEFTNGWLSPLLDTIAEQSYTLATPILDNLDEQTLAYQRSIE-RRGMYDWSLTRREVPLSRA 272
            ||..|...|||.|||..||.....:.:|::|.:|.:|..|..|.: :||:.||.|.....||...
Human   283 DAHCECHPGWLEPLLSRIAGDRSRVVSPVIDVIDWKTFQYYPSKDLQRGVLDWKLDFHWEPLPEH 347

  Fly   273 RRSHLPWPYEVAAVRT-----SVFAIPAVWFQDISNFDNNLRGFGAAELELSFKVWCTGGRIVQV 332
            .|..|..|  ::.:|:     .|.|:...:||:...:|:.:...|...||||||.|..||.:..:
Human   348 VRKALQSP--ISPIRSPVVPGEVVAMDRHYFQNTGAYDSLMSLRGGENLELSFKAWLCGGSVEIL 410

  Fly   333 PCSRVGHLQPKDEDYLKRYGDLHKMGEQKS--RNLKRIIEVWTGDLKSAIYKYQPHLLNISEG-- 393
            |||||||:....        |.|...:|::  ||..||.|.|.|..|...||:.|...::|:.
Human   411 PCSRVGHIYQNQ--------DSHSPLDQEATLRNRVRIAETWLGSFKETFYKHSPEAFSLSKAEK 467

  Fly   394 -DLNEPRKLYKQNECQSFKEFINDITPGLNHVAALNRTDYASGHVKTLEFPKKCLTINAKSQNLF 457
             |..|..:|.::..|::|..|:.::.|.|                    :|.:
Human   468 PDCMERLQLQRRLGCRTFHWFLANVYPEL--------------------YPSE------------ 500

  Fly   458 LERCSTNNTLQNWTLTYVKDLRVAGNI---------CAEVRPNLRLGYS------------FCHS 501
             .|.|.:..|.|..|....|.:..|:|         |::.|....|.::            .|.:
Human   501 -PRPSFSGKLHNTGLGLCADCQAEGDILGCPMVLAPCSDSRQQQYLQHTSRKEIHFGSPQHLCFA 564

  Fly   502 LGGRQ--------------SWHYDSVSNQLMSNT---KCLEFTDELN---IFLAICDAANGKQRW 546
            :...|              ..|:|...|.::.:.   ||:|...:.|   ::|..|| ...:|:|
Human   565 VRQEQVILQNCTEEGLAIHQQHWDFQENGMIVHILSGKCMEAVVQENNKDLYLRPCD-GKARQQW 628

  Fly   547 ILDNIN 552
            ..|.||
Human   629 RFDQIN 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	pp-GalNAc-T	113..417	CDD:133004	104/314 (33%)
		beta-trefoil_Ricin_Pgant8-like	432..549	CDD:467339	26/157 (17%)
GALNT15	NP_473451.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	106..155
		Catalytic subdomain A	190..299		43/115 (37%)
		pp-GalNAc-T	194..493	CDD:133004	104/315 (33%)
		Catalytic subdomain B	358..420		23/61 (38%)
		beta-trefoil_Ricin_GALNT15	502..629	CDD:467320	24/127 (19%)