Protein Alignment Phs and ZNF487

DIOPT Version :10

• Sequence 1: NP_648789.3
• Gene: Phs / 39697
• FlyBaseID: FBgn0036522
• Length: 971
• Species: Drosophila melanogaster
• Sequence 2: XP_024303897.1
• Gene: ZNF487 / 642819
• HGNCID: 23488
• Length: 244
• Species: Homo sapiens
• Alignment Length: 232
• Identity: 46/232 - (19%)
• Similarity: 72/232 - (31%)
• Gaps: 89/232 - (38%)

  Fly   554 EPELPERRMRKSRQHVDYVVEIKDEEEDDDEVEEAEVDDDSSATISPHNSSTDESFTSIKRESSE 618
            |.|.|      |:.|:|..:       |||.:|:.:.:.|.      |....|  |.:.|..:.:
Human    71 EEESP------SQSHLDCCI-------DDDLMEKRQENQDQ------HLQKVD--FVNNKTLTMD 114

  Fly   619 ESQHNGIGGIHTCNFCGKTFKRFSRMQDHLRLHTGEKPYVCGQCGRAFRLKMRLVEHQLRHRAEK 683
               .||:        .||||.          |.|..                 ::..::|.
Human   115 ---RNGV--------LGKTFS----------LDTNP-----------------ILSRKIRG---- 137

  Fly   684 AYKCDICSMPLATKQDLSLHMRHH------------------KNDRRY------KCDKCNKGFVR 724
              .||...|.|....:|.:..|..                  |.:..|      :.|...|...:
Human   138 --NCDSSGMNLNNISELIISNRSSFVRNPAECNVRGKFLLCMKRENPYARGKPLEYDGNGKAVSQ 200

  Fly   725 SSDLSIHVRIHTGEKPYSCDLCGKAFRARQNLVVHRR 761
            :.||..|..|.|.::.:..:.|||||........|:|
Human   201 NEDLFRHQYIQTLKQCFEYNQCGKAFHEEAACSTHKR 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phs	NP_648789.3	COG5048	<594..787	CDD:227381	35/192 (18%)
		C2H2 Zn finger	631..651	CDD:275368	4/19 (21%)
		C2H2 Zn finger	715..735	CDD:275368	5/19 (26%)
		C2H2 Zn finger	743..763	CDD:275368	7/19 (37%)
		C2H2 Zn finger	771..791	CDD:275368
		zf-H2C2_2	783..808	CDD:463886
		C2H2 Zn finger	799..816	CDD:275370
ZNF487	XP_024303897.1	KRAB	9..69	CDD:214630
		C2H2 Zn finger	195..211	CDD:275370	4/15 (27%)
		C2H2 Zn finger	219..238	CDD:275370	7/19 (37%)