Protein Alignment Phs and ZNF19

DIOPT Version :10

• Sequence 1: NP_648789.3
• Gene: Phs / 39697
• FlyBaseID: FBgn0036522
• Length: 971
• Species: Drosophila melanogaster
• Sequence 2: NP_008892.2
• Gene: ZNF19 / 7567
• HGNCID: 12981
• Length: 458
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 117/359 - (32%)
• Similarity: 164/359 - (45%)
• Gaps: 30/359 - (8%)

  Fly   539 PTPVLIPL---GDK----EIKEEPELPERRMRKSRQHVDYVVEIKD------EEEDDDEVEEAEV 590
            |.|.||.|   ||.    |.:::|  |..|.:...:.|:..::.:.      .||.|..:...::
Human    58 PKPALISLLERGDMAWGLEAQDDP--PAERTKNVCKDVETNIDSESTLIQGISEERDGMMSHGQL 120

  Fly   591 DDDSSATISP--HNSSTDESFTSIKRESSEESQHNGIGGIHTCNFCGKTFKRFSRMQDHLRLHTG 653
            ......|..|  .|....:...::|....:..:.........|..|||:|..||....|.|:|||
Human   121 KSVPQRTDFPETRNVEKHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSYYARHQRIHTG 185

  Fly   654 EKPYVCGQCGRAFRLKMRLVEHQLRHRAEKAYKCDICSMPLATKQDLSLHMRHHKNDRRYKCDKC 718
            |||:.|.:||:||.....|:.||..|..|:.|:|:.|........:|..|.|.|..||.|.|.:|
Human   186 EKPFECSECGKAFNGNSSLIRHQRIHTGERPYQCEECGRAFNDNANLIRHQRIHSGDRPYYCTEC 250

  Fly   719 NKGFVRSSDLSIHVRIHTGEKPYSCDLCGKAFRARQNLVVHRRTHLGDKPIQCELCDKRFARKID 783
            ...|..||:..||.|||||||||.|:.|||||.....|:.|::.|.|:||.:|..|.|.|.|...
Human   251 GNSFTSSSEFVIHQRIHTGEKPYECNECGKAFVGNSPLLRHQKIHTGEKPYECNECGKSFGRTSH 315

  Fly   784 MRVHMRRHTGEKPYNCDACQRGYSSRVNLLRHQEREHGIEEQVP----GSGQAD------KKHTK 838
            :..|.|.|||||||:|..|.:.::....|.||| |.|  .|:.|    ..|:|.      |:|.:
Human   316 LSQHQRIHTGEKPYSCKVCGQAFNFHTKLTRHQ-RIH--SEEKPFDCVDCGKAFSAQEQLKRHLR 377

  Fly   839 TATENEQENEPKAKAAPRRPRREKLQQKIAAQEK 872
            ..|:.......:...|....|.....|:|...||
Human   378 IHTQESSYVCDECGKALTSKRNLHQHQRIHTGEK 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phs	NP_648789.3	COG5048	<594..787	CDD:227381	72/194 (37%)
		C2H2 Zn finger	631..651	CDD:275368	9/19 (47%)
		C2H2 Zn finger	715..735	CDD:275368	8/19 (42%)
		C2H2 Zn finger	743..763	CDD:275368	8/19 (42%)
		C2H2 Zn finger	771..791	CDD:275368	7/19 (37%)
		zf-H2C2_2	783..808	CDD:463886	11/24 (46%)
		C2H2 Zn finger	799..816	CDD:275370	4/16 (25%)
ZNF19	NP_008892.2	KRAB	14..73	CDD:214630	7/14 (50%)
		COG5048	<96..426	CDD:227381	105/319 (33%)
		C2H2 Zn finger	163..183	CDD:275368	9/19 (47%)
		C2H2 Zn finger	191..211	CDD:275368	8/19 (42%)
		C2H2 Zn finger	219..239	CDD:275368	5/19 (26%)
		C2H2 Zn finger	247..267	CDD:275368	8/19 (42%)
		C2H2 Zn finger	275..295	CDD:275368	8/19 (42%)
		C2H2 Zn finger	303..323	CDD:275368	7/19 (37%)
		C2H2 Zn finger	331..351	CDD:275368	7/20 (35%)
		C2H2 Zn finger	359..379	CDD:275368	4/19 (21%)
		C2H2 Zn finger	387..407	CDD:275368	3/19 (16%)