Protein Alignment Phs and 2810021J22Rik

DIOPT Version :10

• Sequence 1: NP_648789.3
• Gene: Phs / 39697
• FlyBaseID: FBgn0036522
• Length: 971
• Species: Drosophila melanogaster
• Sequence 2: NP_765991.1
• Gene: 2810021J22Rik / 69944
• MGIID: 1917194
• Length: 539
• Species: Mus musculus
• Alignment Length: 540
• Identity: 142/540 - (26%)
• Similarity: 212/540 - (39%)
• Gaps: 129/540 - (23%)

  Fly   368 DEQDNAEKTDKKKKLNKEEGQQPVLEPLQAKKTSNQAENGATQSNNVVKVQQNAKGSKKDGTQSA 432
            ||..:.:  |.::||.::    .:||...:..:.||.:   .:...::|::|.|...|:|.....
Mouse    20 DEWQDLD--DSQRKLYRD----VMLETYSSLLSLNQCD---AKPELILKLEQGAGPWKEDNAPDQ 75

  Fly   433 QKSETNP-KHLENAETNSKDNTESVALKETIHDKQLTIDEAGKAGTQKDDNSNQKQLDKSEANAG 496
            ......| |.|:.|    :.:|....|...:.....:.:|.|:.|.....|||. .|..:.....
Mouse    76 SLPALQPMKSLKEA----RRDTGKKHLSHLLVTGSASAEERGRLGEILSMNSNH-VLHLALKTRS 135

  Fly   497 KSKMVDQVHQQM--------PVESAKDHQQMTEE-----PTNSTKR-----------KRGRKE-- 535
            .|:|..:|....        |:|     .|.|||     |:....|           :||.:.
Mouse   136 TSRMRSEVLDTWGDVYLPGGPIE-----MQATEELDHLNPSKMLPRPPAPLSLDFSAERGPQHGQ 195

  Fly   536 ----------RKSPTPVLIPLGDK----------------EIKEE-------------------- 554
                      |...|..:.||||.                .|:||
Mouse   196 CAQHGEAFDVRTVWTRTVFPLGDSSTNAFDKLALTAQEGTHIREETFDCNMCKKPFSDTCNHTRH 260

  Fly   555 --PEL-----------PERRMRKSRQHVDY--------------VVEIKDEEEDDDEVEEAEVD- 591
              |.|           |..|.:...||..:              |.::.....:.......|.:
Mouse   261 LKPHLKKQCGKCPDGEPAFRAKAGLQHTLHSWGKPRGCNDNKKCVHQMPKPRSNQSVFSSKESNC 325

  Fly   592 -----DDSSATIS--PH-NSSTDESFTSIKRESSEESQHNGIGGIHTCNFCGKTFKRFSRMQDHL 648
                 .||:.::.  || .....||.|.:|..|....:|. .|..:.|..|||.||....:..|.
Mouse   326 VKTFCPDSTLSVQQRPHTGKKPQESSTPVKINSQPRRRHR-CGRTYQCKVCGKAFKHTQNLYLHH 389

  Fly   649 RLHTGEKPYVCGQCGRAFRLKMRLVEHQLRHRAEKAYKCDICSMPLATKQDLSLHMRHHKNDRRY 713
            |.|||||||.|.:|.:.|.:|..|..||..|..||.|:|:||......:.||::|.|.|..::.|
Mouse   390 RTHTGEKPYECKECKKLFSVKSNLSVHQKTHTGEKPYECNICGNAFKRRCDLTIHQRVHTGEKPY 454

  Fly   714 KCDKCNKGFVRSSDLSIHVRIHTGEKPYSCDLCGKAFRARQNLVVHRRTHLGDKPIQCELCDKRF 778
            :|.:|.|.|...|.|.:|.|||||||||.|.:|||.|..:.||..|.:.|.|:||.:|:.|.|.|
Mouse   455 ECKECRKTFSIKSGLIVHQRIHTGEKPYECSVCGKRFNQKSNLSTHEKIHTGEKPFECKECSKAF 519

  Fly   779 ARKIDMRVHMRRHTGEKPYN 798
            :.|..:.:|.:.|.||||::
Mouse   520 SVKSYLTIHQKTHVGEKPHS 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phs	NP_648789.3	COG5048	<594..787	CDD:227381	78/195 (40%)
		C2H2 Zn finger	631..651	CDD:275368	8/19 (42%)
		C2H2 Zn finger	715..735	CDD:275368	8/19 (42%)
		C2H2 Zn finger	743..763	CDD:275368	8/19 (42%)
		C2H2 Zn finger	771..791	CDD:275368	6/19 (32%)
		zf-H2C2_2	783..808	CDD:463886	6/16 (38%)
		C2H2 Zn finger	799..816	CDD:275370	142/540 (26%)
2810021J22Rik	NP_765991.1	KRAB	8..67	CDD:214630	12/55 (22%)
		C2H2 Zn finger	323..342	CDD:275368	2/18 (11%)
		zf-C2H2	370..392	CDD:395048	8/21 (38%)
		C2H2 Zn finger	372..392	CDD:275368	8/19 (42%)
		COG5048	<396..539	CDD:227381	62/142 (44%)
		C2H2 Zn finger	400..420	CDD:275368	7/19 (37%)
		C2H2 Zn finger	428..448	CDD:275368	7/19 (37%)
		C2H2 Zn finger	456..476	CDD:275368	8/19 (42%)
		C2H2 Zn finger	484..504	CDD:275368	8/19 (42%)
		C2H2 Zn finger	512..532	CDD:275368	6/19 (32%)