Protein Alignment Phs and ZNF124

DIOPT Version :10

• Sequence 1: NP_648789.3
• Gene: Phs / 39697
• FlyBaseID: FBgn0036522
• Length: 971
• Species: Drosophila melanogaster
• Sequence 2: NP_001284497.1
• Gene: ZNF124 / 7678
• HGNCID: 12907
• Length: 351
• Species: Homo sapiens
• Alignment Length: 342
• Identity: 104/342 - (30%)
• Similarity: 156/342 - (45%)
• Gaps: 38/342 - (11%)

  Fly   482 NSNQKQ---LDKSEANAGKSKMVDQVHQQMPVESAKDHQQMTEEPTNSTKRKR------GRKERK 537
            |..|::   ||.|:.|..:..|.:.......:.:..:.|.:.::..||::..|      |..
Human    21 NFTQEEWALLDPSQKNLYRDVMQETFRNLASIGNKGEDQSIEDQYKNSSRNLRHIISHSGNN--- 82

  Fly   538 SPTPVLIPLGDKEIKEEP----ELPERRMRKSRQHVDYVVEIKDEEEDDDEVEEAEVDDDSSATI 598
                   |.|.:|..::|    :..:..:..:|.|.|.|:...:........|:. .:..||..|
Human    83 -------PYGCEECGKKPCTCKQCQKTSLSVTRVHRDTVMHTGNGHYGCTICEKV-FNIPSSFQI 139

  Fly   599 SPHNSSTDESFTSIK-----RESSEESQHNGIGGIHT------CNFCGKTFKRFSRMQDHLRLHT 652
            ...|.:.::.:..::     ..|...::|.   .|||      |..|||.|.|.|.::||.|.||
Human   140 HQRNHTGEKPYECMECGKALGFSRSLNRHK---RIHTGEKRYECKQCGKAFSRSSHLRDHERTHT 201

  Fly   653 GEKPYVCGQCGRAFRLKMRLVEHQLRHRAEKAYKCDICSMPLATKQDLSLHMRHHKNDRRYKCDK 717
            |||||.|..||:|||....|..|:..|..||.|.|..|....:....|..|::.|..:..|.|.:
Human   202 GEKPYECKHCGKAFRYSNCLHYHERTHTGEKPYVCMECGKAFSCLSSLQGHIKAHAGEEPYPCKQ 266

  Fly   718 CNKGFVRSSDLSIHVRIHTGEKPYSCDLCGKAFRARQNLVVHRRTHLGDKPIQCELCDKRFARKI 782
            |.|.|..:|.|..|.:.|..:|||.|:.|||.||...:|..|.|||.|:||.:|:.|.|.|:|..
Human   267 CGKAFRYASSLQKHEKTHIAQKPYVCNNCGKGFRCSSSLRDHERTHTGEKPYECQKCGKAFSRAS 331

  Fly   783 DMRVHMRRHTGEKPYNC 799
            .:..|.:.|||||||.|
Human   332 TLWKHKKTHTGEKPYKC 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phs	NP_648789.3	COG5048	<594..787	CDD:227381	74/203 (36%)
		C2H2 Zn finger	631..651	CDD:275368	10/19 (53%)
		C2H2 Zn finger	715..735	CDD:275368	7/19 (37%)
		C2H2 Zn finger	743..763	CDD:275368	9/19 (47%)
		C2H2 Zn finger	771..791	CDD:275368	6/19 (32%)
		zf-H2C2_2	783..808	CDD:463886	9/17 (53%)
		C2H2 Zn finger	799..816	CDD:275370	1/1 (100%)
ZNF124	NP_001284497.1	KRAB	12..53	CDD:460171	7/31 (23%)
		C2H2 Zn finger	96..116	CDD:275368	4/19 (21%)
		C2H2 Zn finger	124..144	CDD:275368	4/20 (20%)
		C2H2 Zn finger	152..172	CDD:275368	2/22 (9%)
		COG5048	<176..338	CDD:227381	66/161 (41%)
		C2H2 Zn finger	180..200	CDD:275368	10/19 (53%)
		C2H2 Zn finger	208..228	CDD:275368	8/19 (42%)
		C2H2 Zn finger	236..256	CDD:275368	4/19 (21%)
		C2H2 Zn finger	264..284	CDD:275368	7/19 (37%)
		C2H2 Zn finger	292..312	CDD:275368	9/19 (47%)
		C2H2 Zn finger	320..340	CDD:275368	6/19 (32%)