DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7304 and galnt9

DIOPT Version :9

Sequence 1:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	XP_002931923.1	Gene:	galnt9 / 100490061	XenbaseID:	XB-GENE-948907	Length:	604	Species:	Xenopus tropicalis

Alignment Length:	545	Identity:	152/545 - (27%)
Similarity:	250/545 - (45%)	Gaps:	66/545 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 MGPLSHP-GLGENGSASYLSVPSWEID-EYTQGWRYYLYNSWLAERIPLRRSLPDLRDHRCQKLE 101
            ||.:..| |||:.|.|:.|...|.|.: :|.:    |.||:.|::||.|.||:||.|..:|:::.
Frog    86 MGLVEGPGGLGQGGMAATLRDDSHESETKYEE----YGYNAQLSDRISLDRSIPDYRPKKCKQMT 146

  Fly   102 YDEDSDEMKPASIIMIFRNEQLVVLLRTLHSLVERTPKYLYIELILVNDHSDTDFWNDKLSLIF- 165
            |.:|..::   :::.||.||.|.|:||::||:|..||.||..|:|||:|:|      |.:.|.|
Frog   147 YPDDLPQI---AVVFIFVNEALSVILRSVHSVVNHTPSYLLKEIILVDDNS------DNVELKFN 202

  Fly   166 FDNYVHRYIHPKARILHLPEQVGLIKARNLAASEAKAENLVFVDAQVEFTNGWLSPLLDTIAEQS 230
            .|.||::......:|:....:.|||:||......|.|..:.|.||.|||..||..|::..|.|..
Frog   203 LDQYVNKRYPGLVKIVRNTRREGLIRARIQGWKAASAPIVGFFDAHVEFNTGWAEPVITRIKEDR 267

  Fly   231 YTLATPILDNLDEQTLAYQRSIERRGMYDWSLTRREV--PLSRARRSHLPWPYEVAAVRTSVFAI 293
            ..:..|.:||:...:...|:.......|:|.|....:  |.....:.....|....|:....|.:
Frog   268 RRIILPAIDNIKYNSFEVQQYANAAHGYNWGLWCMYITPPQDWLEKGDESAPIRTPAMIGCSFVV 332

  Fly   294 PAVWFQDISNFDNNLRGFGAAELELSFKVWCTGGRIVQVPCSRVGHLQ------PKDEDYLKRYG 352
            ...:|.||...|..:..:|...:||..:||..||.:..:|||||.|::      ..|.||..:
Frog   333 DRAYFGDIGLLDPGMEVYGGENIELGMRVWQCGGSMEVLPCSRVAHIERTKKPYNNDIDYYAK-- 395

  Fly   353 DLHKMGEQKSRNLKRIIEVWTGDLKSAIY-KYQPHLLN--ISEGDLNEPRKLYKQNECQSFKEFI 414
                      ||..|..|||..:.||.:| .:...:.|  :..||::|...|.::.:|:|||.::
Frog   396 ----------RNALRAAEVWMDEFKSHVYMAWNIPMTNPGVDFGDVSERVALRQKLQCRSFKWYL 450

  Fly   415 NDITPGLNHVAALNRTDYASGHVKTLEFPKKCLTINAKSQN---LF--------LERCSTNNTLQ 468
            .::.|   .:...|.| ...|.::..:....||...::..|   |:        |.|.|:...||
Frog   451 ENVYP---EMRVYNNT-ITYGELRNSKATGYCLDQGSEDDNKAILYPCHGMSSQLVRYSSEGLLQ 511

  Fly   469 NWTL---TYVKDLRVAGNICAEVRPNLRLGYSFCHSL--GGRQSWHYDSVSNQLMSNT-KCL--E 525
            ...|   :::.|.:...:......|.|:.    |..:  ..::.|.:...|..:..:| :||  |
Frog   512 LGPLGSTSFLPDTKCLIDDGKGRTPTLKK----CDDVPRSPQKLWDFTQSSPIVNRDTGRCLEVE 572

  Fly   526 FTDELNIFLAICDAANGKQRWILDN 550
            .:.:.|..|.:.......|:||:.|
Frog   573 MSKDANFGLRLVVQRCSGQKWIIRN 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	46/123 (37%)
		pp-GalNAc-T	113..417	CDD:133004	95/315 (30%)
		Ricin_B_lectin	433..546	CDD:279046	24/131 (18%)
		RICIN	435..548	CDD:238092	25/131 (19%)
galnt9	XP_002931923.1	pp-GalNAc-T	156..454	CDD:133004	95/315 (30%)
galnt9	XP_002931923.1	Ricin_B_lectin	465..593	CDD:366226	24/131 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910