Protein Alignment ARHGDIB and RhoGDI

DIOPT Version :10

• Sequence 1: NP_001166.3
• Gene: ARHGDIB / 397
• HGNCID: 679
• Length: 201
• Species: Homo sapiens
• Sequence 2: NP_649162.1
• Gene: RhoGDI / 40179
• FlyBaseID: FBgn0036921
• Length: 201
• Species: Drosophila melanogaster
• Alignment Length: 286
• Identity: 58/286 - (20%)
• Similarity: 106/286 - (37%)
• Gaps: 92/286 - (32%)

Human     6 SEAEAEALAAARERSRLFLSGLELVQQGAEARVFRGRFQGRAAVVKHRFPKSYRHPELEARLGRR 70
            |::.||.:..|.::||..:.           |.|.....|...::|    :.:...|:|
  Fly    12 SDSIAEKMPDALKQSRYHMK-----------RCFASFVGGGKKLMK----REHLMNEIE------ 55

Human    71 RTVQEARA-----------LLRC-RRAGIAAPVVFFVDYAS--NCLYMEEIE--------DSVTV 113
            :.::::|.           :|.| :.|.:..|   ||..|:  |..:.|.::        |.:|.
  Fly    56 KCIEDSRERSKILEGLFGYILTCTQEAAVVPP---FVALAARPNPGFWEYVKVNSGDLTVDEITA 117

Human   114 RDYI---QSTMET--EKDPQCL-------------LDLARRMGQ-----------VLAGMHD--Q 147
            .||:   :|..:.  .||...|             |.|:..:|:           .|.|..|  :
  Fly   118 TDYLKLKESVFDESWSKDENALEIDFGAIDFTSPRLSLSSSIGKGADYISKFISSKLGGKSDKLE 182

Human   148 DLIHGDLTTSNMLLRRPLAQLHIVLIDFGLSFVSGLPEDKGVDLYVLEKAFLSTHPHTETAFE-- 210
            .|:       |.|||......::::.| .|:.|:.|  .|.:.|.|:..:..|.|...||..:
  Fly   183 PLL-------NYLLRLNHHGENLMIND-DLNTVAKL--QKSLMLAVIVVSTYSKHTPYETFAQRL 237

Human   211 ---AFLKSYGASSKKSSPVLKKLDEV 233
               .|.|.:|.::::....:..|.||
  Fly   238 KEMGFEKGWGDTAERVKETMIILSEV 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARHGDIB	NP_001166.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		6/31 (19%)
		Rho_GDI	23..198	CDD:460449	42/227 (19%)
RhoGDI	NP_649162.1	Rho_GDI	11..199	CDD:460449	41/217 (19%)