Protein Alignment Phs and ZNF35

DIOPT Version :10

• Sequence 1: NP_648789.3
• Gene: Phs / 39697
• FlyBaseID: FBgn0036522
• Length: 971
• Species: Drosophila melanogaster
• Sequence 2: NP_003411.3
• Gene: ZNF35 / 7584
• HGNCID: 13099
• Length: 527
• Species: Homo sapiens
• Alignment Length: 151
• Identity: 35/151 - (23%)
• Similarity: 55/151 - (36%)
• Gaps: 42/151 - (27%)

  Fly    62 VTAASNAVRQMQNFPFYDKPMRIQYAKSKSDYVTKAEGSFVPKEKKMKQEEKVERKRHAEETQQP 126
            |.:|:.:.|.:       .|..:|...||.|..||:.||:.|                ...::.|
Human   492 VCSAATSHRSL-------SPQLLQQTPSKPDGATKSLGSYTP----------------GPRSRSP 533

  Fly   127 SMPN-GATTQNGMPVPPFQPSGQDTMPPNNILFIHNLPIETNSMMLQLLFEQYPGFKEIRMIEAK 190
            |:.. |.|.::|....|....|....|..|          .:|:.   .|| |||.:. ::..|.
Human   534 SLNRLGGTAEDGKRTQPHWHVGSPFTPGAN----------KDSLS---TFE-YPGPRR-KLYSAV 583

  Fly   191 PGIAFV---EYEDDVQSSMAM 208
            ||..||   .|:..|...:.:
Human   584 PGRLFVAVKPYQPQVDGEIPL 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phs	NP_648789.3	COG5048	<594..787	CDD:227381
		C2H2 Zn finger	631..651	CDD:275368
		C2H2 Zn finger	715..735	CDD:275368
		C2H2 Zn finger	743..763	CDD:275368
		C2H2 Zn finger	771..791	CDD:275368
		zf-H2C2_2	783..808	CDD:463886
		C2H2 Zn finger	799..816	CDD:275370
ZNF35	NP_003411.3	Globular domain	9..221
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..38
		COG5048	<214..369	CDD:227381
		C2H2 Zn finger	224..244	CDD:275368
		C2H2 Zn finger	252..272	CDD:275368
		C2H2 Zn finger	280..300	CDD:275368
		C2H2 Zn finger	308..328	CDD:275368
		C2H2 Zn finger	336..356	CDD:275368
		C2H2 Zn finger	364..384	CDD:275368
		COG5048	372..>449	CDD:227381
		C2H2 Zn finger	392..412	CDD:275368
		C2H2 Zn finger	420..440	CDD:275368
		C2H2 Zn finger	448..468	CDD:275368
		zf-H2C2_2	460..485	CDD:463886
		zf-C2H2	474..496	CDD:395048	1/3 (33%)
		C2H2 Zn finger	476..496	CDD:275368	1/3 (33%)
		zf-H2C2_2	488..513	CDD:463886	5/27 (19%)
		C2H2 Zn finger	504..524	CDD:275368	8/19 (42%)