DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7304 and galnt13

DIOPT Version :9

Sequence 1:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster
Sequence 2:	XP_005168002.1	Gene:	galnt13 / 100330695	ZFINID:	ZDB-GENE-091204-444	Length:	581	Species:	Danio rerio

Alignment Length:	551	Identity:	150/551 - (27%)
Similarity:	259/551 - (47%)	Gaps:	78/551 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 VWIFI-VLLLLH----------RDLSSWDGLMGPLS--HPGLGENGSASYLSVPSWEIDEYTQGW 70
            ||:.: |.|||:          :|.|....|...:|  |...||.|.|  :.:|..|.|:..:.:
Zfish    16 VWVLVDVFLLLYFSECNKCDNRKDHSLLPALRAVMSRAHEAPGEMGKA--VVIPKEEQDKMKELF 78

  Fly    71 RYYLYNSWLAERIPLRRSLPDLRDHRCQKLEYDEDSDEMKPASIIMIFRNEQLVVLLRTLHSLVE 135
            :...:|...::.|.|.|||||:|...|:...|   .|::...||:::|.||....||||:||.:.
Zfish    79 KINQFNLMASDMIALNRSLPDVRLDGCKTKTY---PDDLPNTSIVIVFHNEAWSTLLRTVHSAIN 140

  Fly   136 RTPKYLYIELILVNDHSDTDFWNDKLSLIFFDNYVHRYIHPKARILHLPEQVGLIKARNLAASEA 200
            |:|:.|..|::||:|.|:.||..:||     ::||.....| .|||.:.::.|||:||...|:..
Zfish   141 RSPRQLLYEILLVDDASERDFLKEKL-----EDYVATLEVP-VRILRMEQRTGLIRARLRGAAAT 199

  Fly   201 KAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTLATPILDNLDEQTLAYQRSIERR-GMYDWSLTR 264
            :.:.:.|:||..|.|.|||.||:..|.|....:..||:|.:.::|..|....:.. |.::|.|..
Zfish   200 RGQVITFLDAHCECTTGWLEPLMARIKEDRRAVVCPIIDVISDETFEYMAGSDMTYGGFNWKLNF 264

  Fly   265 REVPLSR----ARRSHLPWPYEVAAVRTSVFAIPAVWFQDISNFDNNLRGFGAAELELSFKVWCT 325
            |..|:.:    .|:.....|.....:...:|:|...:|::|..:|:.:..:|...||:||::|..
Zfish   265 RWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRTYFEEIGTYDSGMDIWGGENLEMSFRIWQC 329

  Fly   326 GGRIVQVPCSRVGHLQPKDEDYLKRYGDLHKMGEQKSRNLKRIIEVWTGDLKSAIYKYQPHLLNI 390
            ||.:..|.||.|||:..|...|....|    .|:..::|.:|:.|||..:.|...|...|.::.:
Zfish   330 GGSLEIVTCSHVGHVFRKATPYSFPGG----TGQVINKNNRRLAEVWMDEFKDFFYIISPGVVRV 390

  Fly   391 SEGDLNEPRKLYKQNECQSFKEFINDITPGLNHVAALNRTDYASGHVKTLEFPKKCLTINAKSQN 455
            ..||::..:.|.:..:|:.|..::.::.|.    :.:.|..|:.|.::.:|
Zfish   391 DYGDVSSRKALRESLKCKPFSWYLENVYPD----SQIPRRYYSLGEIRNVE-------------- 437

  Fly   456 LFLERCSTNNTLQNWTLTYVKDLRVAGNICAEVRPNLRLGYSFCHSLGGRQSWHYDSVSNQLMSN 520
                   ||..:.|           .|.     :.|.::|:..||.:||.|.:.| :...::.::
Zfish   438 -------TNQCVDN-----------MGR-----KENEKVGFFNCHGMGGNQVFSY-TADKEIRTD 478

  Fly   521 TKCLEFTDELN--IFLAICDAANGKQRWILD 549
            ..||: ...||  :.:..|....|.|.:..|
Zfish   479 DLCLD-ASRLNGPVVMLKCHHMKGNQMFEYD 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	47/122 (39%)
		pp-GalNAc-T	113..417	CDD:133004	95/308 (31%)
		Ricin_B_lectin	433..546	CDD:279046	21/114 (18%)
		RICIN	435..548	CDD:238092	21/114 (18%)
galnt13	XP_005168002.1	Glyco_tranf_2_3	115..359	CDD:290369	81/253 (32%)
		pp-GalNAc-T	118..418	CDD:133004	95/309 (31%)
		RICIN	431..560	CDD:238092	22/117 (19%)
		Ricin_B_lectin	431..558	CDD:279046	22/117 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587014
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840