DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7304 and Galnt6

DIOPT Version :9

Sequence 1:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	NP_001165534.1	Gene:	Galnt6 / 100361647	RGDID:	2319726	Length:	622	Species:	Rattus norvegicus

Alignment Length:	542	Identity:	157/542 - (28%)
Similarity:	251/542 - (46%)	Gaps:	77/542 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 GENGSASYLSVPSW---EIDEYTQGWRYYLYNSWLAERIPLRRSL-PDLRDHRCQKLEYDEDSDE 108
            |.:|.|  .....|   |..|..:|::.:.:|::.::||.|:||| ||.|...|    .|:....
  Rat   114 GADGKA--FQKKEWTLLETQEKDEGYKKHCFNAFASDRISLQRSLGPDTRPPEC----VDQKFRR 172

  Fly   109 MKP---ASIIMIFRNEQLVVLLRTLHSLVERTPKYLYIELILVNDHSDTDFWNDKLSLIFFDNYV 170
            ..|   .|::::|.||....||||::|::..:|..|..|:|||:|.|..:...:||
  Rat   173 CPPLPTTSVVIVFHNEAWSTLLRTVYSVLHTSPAILLKEIILVDDASTDEHLKEKL--------- 228

  Fly   171 HRYIHPK--ARILHLPEQVGLIKARNLAASEAKAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTL 233
            .||:...  .|::...|:.|||.||.|.||.|:||.|.|:||..|..:|||.|||..|||....:
  Rat   229 ERYVQQLQIVRVVRQQERKGLITARLLGASVAQAEVLTFLDAHCECFHGWLEPLLARIAEDKTAV 293

  Fly   234 ATPILDNLDEQTLAYQRSIER-----RGMYDWSLTRREVPL---SRARRSHLPWPYEVAAVRTSV 290
            .:|.:..:|..|..:.:.:.|     ||.:|||||.....|   .:.||....:|.:.......:
  Rat   294 VSPDIVTIDLNTFQFSKPMRRGKAHSRGNFDWSLTFGWEMLPEHEKQRRKDETYPIKSPTFAGGL 358

  Fly   291 FAIPAVWFQDISNFDNNLRGFGAAELELSFKVWCTGGRIVQVPCSRVGHL--------QPKDEDY 347
            |:|...:|:.|..:||.:..:|...:|:||:||..||::..:|||.|||:        .||....
  Rat   359 FSISKAYFEHIGTYDNQMEIWGGENVEMSFRVWQCGGQLEIIPCSVVGHVFRTKSPHTFPKGTSV 423

  Fly   348 LKRYGDLHKMGEQKSRNLKRIIEVWTGDLKSAIYKYQPHLLNISE----GDLNEPRKLYKQNECQ 408
            :             :||..|:.|||..|.|...|:.......:::    ||::|..:|.:|..|.
  Rat   424 I-------------ARNQVRLAEVWMDDYKKIFYRRNLQAAKMAKENNFGDVSERLRLREQLHCH 475

  Fly   409 SFKEFINDITPGLNHVAALNRTDYASGHVKTLEFPKKCLTI---NAKSQNLFLERCSTNNTLQNW 470
            :|..:::::.|.: .|..||.|  .||.:|.|. ..:||.:   |...:.|.:..|......|.:
  Rat   476 NFSWYLHNVYPEM-FVPDLNPT--FSGAIKNLG-TSQCLDVGENNRGGKPLIMYVCHNLGGNQYF 536

  Fly   471 TLTYVKDLR--VAGNICAEVRPNLRLGYSFCHSLGGR------QSWH--YDSVSNQLMSNTKCLE 525
            ..|..:|||  :...:|.....: .||...|..:|..      :.|.  .|.:...|.|.| ||.
  Rat   537 EYTSQRDLRHNIGKQLCLHASGS-TLGLRNCQFIGKNSEVPKDEEWELTQDQLIRNLGSGT-CLT 599

  Fly   526 FTDELNIFLAICDAANGKQRWI 547
            ..|: ...:|.|:.::..|.|:
  Rat   600 SKDK-KPAMAPCNPSDPYQLWL 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	49/127 (39%)
		pp-GalNAc-T	113..417	CDD:133004	101/325 (31%)
		Ricin_B_lectin	433..546	CDD:279046	30/125 (24%)
		RICIN	435..548	CDD:238092	30/126 (24%)
Galnt6	NP_001165534.1	pp-GalNAc-T	180..485	CDD:133004	101/326 (31%)
Galnt6	NP_001165534.1	Ricin_B_lectin	497..619	CDD:395527	30/125 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346004
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840